A5083872885- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Sleep and Wakefulness Research
- Thermal Regulation in Medicine
- COVID-19 and Mental Health
- Infrared Thermography in Medicine
- Sleep and related disorders
- Categorization, perception, and language
- Engineering Diagnostics and Reliability
- Family and Patient Care in Intensive Care Units
- Vestibular and auditory disorders
- Respiratory Support and Mechanisms
- Spatial Cognition and Navigation
- Laser Design and Applications
- Memory and Neural Mechanisms
- Multisensory perception and integration
- Temporomandibular Joint Disorders
- Thermoregulation and physiological responses
- Acupuncture Treatment Research Studies
- Adolescent and Pediatric Healthcare
The University of Melbourne
2012-2025
Austin Health
2017
Institute for Breathing and Sleep
2017
University of Chicago
1943-1945
Background Countries worldwide are experiencing a third wave of the coronavirus disease 2019 (COVID-19) pandemic. Government-imposed restrictive measures continue with undetermined effects on physical and mental health. Aims To compare child adolescent health services (CAMHS) referrals over 11 months (January–November) in 2020, 2018 examine any impact different phases COVID-19 restrictions might have referral rates. Method Monthly CAMHS Health Service Executive data were examined, covering...
ABSTRACT Post‐traumatic stress disorder (PTSD) is a highly debilitating condition that develops after trauma exposure. Dysregulation in extinction memory consolidation (i.e., the ability to remember trauma‐related stimuli no longer signal danger) proposed underlie PTSD development. Disruptions rapid eye movement (REM) sleep are thought be key contributor this dysregulation, as REM suggested play vital role processing of emotional memories. While previous literature has investigated natural...
We examined whether the processing of words associated with distinct spatial locations automatically biases behavior toward these in space. In four experiments (Ns = 30, 34, 32, 32), participants were shown stimuli denoting objects typically upper and lower regions visual Experiment 1, categorized as man-made or natural by pressing one two vertically arranged keys. Reaction times faster for trials which response congruent stimulus-associated locations. 2 replicated stimulus-response...
To determine whether arousals that terminate obstructive events in sleep apnea (OSA) (1) induce hypocapnia and (2) subsequently reduce genioglossus muscle activity following the return to sleep.Thirty-one untreated patients with OSA slept instrumented staging electrodes, nasal mask pneumotachograph, end-tidal CO2 monitoring, intramuscular electrodes. End-tidal was monitored, respiratory were assigned an end-arousal change value (PETCO2 on last arousal breath minus each individual's...
Abstract Study Objectives Genioglossus (GG) after-discharge is thought to protect against pharyngeal collapse by minimizing periods of low upper airway muscle activity. How GG occurs and which single motor units (SMUs) are responsible for the phenomenon unknown. The aim this study was investigate genioglossal after-discharge. Methods During wakefulness, elicited 8–12 times in healthy individuals with brief isocapnic hypoxia (45–60 s 10% O2 N2) terminated a breath 100% O2. SMUs were...
Abstract Introduction High activity of the genioglossus muscle is thought to prevent/resolve upper airway collapse. The individual motor units that make up overall genioglossal typically fire with one five patterns: active only (IP) or at higher frequency (IT) during inspiration; (EP) expiration (ET); and constantly without respiratory modulation (TT). Most experimental manipulations investigated thus far (hypoxia, hypercapnia, resistive loading sleep onset/arousal) have largely influenced...
Obstructive sleep apnea (OSA) is less prevalent among women and associated with different symptoms consequences to OSA in men. The reasons for these differences are unknown difficult tease apart clinical populations. If could be temporarily induced healthy men women, the causes of some investigated. Nasal blocking has been used induce but its effect not reported.A total 14 individuals (10 women) underwent in-laboratory diagnostic studies on two occasions separated by a week. On one occasion,...
Transient arousal from sleep has been shown to elicit a prolonged increase in genioglossus muscle activity that persists following the return and which may protect against subsequent airway collapse. We hypothesized this increased genioglossal after an is due persistent firing of inspiratory-modulated motor units (MUs) are recruited during arousal. Thirty-four healthy participants were studied overnight while wearing nasal mask with pneumotachograph measure ventilation 4 intramuscular EMG...