Objectives. To estimate the economic burden of untreated perinatal mood and anxiety disorders (PMADs) among 2017 births in United States. Methods. We developed a mathematical model based on cost-of-illness approach to impacts exposure PMADs mothers children. Our estimated costs incurred by their babies born 2017, projected from conception through first 5 years birth cohort’s lives. determined inputs secondary data sources literature review. Results. cost $14 billion for cohort postpartum....

The role of maternal stress during pregnancy remains a focus academic and clinical inquiry, yet there are few instruments available that measure pregnancy-specific contributors to psychological state. This report examines the psychometric properties an abbreviated version Pregnancy Experience Scale (PES) designed evaluate appraisal positive negative stressors pregnancy. PES-Brief consists top 10 items endorsed as hassles uplifts from original scale. was administered 112 women with low risk,...

Abstract Background Intraoperative hypotension (IOH) is well-described in the academic setting but not community practice. IOH associated with risk of postoperative morbidity and mortality. This first report using measure definition from Centers for Medicare Medicaid Services Merit-based Incentive Payment System program. Objectives: To describe incidence setting; assess variation by patient-, procedure-, facility-level characteristics; risk-adjusted across clinicians. Methods Design...

To pilot test the effectiveness, feasibility, and acceptability of instituting a 15-pill quantity default in electronic health record for new Schedule II opioid prescriptions.A mixed-methods study two systems, including pre-post analysis prescribed focus groups or interviews with prescribers system administrators.We implemented opioids assessed before after implementation using data on 6,390 prescriptions from 448 prescribers. We then analyzed themes four staff members six prescribers.The...

Background: Along with efficacy, a microbicide's acceptability will be integral to its impact on the pandemic. Understanding Product Characteristics that users find most acceptable and determining who use which type of product are key optimizing effectiveness. Objectives: To evaluate psychometrically Important Microbicide (IMC) instrument examine relationship willingness microbicides. Results: Exploratory confirmatory factor analyses revealed 2 IMC subscales (Cronbach's coefficient α:...

Intraoperative hypotension is common and associated with organ injury death, although randomized data showing a causal relationship remain sparse. A risk-adjusted measure of intraoperative may therefore contribute to quality improvement efforts.The we developed defines as mean arterial pressure <65 mm Hg sustained for at least 15 cumulative minutes. Comparisons are based on whether clinicians have more or fewer cases than expected over 12 months, given their patient mix. The was evaluated...

To investigate women's willingness to use vaginal microbicides reduce/prevent HIV infection, using measures grounded in the individual, behavioral, and social contexts of sex.A cross-sectional study that enrolled a sample (N = 531) 18-55 year old Latina, African-American, White women U.S. between October, 2004, July, 2005.Willingness individual- context-related variables (e.g., demographics, relationship status).Exploratory confirmatory factor analyses supported one-dimensional, 8-item...

Abstract The ocean, with its rich untapped chemical biodiversity, continues to serve as a source of potentially new therapeutic agents. evaluation the diversity cultivable microorganisms from marine sponge Halichondria panicea and ocean sediment samples were examined their potential sources antimicrobial antiproliferative agents investigated. sediments collected at different depths (0.9–6 meters) locations in Florida, including Florida Keys, Port St. Joe Pensacola, Pensacola Bay, Beach, Fort...

Following intracardiac delivery of MDA-MB-231-luc-D3H2LN cells to Nu/Nu mice, systemic metastases developed in the injected animals. Bioluminescence imaging using IVIS Spectrum was employed monitor distribution and development tumor following procedure including DLIT reconstruction measure signal its location. Development metastatic lesions bone tissues triggers osteolytic activity tibia femur were evaluated longitudinally micro CT. Imaging performed a Quantum FX CT system with fast low...

In ‘ Why Abortion is Immoral ’, Don Marquis argues that abortion wrong for the same reason murder wrong, namely, it deprives a human being of an FLO, ‘future like ours,’ which future full value and experience life. Marquis’ argument rests on assumption somehow deprived by suffering early death. I argue faces ‘Epicurean Challenge’. The concept ‘deprivation’ requires some discernible individual exists who can be deprived. But if death involves total annihilation, then no to so Epicurean...

The ultimate goal of government health systems is to provide highly effective equitable services that save lives and reduce morbidity mortality. pressure conform duplicative global donor initiatives compounds existing challenges strengthening such as shortages human resources for health, weak supply chains, inadequate laboratory parallel data management systems. This article illustrates how primary care, the point entry into care system majority individuals in sub-Saharan Africa, should be...

As primary care models increasingly include nonphysician team members, more attention should be paid to patient- and family-centered (PFCC) among medical assistants (MAs). The aims of this article are describe parent perceptions PFCC by MAs assess associations between MA other their experience. To PFCC, we administered the CARE (Consultation Relational Empathy) measure parent/guardian 360 children following a visit. Perceptions were significantly associated with 6 7 measures patient...

To measure the incidence of intraoperative hypotension (IOH) during surgery in ambulatory centers (ASCs) and describe associated characteristics patients procedures.Retrospective analysis.20 ASCs.16,750 having non-emergent, non-cardiac surgery; ASA physical status 2 through 4.None.We assessed IOH using definition from Centers for Medicare & Medicaid Services (CMS) Merit-based Incentive Payment System (MIPS)-mean arterial pressure (MAP) < 65 mmHg at least 15 cumulative minutes-and three...

Objectives To evaluate the psychometric properties of Microbicide Use Self-Efficacy (MUSE) instrument and to examine correlates self-efficacy use vaginal microbicides among a sample racially ethnically diverse women living in north-eastern United States. Methods: Exploratory confirmatory factor analytic methods were used explore determine dimensionality MUSE instrument. Construct validity was assessed by examining relationships key sexual behaviour, partner communication, relationship...

An estimated half a million women give birth each year in the United States; at least 13% suffer from perinatal depression. Health care professionals are essential partners reducing burden of this illness on women, their offspring and families. We provide framework for public healthclinical collaboration that promotes population-based model addressing This approach builds upon strengths current clinical supplements individualized, treatment-focused approach. The five components our vision...