A5027835816- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Global Cancer Incidence and Screening
- Lymphatic System and Diseases
- Breast Implant and Reconstruction
- Metastasis and carcinoma case studies
- Clinical practice guidelines implementation
- Gastrointestinal motility and disorders
- Stoma care and complications
- Infectious Diseases and Mycology
- Salivary Gland Tumors Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Gene expression and cancer classification
- Cervical Cancer and HPV Research
- Infrared Thermography in Medicine
- Blood Pressure and Hypertension Studies
- Effects of Vibration on Health
- Bone health and osteoporosis research
- Nitric Oxide and Endothelin Effects
- Intestinal Malrotation and Obstruction Disorders
- Ultrasound and Hyperthermia Applications
- Dialysis and Renal Disease Management
- Effects of Radiation Exposure
- Noise Effects and Management
Sir Charles Gairdner Hospital
2018-2021
Northamptonshire Healthcare NHS Foundation Trust
2014
City Hospital
1996
Nottingham City Hospital
1990-1996
Queen's Medical Centre
1996
Fine needle aspiration cytology (FNAC) of the breast is widely used in diagnosis carcinoma. In some centres this sometimes only diagnostic procedure performed prior to definitive treatment. A grading system based on would be helpful selection patients for appropriate therapy. The aim study, therefore, was devise such a carcinoma cytological features alone. assessed were degree cell clustering, nuclear pleomorphism, diameter, presence multiple, easily visible nucleoli and necrosis....
Introduction: Women with breast cancer are often prescribed aromatase inhibitors, which can cause rapid loss of bone mass leading to significant potential for morbidity. Vibration training has been shown be helpful in reducing turnover postmenopausal women without cancer. Aim: To examine the effect vibration stimulus on markers patients receiving inhibitors. Methods: Thirty-one survivors undergoing treatment inhibitors were randomized (n = 14) or usual care control 17). Low-frequency and...
Background Staging of axillary lymph nodes in breast cancer is important for prognostication and planning adjuvant therapy. The traditional practice proceeding to node dissection (ALND) if sentinel biopsy (SLNB) positive being challenged clinical trials are underway. For many centres, this will mean a move away from intra‐operative SLNB assessment utilization second procedure perform ALND. It sometimes perceived that delayed ALND results increased tissue damage thus morbidity. We compared...
In 1988, 985 patients presenting with breast disease, most a palpable abnormality, were investigated by the triple approach (clinical examination, imaging and fine needle aspiration cytology [FNAC]). Using FNAC, 28% of diagnosed as having carcinoma, 45% benign 4% had suspicious 3% equivocal cytology. remaining 20% inadequate aspirates. Two false positive diagnoses carcinoma made (a rate 0.7%); one was case high grade non‐Hodgkin's lymphoma other papillary lesion epithelial atypia. negative...
This article describes the introduction of abdominal massage techniques by a community team as part total bowel management programme for people with learning disabilities. A trust-wide audit prescribed laxative use this client group raised concerns, and led to more systematic approach managing constipation in An education carers proved be successful. Some reported that adopting provided further opportunity develop therapeutic relationship.
Conventional peritoneal dialysis solutions (PDS) are vasoactive. This study was conducted to identify vasoactive components of PDS and describe quantitatively such vasoactivity. Anesthetized nonheparinized rats were monitored continuously for hemodynamics while the microvasculature jejunum studied with in vivo intravital microscopy. In separate experiments, vascular reactivity rat endothelium-intact -denuded aortic rings (2 mm) ex a standard tissue bath. both studies, suffusion vessels...
Recent surgical de-escalation of the axilla in breast cancer management has led to reduced number immediate and delayed axillary lymph node dissections (ALND) after sentinel biopsies (SLNBs). We aim assess postoperative impact SLNB versus ALND on arm lymphoedema morbidity.A retrospective analysis from a prospectively collected institutional database was performed reviewing rates morbidity terms shoulder restriction patient-reported functional deficit women undergoing surgery for between 2013...
A survey amongst members of the British Society for Clinical Cytology (BSCC) was performed in 1990 and 1991 into their experience fine needle aspiration (FNA) cytology breast. Here we present findings that part covering organizational aspects service methods specimen handling. replies demonstrate differences approach to many topics covered. There is a preference examination direct smears (rather than cytospins) with air dried Giemsa staining wet fixation Papanicolaou finding nearly equal...
A survey into the practice of fine needle aspiration cytology breast amongst members British Society for Clinical Cytology in 1990 and 1991 was performed. This paper presents their reported use diagnostic categories reporting criteria found useful diagnosis benign malignant disease. wide variety are use. The used largely follow recommendations standard textbooks, but some less well recognized features were also suggested.
Abstract Purpose: This research investigated the feasibility of using B-mode ultrasound with shear-wave elastography (SWE) to evaluate structural and mechanical properties multiple tissue layers in pectoral region women chronic radiation fibrosis following breast cancer treatment. Method: Nine between one five years post unilateral conventional fractionated radiotherapy were evaluated. Both SWE used examine thickness stiffness skin, subcutaneous adipose tissue, fascia muscle both their...
Introduction:The use and timing of sentinel node biopsy in patients undergoing Neoadjuvant chemotherapy (NACT) has been debated extensively.This study aimed to evaluate the practice our tertiary centre as well effects Sentinel (SLNB) after neoadjuvant with positive disease.We aim accuracy reliability SLNB NACT disease.Methods: A retrospective analysis who had for breast cancer from 2013-2018 (5 year period).Results: reduced need axillary lymph dissection being a feasible alternative...