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Research Areas
- Nicotinic Acetylcholine Receptors Study
- Alzheimer's disease research and treatments
- Cholinesterase and Neurodegenerative Diseases
Aptuit (Italy)
2022
Abstract Introduction The neuronal mechanism driving Alzheimer's disease (AD) is incompletely understood. Methods Immunohistochemistry, pharmacology, biochemistry, and behavioral testing are employed in two pathological contexts—AD a transgenic mouse model—to investigate T14, 14mer peptide, as key signaling molecule the neuropathology. Results T14 increases AD brains progresses conspicuous 5XFAD mice, where its immunoreactivity corresponds to that seen AD: neurons immunoreactive for...
10.1002/trc2.12274
article
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cc-by-nc
Alzheimer s & Dementia Translational Research & Clinical Interventions
2022-01-01
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