A5061797566- DNA and Nucleic Acid Chemistry
- Heat transfer and supercritical fluids
- Petroleum Processing and Analysis
- Thermochemical Biomass Conversion Processes
- Synthesis and Biological Evaluation
- Cancer therapeutics and mechanisms
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Catalysis for Biomass Conversion
- Solid-state spectroscopy and crystallography
- Advanced Chemical Sensor Technologies
- Mineral Processing and Grinding
- Advanced Combustion Engine Technologies
- Biodiesel Production and Applications
- Acoustic Wave Resonator Technologies
- X-ray Diffraction in Crystallography
University of the Pacific
2018-2024
Chevron (United States)
2019-2023
Chevron (Netherlands)
2012
We examined the chemical composition and properties of several diesel fuels blendstocks derived from Fischer–Tropsch (FT) synthesis, hydroisomerization lipids, fermentation sugar via terpenoid metabolic pathway. Comprehensive two-dimensional gas chromatographic analysis with nonpolar polar columns, 13C NMR, GC-MS, elemental were used to assess fuel chemistry. Performance included density, heat combustion, cetane number, cloud point, as well other properties. The consisted almost entirely...
Statistical analysis of electrospray ionization (ESI) high-resolution accurate-mass (HRMS) liquid chromatography/mass spectrometry (LC/MS) data offers a method to study the molecular origin jet fuel thermal oxidative stability issues as measured by ASTM D3241 (Standard Test Method for Thermal Oxidation Stability Aviation Turbine Fuels). It is important understand this type processing and how appropriately use it technique. In work, Mass Profiler Professional (MPP, Agilent) used analyze ESI...
Abstract In this paper, we report the synthesis of a phenanthroline and neomycin conjugate ( 7 ). Compound binds to human telomeric G‐quadruplex G1 ) with higher affinity compared its parent compounds (phenanthroline neomycin), which is determined by several biophysical studies. shows good selectivity for (G4) DNA over duplex DNA. The binding predominantly enthalpy‐driven, stoichiometry one tight‐binding event as ESI mass spectrometry. A plausible mode synergistic effect end‐stacking groove...
In the field of drug development, quest for novel compounds that bind to DNA with high affinity and specificity never ends. present work, we report newest development in this field, namely, triplex DNA-specific binding ligands based on 5-substituted flavone scaffold our lab. Biophysical studies showed newly synthesized derivatives (depending side chains) affinities better than or similar 3,3′,4′,7-tetramethoxyflavonoids. These selectively stabilize while having little effect duplex DNA, as...