A5010426632- Gastrointestinal motility and disorders
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Liver Disease and Transplantation
- Intestinal and Peritoneal Adhesions
- Endometriosis Research and Treatment
- Cardiovascular Syncope and Autonomic Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Central Venous Catheters and Hemodialysis
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Fish Biology and Ecology Studies
- Pancreatitis Pathology and Treatment
- Venous Thromboembolism Diagnosis and Management
- Colorectal Cancer Screening and Detection
- Vascular Procedures and Complications
- Gastroesophageal reflux and treatments
- Pharmacological Effects and Toxicity Studies
- Pulmonary Hypertension Research and Treatments
- Female Genital Mutilation/Cutting Issues
- Humic Substances and Bio-Organic Studies
- Menstrual Health and Disorders
- Syphilis Diagnosis and Treatment
- Music Therapy and Health
University Hospital Coventry
2023-2024
Walsall Healthcare NHS Trust
2017-2023
Kalinga University
2022
University of Delhi
2022
Aultman Hospital
2017-2021
University Hospitals of Cleveland
2021
Indian Institute of Science Education and Research Mohali
2020-2021
University Hospitals Coventry and Warwickshire NHS Trust
2021
Indraprastha Apollo Hospitals
2020
Apollo Hospitals
2019
BACKGROUND & AIMS: Patients with irritable bowel syndrome constipation (IBS-C) and patients functional (FC) have similar symptoms, these disorders overlap in their diagnostic features. Little is known about physiology or the involvement of serotonin signaling. We investigated relationships between platelet-depleted plasma concentrations serotonin, gastrointestinal motor-sensory function FC IBS-C compared healthy volunteers (controls). METHODS: We measured fasting fed individuals (n =...
<h3>Objective</h3> In women presenting to gynaecological clinics with lower abdominal pain, the cause is frequently attributed endometriosis irrespective of whether it found be minimal or extensive at laparoscopy. Irritable bowel syndrome (IBS) also common in this setting, and was speculated that visceral hypersensitivity associated condition might amplifying symptoms endometriosis. <h3>Methods</h3> Visceral sensitivity balloon distension, psychological status were assessed following...
Colorectal cancer (CRC) poses a significant global health threat, necessitating early detection. Traditional diagnostic tools like optical colonoscopy have limitations prompting our '5G-SUCCEEDS' initiative to explore novel approach involving remote colon capsule endoscopy (CCE).
Bleeding from parastomal varices causes significant morbidity and mortality. Treatment options are limited, particularly in high-risk patients with underlying liver disease other comorbidities. The use of EUS-guided embolisation coils combined thrombin injection gastric has been shown to be safe effective. Our institution applied the same technique treatment varices.A retrospective review was performed 37 procedures on 24 assess efficacy safety thrombin, or without for bleeding varices. All...
Background and aim: Endoscopic ultrasound-guided drainage is a minimally invasive first-line modality for the of pancreatic fluid collection (PFC) resulting in shorter hospital stay less morbidity compared with surgical cystogastrostomy. Our aim to evaluate potential differences outcomes endoscopic ultrasound (EUS) guided transmural (EUS-TD) pseudocyst (PP) walled-off necrosis (WON).Method: We retrospectively reviewed 100 consecutive EUS-guided drainages PFC utilising EUS reports; clinical...
Bone and soft tissue infections are difficult problems in orthopedic surgery. Infections resulting chronic osteomyelitis if established to eradicate. The delivery of local antibiotics for the treatment open infected wounds musculo skeletal system is a more logical approach treat these infections. Antibiotics given systemically unable achieve minimum inhibitory concentration areas which ischemic or relatively avascular. And also over prolonged period lead significant toxicity side effects...
Moringa oleifera Lam. extract appeared to boost the pregnancy while some literature reported abortive activity causing a dilemma for users. Present study was conducted rule out fertility enhancement effect of extract. Ethanol evaluated at dose levels 100, 250, 500 mg/kg on fertility, implantation, decidualization and local cytokine signaling during in female Wistar rats with artificially induced decidualization. 250 led defective implantation smaller dull color implants compared control...
