Hao Wu

ORCID: 0000-0002-7824-2021
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About
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Research Areas
  • Anesthesia and Sedative Agents
  • Intensive Care Unit Cognitive Disorders
  • Multicomponent Synthesis of Heterocycles
  • Cardiac, Anesthesia and Surgical Outcomes
  • Eicosanoids and Hypertension Pharmacology
  • Microwave-Assisted Synthesis and Applications
  • Innovative concrete reinforcement materials
  • Nitric Oxide and Endothelin Effects
  • Photoreceptor and optogenetics research
  • Peptidase Inhibition and Analysis
  • Neural dynamics and brain function
  • Geotechnical Engineering and Soil Stabilization
  • Neuroscience and Neuropharmacology Research
  • Innovations in Concrete and Construction Materials
  • Crop Yield and Soil Fertility
  • Asphalt Pavement Performance Evaluation
  • Biotin and Related Studies
  • Alcohol Consumption and Health Effects
  • Chemical Synthesis and Analysis
  • Chromium effects and bioremediation
  • Geotechnical Engineering and Underground Structures
  • Receptor Mechanisms and Signaling
  • Anesthesia and Pain Management
  • Helminth infection and control
  • Biochemical Acid Research Studies

Yangzhou University
2001-2024

Affiliated Hospital of Nantong University
2024

Nantong University
2024

University of California, Davis
2018

UC Davis Comprehensive Cancer Center
2018

Qingdao University of Technology
2010

Miami University
1996

Ribulose–1,5–bisphosphate carboxylase/oxygenase (Rubisco) is the rate–limiting enzyme for photosynthesis. Rubisco activase (RCA) can regulate activation state, influencing activity and photosynthetic rate. We obtained transgenic maize plants that overproduced rice RCA (OsRCAOE) evaluated photosynthesis in these by measuring gas exchange, energy conversion efficiencies photosystem (PS) I PSII, state. The OsRCAOE lines showed significantly higher initial net rate, PSII photochemical quantum...

10.3390/plants12081614 article EN cc-by Plants 2023-04-11

Inspired by previously discovered enhanced analgesic efficacy between soluble epoxide hydrolase (sEH) and phosphodiesterase 4 (PDE4) inhibitors, we designed, synthesized characterized 21 novel sEH/PDE4 dual inhibitors. The best of these displayed good in vitro assays. Further pharmacokinetic studies a subset four selected compounds led to the identification bioavailable inhibitor N-(4-methoxy-2-(trifluoromethyl)benzyl)-1-propionylpiperidine-4-carboxamide (MPPA). In lipopolysaccharide induced...

10.1021/acs.jmedchem.7b01804 article EN Journal of Medicinal Chemistry 2018-04-03

Abstract Background Dexmedetomidine has controversial influence on cardiac electrophysiology. The aim of this study was to explore the effects dexmedetomidine perioperative electrophysiology in patients undergoing general anesthesia. Methods Eighty-one were randomly divided into four groups: groups D 1 , 2 3 receiving 1, 0.5 μg/kg over 10 min and 0.5, μg/kg/h continuous infusion respectively, control group (group C) normal saline. Twelve-lead electrocardiograms recorded at time before...

10.1186/s12871-022-01811-5 article EN cc-by BMC Anesthesiology 2022-08-25

Benzoic acid or p-hydroxybenzoic undergoes rapid reaction with alcohol using H2SO4 as catalyst at normal pressure, under irradiating continuously of the 1 GHz and 50 mW microwave for 22–60 minutes to afford aromatic esters in 76–90%yields.

10.1081/scc-100105121 article EN Synthetic Communications 2001-01-01

Low density of electroencephalogram alpha band power was reported to be associated with perioperative cognitive dysfunction. Few studies have conducted explore the effects remimazolam on intraoperative frontal spectrum in older adults. Here, we aimed impact brain wave activity and postoperative function adults undergoing lower extremity fractures surgeries. Patients elective general anesthesia for fracture surgery were randomly allocated group (Group R) midazolam M). Group R induced bolus...

10.2147/cia.s496437 article EN cc-by-nc Clinical Interventions in Aging 2024-12-01

Rocuronium intravenous pain is common in induction of general anesthesia. The aim our study was to determine the median effective dose (ED50) prophylactic remifentanil for prevention rocuronium injection and explore effect age on ED50.Eighty-nine adult patients undergoing elective anesthesia, ASA I or II, regardless gender weight, were stratified according age: group R1 18-44 years, R2 45-59 R3 60-80 years. initial before set at 1 μg/kg lean body weight (LBW). doses adjusted degree using...

10.1007/s40122-023-00490-5 article EN cc-by-nc Pain and Therapy 2023-03-08

Pharmacokinetics of ivermectin in Carassius auratus was studied following a single oral or intramuscular administration at dose 0.4 mg/kg.After these two different routes,IVM concentration-time cruves most tissues C.auratus exhibited multi-peak phenomenon.After administration,non-compartmental pharmacokinetic parameters were as follows:Cmax=0.445 mg/L,Tmax=48 h,t1/2z=524.2 h,MRT(0-∞)=788 h and AUC(0-∞)=289.2(mg/L)·h.After follows:Cmax=0.264 mg/L,Tmax=8 h,t1/2z=153.9 h,MRT(0-∞)=269.78 h,and...

10.3724/sp.j.1231.2012.27581 article EN JOURNAL OF FISHERIES OF CHINA 2012-01-01

This article has been retracted by the publisher.

10.1109/iita-grs.2010.5603162 article EN 2010-08-01

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.200152071 article EN ChemInform 2001-12-25

A new type of precast lightweight aggregate concrete exterior wallboard is proposed in this study. It composed inner and outer panels, an insulation layer, concealed ribs. After adjusting the mixing ratio concrete, light weight, bearing capacity, good workability were guaranteed. The flexural performance composite was studied by testing numerical modeling four wallboards, results deflection, crack morphology, failure mode, ultimate capacity then obtained. Additionally, cracking bending...

10.1155/2022/1328583 article EN cc-by Advances in Civil Engineering 2022-01-01
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