A5089547993- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Asymmetric Hydrogenation and Catalysis
- Crystallography and molecular interactions
- Supramolecular Self-Assembly in Materials
- Metal-Organic Frameworks: Synthesis and Applications
- Various Chemistry Research Topics
- Asymmetric Synthesis and Catalysis
- Organoboron and organosilicon chemistry
- Synthetic Organic Chemistry Methods
- Nanomaterials for catalytic reactions
- Supramolecular Chemistry and Complexes
- Organic and Molecular Conductors Research
Boston College
2019-2020
Fudan University
2014
Abstract Self-assembly has emerged as a powerful approach to generating complex supramolecular architectures. Despite there being many crystalline frameworks reported in the solid state, construction of highly soluble periodic networks three-dimensional space is still challenge. Here we demonstrate that encapsulation motif, which involves dimerization two aromatic units within cucurbit[8]uril, can be used direct co-assembly tetratopic molecular block and cucurbit[8]uril into organic...
Amines emerge, as copper bides its time Concurrent operation of two or more catalytic cycles requires a delicate balance relative rates. Zhang et al. developed an amine synthesis in which allenes and nitriles are coupled under reductive conditions. A catalyst was charged with successively borylating the allene, coupling intermediate to nitrile, then enantioselectively reducing that next amine. However, formation reaction copper-boryl complex were too slow competing hydride. By adding...
A widely applicable, practical, and scalable strategy for efficient enantioselective synthesis of β,γ-unsaturated ketones that contain an α-stereogenic center is disclosed. Accordingly, aryl, heteroaryl, alkynyl, alkenyl, allyl, or alkyl carbon with alkyl, a benzyloxy, siloxy moiety can be generated from readily available starting materials by the use commercially chiral ligands in 52–96% yield 93:7 to >99:1 enantiomeric ratio. To develop new method, conditions were identified so high...