A5033609457- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiomyopathy and Myosin Studies
- Aortic Disease and Treatment Approaches
- Antimicrobial Resistance in Staphylococcus
- Protein purification and stability
- Congenital Heart Disease Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Cardiac pacing and defibrillation studies
- Streptococcal Infections and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Hemodynamic Monitoring and Therapy
- Ultrasound in Clinical Applications
- Lysosomal Storage Disorders Research
- Cardiac electrophysiology and arrhythmias
- Mechanical Circulatory Support Devices
- Venous Thromboembolism Diagnosis and Management
Hôpital du Sacré-Cœur de Montréal
2014-2024
Université de Montréal
2014-2024
Centre Hospitalier Universitaire de Bordeaux
2022
University Hospital Complex Of Vigo
2022
Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona
2019
Toronto General Hospital
2013-2017
University of Toronto
2013-2017
University Health Network
2014-2015
Toronto Public Health
2013
Montreal Heart Institute
2011-2013
Background . Right ventricular (RV) dysfunction during cancer therapy related cardiotoxicity and its prognostic implications have not been examined. Aim We sought to determine the incidence value of RV at time LV defined cardiotoxicity. Methods retrospectively identified 30 HER2+ female patients with breast treated trastuzumab (± anthracycline) who developed had a diagnostic quality transthoracic echocardiography. ejection fraction (LVEF), fractional area change (RV FAC), peak systolic...
Background The aim of this study was to compare left ventricular ( LV ) remodeling using myocardial strain between patients with severe aortic stenosis AS treated transcatheter valve replacement TAVR and without prosthesis‐patient mismatch PPM ). Methods Results In a retrospective study, speckle‐tracking echocardiography used measure global longitudinal GLS rate GLSR ), circumferential strain, rotation before at mid‐term follow‐up post‐ . Moderate were defined as an effective orifice area...
Early discharge after transcatheter aortic valve replacement (TAVR) has been increasingly reported, and is now becoming routinely performed in experienced TAVR centers. However, to the best of our knowledge, no case described where a patient was safely discharged on same day procedure. This report will present who underwent successful transfemoral home day. Specific requirements criteria are proposed ensure safety this approach. © 2015 Wiley Periodicals, Inc.
Acute viral pneumonia, hypoxemic respiratory failure and severe inflammatory response are hallmarks of coronavirus disease 2019 (COVID-19). The COVID-19-associated state may further lead to symptomatic thromboembolic complications despite prophylaxis. We report a 66-year-old female patient with post-mortem diagnosis COVID-19 who presented progressive livedo racemosa, acute renal myocardial injury, as well an absence symptoms. Transthoracic echocardiography showed spontaneous echo contrast in...
In the interest of generating large amounts recombinant protein, inducible systems have been studied to maximize both growth culture and production foreign proteins. Even though thermo-inducible were developed in late 1970's, number studies that focus on strategies for implementation at bioreactor scale is limited. this work, bacteriophage lambda PL promoter once again investigated as an element but green fluorescent protein (GFP). Culture temperature, induction point, duration inductions...
Simpson biplane method and 3D by transthoracic echocardiography (TTE), radionuclide angiography (RNA) cardiac magnetic resonance imaging (CMR) are the most accepted techniques for left ventricular ejection fraction (LVEF) assessment. Wall motion score index (WMSI) TTE is an complement. However, conversion from WMSI to LVEF obtained through a regression equation, which may limit its use. In this retrospective study, we aimed validate new derive wall in 95 patients.The consisted of attributing...
Abstract Background Mitral annulus (MA) area is derived during transthoracic echocardiography (TTE) assuming of a circular shape using the MA diameter from apical 4 chamber (A4c) view. Since not structure, we hypothesized that an elliptical model parasternal long-axis (PLAX) and 2 (A2c) view measured diameters would have better agreement with 3-dimensional transesophageal (3D TEE) in degenerative mitral valve disease (DMVD). Methods Seventy-six patients moderate-to-severe DMVD had 2D TTE 3D...
Expanded bed adsorption (EBA) is an efficient protein purification process reducing time and steps of downstream processing (DSP) since nonclarified culture media can be processed directly without prior treatments such as filtration or centrifugation. However, cells debris interact with the adsorbent affect stability well performance. To optimize EBA operating conditions these biomass/adsorbent interactions have to understood characterized. The Human Embryonic Kidney (HEK 293) on unprimed...
<h3>Background</h3> As immunomodulatory therapies such as recombinant human interferon beta gain clinical applicability, patients are likely to experience some of their numerous cutaneous adverse effects at injection sites. We describe a case beta–induced septal panniculitis. <h3>Observations</h3> A 43-year-old woman with multiple sclerosis treated subcutaneous presented right lower abdominal quadrant pain, fever, and an indurated McBurney point. An computed tomographic scan showed...
Fabry disease (FD) is a lysosomal storage disorder caused by an enzymatic deficiency. Conduction abnormalities and bradyarrhythmias are common can occur prior to the onset of left ventricular (LV) hypertrophy. We aimed describe clinical, electrocardiographic echocardiographic, including atrial (LA) function, determinants bradyarrhythmic events in FD.Bradyarrhythmic frequent patients with FD associated LA dysfunction.We designed cross-sectional study that includes 53 (mean age, 45 years; 42%...
Patients with a small aortic annulus (≤21 mm) have an increased risk of patient-prosthesis mismatch after valve replacement. The aim this study was to compare the early hemodynamic performance balloon-expandable transaortic implantation Edwards system (SAPIEN) and sutureless Perceval prostheses.Fifty patients underwent transcatheter implantation, 113 Mean ± SD diameter 19.7 1 mm, no significant difference between groups. SAPIEN size 23 mm in 40 (80%) 26 10 (20%). 45 (40%), medium 62 (55%),...
Abstract Background There is a need for convenient, yet reliable method to assess left ventricular ejection fraction (LVEF) with point-of-care ultrasound study (POCUS). We aim validate novel and simplified wall motion score LVEF based on the analysis of combination echocardiographic views. Methods In this retrospective study, transthoracic echocardiograms randomly selected patients were analysed by standard 16-segments index (WMSI) derive reference semi-quantitative LVEF. To develop our...