A 32-year-old British Asian man presented with what appeared clinically and on ultrasound to be a testicular tumour. However, syphilis serology, histology detection of Treponema pallidum DNA by polymerase chain reaction confirmed that the lesion was gumma. Without routine correct diagnosis may have been missed.
The mid-femoral head (F50 ) is a common fluoroscopic target for femoral artery (CFA) puncture during cardiac catheterization. Punctures above the inguinal ligament (marking proximal end of CFA) increase risk retroperitoneal hemorrhage and are classified as high punctures.We retrospectively analyzed 114 CT angiograms anatomic relationship to (FH) inferior epigastric (IEA). We 500 angiograms, relation mid-point CFA F50 F75 (the junction upper 3/4th lower 1/4th FH).The third (F33 (-1.4 mm) IEA...
Diabetic mellitus, a metabolic disorder, has high incidence and morbidity. Of all complications, diabetic foot ulcer is one of the commonest with 25% likelihood to develop for ulcers. Infection in dreaded complication often complicates clinical course patient managed by local systemic antibiotics. Local antibiotics are generally deemed ineffective various studies due lack an appropriate drug delivery system. The Vit D level inversely related development vascular disease. A novel strategy...
The study was aimed at developing an accessible laboratory animal model to elucidate protective and pathological roles of immune mediators during Peste des petits ruminants virus (PPRV) infection. It is because the critical type I IFNs in anti-viral defense, we assessed susceptibility IFN receptor knock out (IFNR KO) mice PPRV IFNR KO were exceedingly susceptible infection but WT animals efficiently controlled PPRV. Accordingly, infected gradually reduced their body weights succumbed within...
<h3>Introduction</h3> Gastric varices are present in 5%–33% of patients with portal hypertension incidence bleeding around 25% 2 years.<sup>1</sup> If gastric identified as the source bleeding, therapeutic options include endoscopic Methods, TIPSS, surgery and non-selective beta blockade.<sup>2</sup> There reports EUS guided coiling combined cyanoacrylate glue<sup>3</sup> but limited literature on safety efficacy coil embolisation human thrombin injection. We report our experience....
Up to a third of patients undergoing coronary angiography for angina-like chest pain are found have normal arteries and substantial proportion these individuals continue consult even attend emergency departments. Initially, usually seen by cardiologists but with accumulating evidence that the might gastrointestinal origin, it may be more appropriate them cared gastroenterologist once cardiological cause has been excluded. This review covers assessment management this challenging condition,...
<h3>Introduction</h3> A range of techniques have been described to achieve successful cannulation at ERCP, and when training in ERCP it is often difficult select the optimum approach<sup>.1</sup> There are potential advantages a wire-led approach we evaluated this our unit setting. <h3>Aim</h3> To evaluate success rates for trainers trainees using technique as default approach. <h3>Methods</h3> prospective evaluation was done with 2 experienced (previous experience 50–100 ERCPs each). The...
The regulation of PPAR? and at m-RNAs expression level is responsible for Islet ?-cell dysfunction insulin secretion seen in diabetic rats. Many traditional treatments have been recommended the alternative system medicine treatment diabetes mellitus. Stevia rebaudiana Gurmmar a nontoxic natural therapeutic agent revealed to own diuretic, hypotensive hypoglycemic properties. ground this study was examine anti-hyperglycemic property, m-RNA receptors islet ?-cells combined aqueous extracts on...
<h3>Introduction</h3> Recent studies suggest that patients identified by Rome III criteria for functional constipation (FC) and irritable bowel syndrome with (IBS-C) are not distinct groups. We have shown IBS-C exhibit limited 5-HT response to meal ingestion, plasma concentrations remaining similar fasting. Our aim was determine whether FC show a as IBS-C, investigate relationships motor-sensory function. <h3>Methods</h3> 23 (aged 19–50 years; III), 11 (25–46 III) healthy volunteers (HV)...
Percutaneous endoscopic gastrostomy (PEG) is a common procedure for an unsafe swallow or inability to maintain oral nutrition. When PEG tube needs replacement, balloon usually placed through the same, well formed and mature tract without endoscopy. We present patient with rare complication related tube, raise awareness minimise risk of this in future. A 67-year-old female presented emergency department severe abdominal pain vomiting. Her feeding displaced inwards, up feeding-balloon ports...