A5114686236- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Organoboron and organosilicon chemistry
- Sulfur-Based Synthesis Techniques
- Bioactive Compounds and Antitumor Agents
- Chemical synthesis and alkaloids
- Radical Photochemical Reactions
- Media, Religion, Digital Communication
- Color perception and design
- Vanadium and Halogenation Chemistry
- Catalytic Alkyne Reactions
- Remote Sensing and Land Use
- Phenothiazines and Benzothiazines Synthesis and Activities
- Media Studies and Communication
- Oxidative Organic Chemistry Reactions
- Cultural Heritage Management and Preservation
- Cyclization and Aryne Chemistry
- Communication Studies and Media
Chongqing University
2016-2022
Chongqing University of Arts and Sciences
2012
Renmin University of China
2010
The first example of the thiyl radical promoted ligand-free iron-catalyzed oxidative cleavage alkenes using molecular oxygen (1 atm) has been developed.
The iron-catalyzed construction of Csp2-Si bonds via unreactive C-O possesses a challenging topic in organic chemistry. Herein we report an silylation aryl and alkenyl carbamates bond activation. This protocol features high efficiency broad substrate scope, enabling the late-stage biorelevant compounds thus providing good method to access valuable motifs medicinal Moreover, this enables orthogonal transformations phenol derivatives also allows for synthesis multisubstituted arenes through...
Open AccessCCS ChemistryRESEARCH ARTICLES6 Oct 2022Iron-Catalyzed Cross-Electrophile Coupling of Inert C–O Bonds with Alkyl Bromides Shuo Chen†, Zijian Wang†, Shasha Geng, Hongdan Zhu, Zhengli Liu, Yun He, Qian Peng and Zhang Feng Chen† Chongqing Key Laboratory Natural Product Synthesis Drug Research, School Pharmaceutical Sciences, University, 401331 , Wang† State Elemento-Organic Chemistry, Tianjin Biosensing Molecular Recognition, College Nankai 300071 Geng Zhu Liu He *Corresponding...
A convenient synthesis of 3,4-dihydro-2H-naphtho[2,3-b][1,4]oxazine-5,10-diones and 2,3,4,5-tetrahydro-1H-naphtho[2,3-b]azepine-6,11-diones via the copper-catalyzed intramolecular C–O/C–C coupling reaction is described. This method showed a good tolerance for functional groups was applied to natural product core structures. Some products exhibited moderate activities against lung cancer A549 cells.
The transition-metal-free multicomponent coupling of arynes, anilines, and ethylglyoxylate, proceeding via an inverse electron-demand aza Diels–Alder cycloaddition N-arylation, has been demonstrated. This protocol allows rapid access to N-aryl dihydrophenanthridine derivatives in moderate high yields at room temperature from readily available starting materials. In addition, unprecedented fluoride induced annulation ethyl(arylimino)acetates led the formation highly functionalized...
Herein we describe an iron-catalyzed borylation of alkenyl and aryl carbamates through the activation a C–O bond. This protocol exhibits high efficiency, broad substrate scope, late-stage biorelevant compounds, thus providing potential applications in medicinal chemistry. Moreover, this method enables orthogonal transformations phenol derivatives also offers good opportunities for synthesis multisubstituted arenes. Preliminary mechanistic studies suggest that FeII/FeIII catalytic cycle via...
We present a protocol for the eco-friendly synthesis of aryl and alkyl boronic esters from carboxylic acids. describe steps carboxylates preparation. further detail procedures borylated products using through iron-catalyzed decarbonylation at 100°C–130°C, followed by purification crude flash column chromatography. For complete details on use execution this protocol, please refer to Wen et al. (2022).1