A5047488663- Helicobacter pylori-related gastroenterology studies
- Pancreatic and Hepatic Oncology Research
- Metabolism, Diabetes, and Cancer
- Gastric Cancer Management and Outcomes
- Cancer, Lipids, and Metabolism
- RNA modifications and cancer
- Eosinophilic Esophagitis
- Ferroptosis and cancer prognosis
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Cancer, Hypoxia, and Metabolism
- Liver Diseases and Immunity
- Liver physiology and pathology
- Liver Disease Diagnosis and Treatment
- Bioinformatics and Genomic Networks
- Glutathione Transferases and Polymorphisms
- Colorectal Cancer Treatments and Studies
- Mycobacterium research and diagnosis
- Surgical site infection prevention
- Immunotherapy and Immune Responses
- Veterinary medicine and infectious diseases
- Surgical Sutures and Adhesives
- Hepatitis B Virus Studies
- Anesthesia and Pain Management
- Cancer Cells and Metastasis
Huzhou Central Hospital
2016-2024
Huzhou University
2021
Zhejiang University
2021
First Affiliated Hospital of Chengdu Medical College
2020
Pancreatic cancer is one of the most lethal cancers and its prognosis extremely poor. Clarification molecular mechanisms identification prognostic biomarkers are urgently needed. Though we previously found that LGMN was involved in pancreatic carcinoma progression, upstream regulation remains unknown. We used reliable software to search for potential transcription factors may be related with transcription, ELK1 could a new regulator binded directly promoter. Moreover, knocking down reduced...
GDP dissociation inhibitor (GDI) regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting dissociation. This study evaluated potential prognostic and predictive value GDI1 in colorectal cancer (CRC). To address power GDI1, we performed individual pooled survival analyses on six independent CRC microarray gene expression datasets. GDI1-enriched signatures were also analyzed. Kaplan–Meier Cox proportional employed for analysis. An immunohistochemistry (IHC) analysis was to...
This study combined network pharmacology, molecular docking, and in vitro experiments to explore the potential mechanism of active components n-butanol fraction Wenxia Formula(NWXF) with gefitinib(GEF) treating non-small cell lung cancer(NSCLC). Ultra-performance liquid chromatography-quadrupole Orbitrap mass spectrometry(UPLC-Q-Orbitrap MS) was employed detect main chemical NWXF. The NWXF were retrieved from SwissADME, candidate targets these SwissTargetPrediction. Online Mendelian...
To study the effects of estrogen receptor (ER) alpha gene polymorphism on migration T lymphocyte subsets and related cytokines in female patients with primary biliary cirrhosis(PBC).This was conducted sixty PBC without treatment as group fifty-two healthy people wtih sex age met requirements control group. The restriction enzyme cutting site Xba I Pvu II intron 1 ERa detected by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). CD4+, CD8+, CD4+CD25+ CD4+CD28-...
Objective To investigate the antibiotic resistance trend of commonly used antibiotics Helicobacter pylori (H. pylori) in Huzhou district, and to summarize efficacy eradication related digestive diseases. Methods In year 2009, 2013, 2014 2015, 8 139 gastric mucosa samples patients undergoing gastroendoscopy examination were collected H. strains isolated cultured. The situation levofloxacin, clarithromycin, metronidazole, amoxicillin, tetracycline furazolidone was analyzed. infection...
Objective To analyze the resistance to clarithromycin and levofloxacin by Helicobacter pylori (Hp) strains, explore related gene mutation, in order provide evidence for clinical treatment of eradicating Hp. Methods There were 136 Hp strains isolated from gastric mucosa biopsy specimens collected 267 gastritis patients Huzhou Central Hospital. Plate incorporation method was used determine resistance. genomic DNA extracted, mutation 2 142 143 loci V Region (variable region) 23S rRNA, as...
Objective To investigate and analyze the prevalence of Helicobacter pylori infection antibiotic resistance in patients different genders ages. Methods Helicobacter strains were isolated from gastric mucosa biopsy specimens, which collected 23 771 gastritis Huzhou Central Hospital Zhejiang September 2013 to December 2015. The was determined by plate incorporation method, statistical analysis performed on results drug sensitivity. Results There 9 106 specimens. positive rate...
Objective To investigate the prevalence of H.pylori (HP) infection and antibiotic resistance in symptomatic children adolescents Huzhou, Zhejiang. Methods HP strains were isolated from gastric mucosa biopsy specimens collected 391 at age 10-18 years old Huzhou Central Hospital January 2014 to June 2017. Plate incorporation method was used determine drug sensitivity. Results There 107 (27.37%) HP specimens. The positive rate with duodenal ulcer significantly higher than that ones...