Lei Jin

ORCID: 0000-0002-7811-4089
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Asymmetric Synthesis and Catalysis
  • Enzyme function and inhibition
  • Asymmetric Hydrogenation and Catalysis
  • Supercapacitor Materials and Fabrication
  • Silk-based biomaterials and applications
  • Calcium Carbonate Crystallization and Inhibition
  • ZnO doping and properties
  • Catalysis and Hydrodesulfurization Studies
  • Synthetic Organic Chemistry Methods
  • biodegradable polymer synthesis and properties
  • Catalytic Processes in Materials Science
  • Lung Cancer Treatments and Mutations
  • Chemical Synthesis and Reactions
  • Chronic Lymphocytic Leukemia Research
  • PI3K/AKT/mTOR signaling in cancer
  • Radiopharmaceutical Chemistry and Applications
  • Electrospun Nanofibers in Biomedical Applications
  • Crystallography and molecular interactions
  • Advancements in Battery Materials
  • Axial and Atropisomeric Chirality Synthesis
  • Multicomponent Synthesis of Heterocycles
  • Microbial Applications in Construction Materials

Huangshan University
2022

Guangdong Food and Drug Vocational College
2019

Inframat Corporation (United States)
2006

MnO2 nanofiber was found to possess high adsorption capacities for heavy metal ions such as, arsenic and lead, in water due its specific surface area (SSA) activity. However, a significant amount of manganese leach from nanofibers. Reducing dissolution is very important improving applications drinking treatment. In this study, doped with Fe3+ reduce water. Dissolution tests were conducted on un-doped Fe-doped The results revealed that doping significantly reduced dissolution. SSA defects...

10.1016/j.stam.2006.09.010 article EN cc-by-nc Science and Technology of Advanced Materials 2006-11-21

Brigatinib and brigatinib-analog are potent selective ALK inhibitors with the similar structure. A simple sensitive high-performance liquid chromatography tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of brigatinib in rat plasma brain homogenate was developed validated. Chromatographic separation carried out on an ODS column acetonitrile 0.1% formic acid water as mobile phase gradient elution at a flow rate 0.5 mL/min. Detections were performed using TSQ Quantum...

10.1155/2019/9028309 article EN International Journal of Analytical Chemistry 2019-12-05

This paper demonstrates the Pd-catalyzed asymmetric allylic alkylation of 2-substituted cycloalkenyl carbonates using a chiral diaminophosphine oxide. With this catalyst system, corresponding products were obtained in excellent yields and high enantioselectivities. Furthermore, authors described transformations reaction adducts to heterobicycles with quaternary carbon center.

10.1055/s-2008-1078556 article EN Synfacts 2008-07-23

Several methods for asymmetric allylic alkylation exist which can introduce various nucleophiles such as nitrogen, sulfur and oxygen. This reaction is often plagued by side reactions or multiple alkylations. The authors describe the of nitromethane show its use in synthesis two natural products.

10.1055/s-2006-949495 article EN Synfacts 2006-11-23

Abstract: A new process that could efficiently prepare tetrasubstituted bis(3-indolyl)methanes from various indoles and acetophenones with 1,3-Dibromo-5,5-dimehtylhydantoin(DBDMH) as a catalyst was reported. The effects of catalysts, solvents, reaction temperature were investigated. Under the optimal condition, most obtained in 90–99% yields.

10.2174/1570178619666220111122536 article EN Letters in Organic Chemistry 2022-01-13
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