A5089760238- Hungarian Social, Economic and Educational Studies
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Cell Adhesion Molecules Research
- Ethics and Social Impacts of AI
- European and International Law Studies
- Ombudsman and Human Rights
- Privacy, Security, and Data Protection
- Maritime Ports and Logistics
- SARS-CoV-2 and COVID-19 Research
- Complement system in diseases
- Hepatitis B Virus Studies
- Mesenchymal stem cell research
- Transportation Planning and Optimization
- Immune cells in cancer
- Cancer Cells and Metastasis
- CAR-T cell therapy research
- Cancer Immunotherapy and Biomarkers
- Digitalization, Law, and Regulation
- Hematopoietic Stem Cell Transplantation
- Viral Infections and Outbreaks Research
Bernhard Nocht Institute for Tropical Medicine
2025
Eötvös Loránd University
2015-2023
Semmelweis University
2016-2020
University of Pecs
2020
Hungarian Academy of Sciences
2016
Abstract This study shows that melanoma-associated fibroblasts (MAFs) suppress cytotoxic T lymphocyte (CTL) activity and reveals a pivotal role played by arginase in this phenomenon. MAFs normal dermal (DFs) were isolated from surgically resected melanomas identified as Melan-A-/gp100-/FAP+ cells. CTLs of healthy blood donors activated the presence MAF- DF-conditioned media (CM). Markers successful CTL activation, degranulation, killing immune checkpoint regulation evaluated flow cytometry,...
Abstract Dendritic cells connect innate and adaptive immune responses. This is a particularly important checkpoint in the case of emerging infections against which most population does not have preexisting antibody immunity. In this study, we sought to test whether antibody-based delivery Ebola virus (EBOV) antigens dendritic could be used as vaccination strategy disease. Our approach was use antibodies targeting endocytic receptor DEC-205 present murine human cells, deliver EBOV...
This study sought to identify novel CD8+ T cell homing markers by studying acute graft versus host disease (aGvHD), typically involving increased the skin and gut. FACS-sorted skin-homing (CD8β+ /CLA+ ), gut-homing /integrinβ7+ reference /CLA- /integrinβ7- ) cells were compared in patients affected cutaneous and/or gastrointestinal aGVHD. Microarray analysis, qPCR, flow cytometry revealed expression of peptidase inhibitor 16 (PI16) cells. Robust association PI16 with was confirmed all types...
<p>The Porto Metropolitan Area (Área Metropolitana do Porto, AMP) is a framework of cooperation between 17 municipalities and several districts. This metropolitan area has specific, inter-municipal model urban governance. In our research, we found that significant mainly in sectors where the central legislature essentially made this mandatory, by designing AMP defining its powers. addition to AMP, only partial been established field waste management, human public services performance...

 Napjainkban általánosan elfogadott, hogy nélkülözhetetlen a környezettel való tudatos, felelősségteljes bánásmód. Korunk államainak működését egyre inkább új dimenzióba helyezi legtágabb értelemben felfogott globalizáció jelensége. A globalizálódó és digitalizálódó világ sajátosságai, így egyebek mellett (kiber)terrorizmus fenyegető jelenléte, munkanélküliség vagy éppen járványok terjedése, migrációs folyamatok tömegessé válása az országokon átívelő környezetszennyezések olyan világot...
The study deals with the right to redress, and thus procedural guarantees of lawful functioning public administration, from a particular point view enforcement client rights. author, in general context study, begins by discussing requirement lawfulness then content appeal its requirements for law. Thereafter, system redress administrative procedure under new regulations will be introduced through processing laws on order litigation. At end conclusions drawn that address both relationship...
A fogyasztóvédelem – lévén anyagi joga a közjog és magánjog határán helyezkedik el két eszközrendszer felhasználásán keresztül törekszik fogyasztói jogok érvényesítésére: egyrészt végrehajtó hatalom részeként működő fogyasztóvédelmi intézményrendszer fenntartását működtetését, másrészt bírósági, illetve az extrajudiciális jogérvényesítés rendelkezésre bocsátását foglalja magába. Ebben tanulmányban „igazgatás” ki- átalakulását tesszük vizsgálat tárgyává, különös tekintettel azokra,...
Introduction Melanoma associated fibroblasts (MAFs) represent a highly heterogeneous population of fibroblast-like cells residing in the tumour stroma, exact origin which is matter ongoing debate. In many aspects, MAFs recapitulate key features both mesenchymal stem (MSCs) having well-known immunosuppressive properties, and activated actively participating matrix reorganisation, prerequisite invasion. Compared to normal fibroblasts, display high proliferation rate, show increased motility,...