A5034371048- Chronic Myeloid Leukemia Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Lymphocytic Leukemia Research
- Pharmacovigilance and Adverse Drug Reactions
- Childhood Cancer Survivors' Quality of Life
- Pharmaceutical Practices and Patient Outcomes
- Statistical Methods in Clinical Trials
- Lymphoma Diagnosis and Treatment
- Cancer survivorship and care
- Lung Cancer Treatments and Mutations
- Economic and Financial Impacts of Cancer
- Asthma and respiratory diseases
- Parkinson's Disease Mechanisms and Treatments
- Atrial Fibrillation Management and Outcomes
- Multiple Myeloma Research and Treatments
- Cardiac electrophysiology and arrhythmias
- Neurological disorders and treatments
- Global Health Care Issues
- Polyomavirus and related diseases
- Botulinum Toxin and Related Neurological Disorders
- Cancer Treatment and Pharmacology
- Chemotherapy-induced cardiotoxicity and mitigation
- Colorectal Cancer Treatments and Studies
- Cancer-related cognitive impairment studies
- HER2/EGFR in Cancer Research
Centre d’Investigation Clinique 1436
2017-2024
Centre Hospitalier Universitaire de Toulouse
2018-2024
Université Toulouse III - Paul Sabatier
2016-2023
Université de Toulouse
2017-2023
Inserm
2017-2023
Hôpital Purpan
2020-2023
Pharmacochimie et Pharmacologie pour le Développement
2019-2021
Laboratoire Epidémiologie et Analyses en Santé Publique : Risques, Maladies Chroniques et Handicaps
2020-2021
Observatoire Midi-Pyrénées
2021
Agence Nationale de la Recherche
2018
Population-based data on the epidemiology of progressive multifocal leukoencephalopathy, its predisposing conditions and mortality rate are lacking, although such crucial to raise awareness among clinicians lay foundations for future therapeutic trials in immunomodulating therapies. In our study, patients were identified by interrogating French national healthcare reimbursement database from 1 January 2008 31 December 2017, using leukoencephalopathy International Classification Diseases code...
Abstract Objectives Medical biology is essential for diagnosing and monitoring cardio-reno-metabolic diseases. The EPI-CKD1 study utilizes data from Biogroup ® French laboratories to examine the burden of chronic kidney disease (CKD) effect heart failure, diabetes in an outpatient setting order address gaps national databases that lack biological data. Methods All adults (≥18 years) with at least one blood creatinine test between January 1st 2021, June 30th 2022 were included. Key biomarkers...
This study aimed to assess the performance of several algorithms based on hospital diagnoses and long-term diseases scheme identify multiple myeloma patients. Potential patients in 2010 2013 were identified using presence records with at least 1 main diagnosis code for (ICD-10 "C90"). Alternative also considered related associated diagnoses, combination conditions, or 2 diagnoses. Incident those no previous "C90" codes past 24 12 months. The sensitivity, specificity, positive negative...
We analyzed demographic characteristics, comorbidities and patterns of treatment with tyrosine kinase inhibitors (TKIs) in a cohort 3,633 incident cases chronic myeloid leukemia (CML) identified across France from 1 January 2011 to 31 December 2014. Patients were through specific algorithm the French Healthcare Data System followed up 12 months after inclusion cohort. The estimated incidence rate CML for this period was 1.37 per 100,000 person-years (95% Confidence Interval 1.36-1.38) higher...
Previous studies have suggested that lymphoma survivors commonly display altered Health-Related Quality of Life (HRQoL). Because these were predominantly cross-sectional studies, the dynamic events as well factors which influence HRQoL remain to be determined.We conducted a prospective study on cohort 204 Hodgkin and non-Hodgkin who remained disease-free 2 years after undergoing chemotherapy (referred M0-M12-M24 periods).We found although Physical Mental Component Scores (PCS MCS)...
In addition to the clinical burden, asthma is responsible for a high economic burden. However, little known about burden of prior death. We performed an analysis describe costs during 12 and 24 months death between 2013 2017 in France. An observational cohort study was established using French national health insurance database. Direct medical non-medical costs, as well related absence from workplace, were included analysis. total, 3,829 patients final Over death, total per patient €27,542...
Concomitant nonsteroidal anti-inflammatory drug (NSAIDs) and antithrombotic use is associated with an increased risk of bleeding, mainly gastrointestinal. The goal this study was to quantify the transient increase in hospitalization for bleeding NSAID patients treated antiplatelet agents or anticoagulants. We performed a unidirectional case-crossover using EGB (Échantillon généraliste de bénéficiaires), permanent random sample French nationwide health database. Patients receiving therapy...
Background: Lymphomas are costly diseases that suffer from a lack of detailed economic information, notably in real-world setting. Decision-makers increasing the search for Real-World Evidence (RWE) to assess impact, real-life, healthcare management and support their public decisions. Thus, we aimed net costs active treatment phases adult Hodgkin Lymphoma (HL), Follicular (FL) Diffuse Large B Cell (DLBCL).Methods: We performed retrospective cohort study using population-based data national...
The use of claims database to study lymphomas in real-life conditions is a crucial issue the future. In this way, it essential develop validated algorithms for identification these databases. aim was assess validity diagnosis codes French health insurance identify incident cases according results regional cancer registry, as gold standard. Between 2010 and 2013, were identified hospital data through 2 selection. process characteristics compared with from Tarn Cancer Registry. Each...
Abstract In adults, statins safety profile is well known. However, literature data on their adverse drug reactions (ADRs) remain scarce in children real‐life setting. order to better characterize ADRs related ‘real‐life’ use of children, we reviewed statin‐related recorded the World Health Organization (WHO) global database individual case reports (ICSRs), VigiBase. Methods. Individual (ICSRs) (2–11 years) and adolescents (12–17 associated with from January 1, 1987, July 18, 2017, were...
Abstract Psychotropic drugs (PD) are often used close to a cancer diagnosis and may be considered as way of coping. We aimed determine the incidence anxiolytics, hypnotics, antidepressants, antipsychotics initiation around chronic myelogenous leukemia (CML). Population‐based cohort: Data were extracted from Systeme National des données de Santé (SNDS, French health insurance database) at regional level (Midi‐Pyrenees area, 2.9 million inhabitants). All newly diagnosed patients treated by CML...
Patients suffering from B-cell non-Hodgkin lymphomas (B-NHL) have an increased likelihood of being exposed to proton pump inhibitors (PPIs), related several factors which been reported in the literature. PPIs are among drugs most likely be prescribed inappropriately. Consequently, B-NHL patients could particularly at risk inappropriate PPI prescription, with potential adverse drug reactions. We aimed evaluate incidence use and identify associated initiation during active treatment phase...
Infections are frequent and often result in serious complications patients with multiple myeloma (MM). Prophylactic vaccination is recommended for influenza virus, Streptococcus pneumoniae (SP), Hemophilus influenzaeb (Hib). The aims of this study were to measure the rates within 24 months after diagnosis identify factors associated vaccine use. MM selected through French national health insurance database from 1 January 2010 31 December 2015. Patients a previous history excluded....