A5047642094- Congenital gastrointestinal and neural anomalies
- Intestinal Malrotation and Obstruction Disorders
- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Appendicitis Diagnosis and Management
- Gastrointestinal disorders and treatments
- Whipple's Disease and Interleukins
- Congenital Diaphragmatic Hernia Studies
- Hernia repair and management
- Esophageal and GI Pathology
- Congenital Anomalies and Fetal Surgery
- Pelvic floor disorders treatments
- Intraperitoneal and Appendiceal Malignancies
- Testicular diseases and treatments
- Diverticular Disease and Complications
- Vascular Malformations Diagnosis and Treatment
- Renal and related cancers
- Eosinophilic Esophagitis
- Infant Nutrition and Health
- Sexual Differentiation and Disorders
- Renal cell carcinoma treatment
- Vascular Malformations and Hemangiomas
- Urologic and reproductive health conditions
Children's Health Ireland at Crumlin
2014-2023
University Hospital Galway
2006-2023
Leeds Teaching Hospitals NHS Trust
2022
Temple Street Children's University Hospital
2015-2020
University of Birmingham
2020
National Children’s Research Centre
2014-2019
Nationwide Children's Hospital
2019
Our Lady's Hospital
2016
Boston Children's Hospital
2015
University College London
2013
AIM:To investigate whether the expression of plateletderived growth factor receptor-α-positive (PDGFRα + )cells is altered in Hirschsprung's disease (HD).METHODS: HD tissue specimens (n = 10) were collected at time pull-through surgery, while colonic control samples obtained colostomy closure patients with imperforate anus 10).Immunolabelling PDGFRα -cells was visualized using confocal microscopy to assess distribution these cells, Western blot analysis undertaken quantify protein...
To determine if expression of colonic tryptophan hydroxylase-2 (TPH2), a surrogate marker neuronal 5-hydroxytryptamine, is altered in Hirschsprung's-associated enterocolitis.Entire resected specimens were collected at the time pull-through operation children with Hirschsprung's disease (HSCR, n = 12). Five these patients had history pre-operative enterocolitis (HAEC). Controls colostomy closure anorectal malformation (n 10). The distribution TPH2 was evaluated using immunofluorescence and...