A5012567261- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Plant biochemistry and biosynthesis
- Molecular Biology Techniques and Applications
- Plant Gene Expression Analysis
- Nitrogen and Sulfur Effects on Brassica
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mindfulness and Compassion Interventions
- COVID-19 and Mental Health
- Natural product bioactivities and synthesis
- Ovarian function and disorders
- Cancer Risks and Factors
- Metabolomics and Mass Spectrometry Studies
- Tannin, Tannase and Anticancer Activities
Zhongkai University of Agriculture and Engineering
2024
Tongji University
2022-2023
Shanghai Tenth People's Hospital
2022-2023
China University of Geosciences
2023
Abstract Background Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used treatment improve hormone secretion. However, the long-term HRT increases risk of breast cancer and cardiovascular disease are attracting concerns. Therefore, there urgent need develop safe effective for POF. Method Adipose-derived stem cells (ADSCs) were isolated...
As a common complication of epithelial ovarian cancer (EOC), malignant ascites contributes to the peritoneal metastasis EOC. CircRNAs play essential roles in tumor metastasis. However, no circRNAs have been reported be involved EOC via ascites.Total 22 samples from 9 patients containing primary lesions (T), cells (ASC), and metastatic (M) were included for RNA sequencing identify differentially expressed mRNAs among different tumors. Bioinformatic analyses, including single-sample Gene Set...
Abstract China possesses abundant species resources in genus Lithocarpus Blume, commonly known as “acorns.” These nuts are traditional foods China, holding significant potential for local specialty food and rural economic development. To explore their edible value, we compared the nutritional components metabolites between fruits of corneus (YD) pachylepis (HL), which cultivated widely south China. Non‐targeted metabolomics analysis YD HL was performed using ultra‐performance liquid...
Ovarian reserve (OR) is mainly determined by the number of primordial follicles in ovary and continuously depleted until ovarian senescence. With development assisted reproductive technology such as tissue cryopreservation autotransplantation, growing demand has arisen for objective assessment OR at histological level. However, no specific biomarkers can be used effectively clinic nowadays. Herein, bulk RNA-seq datasets murine with biological age (BOA) dynamic changes single-cell different...
Camellia drupifera is mainly used in forestry for its high-value industrial products; however, limited information available on transcriptome. This study aimed to construct a full-length transcriptome sequence based the PacBio sequencing platform various plant parts of C. drupifera, including flower buds, leaves, leaf branches, pericarp, and seed kernels. The transcriptomes were annotated with 23,207 genes, 58 subgroups GO classification. KEGG database revealed 10,407 genes involved...
Efficient evaluation of the primordial follicle pool (PFP) mammalian models is an essential subject in biomedical research relating to ovarian physiology and pathogenesis. Our recent study has identified a gene signature including Sohlh1, Nobox, Lhx8, Tbpl2, Stk31, Padi6, Vrtn strongly correlated with reserve by using bioinformatics analysis. Aimed investigate validity these candidate biomarkers for evaluating PFP, we utilized OR comparison model decode relationship between numbers PFP...
Abstract Purpose As a common complication of epithelial ovarian cancer (EOC), malignant ascites contribute to the peritoneal metastasis EOC. CircRNAs play essential roles in tumor metastasis. However, no circRNAs have been reported be involved EOC via ascites. Methods Total 22 samples from 9 patients containing primary lesions (T), cells (ASC), and metastatic (M) was included for RNA sequencing identify differentially expressed mRNAs among different tumors. Bioinformatic analyses, including...
Abstract Efficient evaluation of the primordial follicle pool (PFP) mammalian models is an essential subject in biomedical research relating to ovarian physiology and pathogenesis. Our recent study has identified a gene signature including Sohlh1 , Nobox Lhx8 Tbpl2 Stk31 Padi6 Vrtn strongly correlated with reserve by using bioinformatics analysis. Aimed investigate validity these candidate biomarkers for evaluating PFP, we utilized OR comparison model decode relationship between numbers PFP...