A5005435547- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Phytochemical compounds biological activities
- Bone Tissue Engineering Materials
- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Inflammasome and immune disorders
- Estrogen and related hormone effects
- Cancer, Hypoxia, and Metabolism
- Plant-based Medicinal Research
- Bipolar Disorder and Treatment
- Pharmacological Effects of Natural Compounds
- Hypothalamic control of reproductive hormones
- Evaluation and Optimization Models
- Glioma Diagnosis and Treatment
- Ion Channels and Receptors
- Hormonal Regulation and Hypertension
- Dental Implant Techniques and Outcomes
- Ion Transport and Channel Regulation
- 3D Printing in Biomedical Research
- Retinal Diseases and Treatments
- Ion channel regulation and function
- Retinal and Macular Surgery
- dental development and anomalies
- Retinal and Optic Conditions
Fujian Medical University
2021-2023
Union Hospital
2022
First Affiliated Hospital of Xinjiang Medical University
2015-2017
Xinjiang Medical University
2015-2017
Huazhong University of Science and Technology
2013-2017
Suizhou Central Hospital
2015
South Central Minzu University
2012
Although early life stress (ELS) can increase susceptibility to adulthood psychiatric disorders and produce a greater inflammatory response in stressful event, targeted preventive therapeutic drugs still remain scarce. Ganoderma lucidum triterpenoids (GLTs) exert anti-inflammatory effects the periphery central nervous systems. This study employed combined model of "childhood maternal separation + sub-stress" explore whether GLTs may alleviate anxiety- depression-like behaviors male female...
Abstract Population-based studies reveal that apolipoprotein E ( APOE ) ε 4 gene allele is closely associated with late-life depression (LLD). However, its exact role and underlying mechanism remain obscure. The current study found aged apoE4-targeted replacement (TR) mice displayed obvious depression-like behavior when compared age-matched apoE3-TR mice. Furthermore, apoE4 increased stress-induced behaviors, accompanied by declines in the hippocampal 5-HT (1A) radioligand [18F] MPPF uptake...
Abstract Acidosis has been known to cause “Ca 2+ transients”, however, the mechanism is still uncertain. Here, we demonstrated that multiple H + sensors, such as ASICs, TRPV1 and proton-sensing G protein coupled receptors (GPCRs) are involved in extracellular acidification-induced intracellular calcium ([Ca ] i ) elevation. By using imaging measures, observed both ASIC channels inhibitors suppressed [Ca elevation induced by acidosis cultured rat cardiac myocytes. Then, mRNA proteins were...
Introduction: Gonadotropin-releasing hormone (GnRH) is a hypothalamic neuropeptide that plays important roles in the female fertility. Accumulating evidence suggests ERα present astrocytes of hypothalamus region essential for production GnRH. The display age-related senescence associated to oxidative stress induced by estrogen metabolites. However, it still unclear whether and how expression changes during astrocyte aging. Methods: Immunofluorescence was performed analyze gene levels...
Human facial morphology varies considerably among individuals and can be influenced by gene polymorphisms. We explored the effects of single nucleotide polymorphisms (SNPs) on features in Uygur youth population Kashi area Xinjiang, China. Saliva samples were collected from 578 volunteers, 10 SNPs previously associated with variations physiognomy genotyped. In parallel, 3D images subjects' faces obtained using grating scanning technology. After delimitation 15 salient landmarks, correlation...