A5004604240- Electroconvulsive Therapy Studies
- Treatment of Major Depression
- Stress Responses and Cortisol
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Perfectionism, Procrastination, Anxiety Studies
- Anesthesia and Sedative Agents
- Eating Disorders and Behaviors
- Tryptophan and brain disorders
- Child Abuse and Trauma
- Mental Health Research Topics
- Cardiac Health and Mental Health
- Electrolyte and hormonal disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Hormonal Regulation and Hypertension
- Transcranial Magnetic Stimulation Studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Sleep and related disorders
- Nerve injury and regeneration
- Neuroendocrine regulation and behavior
- Nutrition, Health and Food Behavior
- Obsessive-Compulsive Spectrum Disorders
- Healthcare Decision-Making and Restraints
- Early Childhood Education and Development
- Maternal Mental Health During Pregnancy and Postpartum
Centro de Investigación Biomédica en Red de Salud Mental
2020-2023
Universitat de Barcelona
2018-2023
Bellvitge University Hospital
2014-2023
Institut Català de la Salut
2016-2023
Institut d'Investigació Biomédica de Bellvitge
2015-2023
Instituto de Salud Carlos III
2021-2022
Centro de Investigación Biomédica en Red
2022
Hospital Universitari Sagrat Cor
2020
Abstract Recent research suggests that neuroplastic and neuroinflammatory changes may account for the mode of action electroconvulsive therapy (ECT), although extant data do not allow a clear disambiguation between these two hypotheses. Multimodal neuroimaging approaches (for example, combining structural metabolic information) help in clarifying this issue. Here we aimed to assess longitudinal (i) regional gray matter (GM) volumes (ii) hippocampal metabolite concentrations throughout an...
Brain-derived neurotrophic factor (BDNF) gene regulation has been linked to the pathophysiology of major depressive disorder (MDD). MDD patients show cognitive deficits, and altered BDNF a relevant role in neurocognitive functions. Our goal was explore association between genetic epigenetic variations with performance group healthy controls considering possible modulating factors. The sample included 134 subjects, 64 patients, 70 controls. Clinical data, childhood maltreatment, were assessed...
Sleep plays a crucial role in cognitive processes. and wake memory consolidation seem to be regulated by glucocorticoids, pointing out the potential of hypothalamic-pituitary-adrenal (HPA) axis relationship between sleep quality abilities. Trait anxiety is another factor that likely moderate cognition, because poorer subtle HPA abnormalities have been reported people with high trait anxiety. The current study aimed explore whether activity or abilities healthy individuals. We studied 203...
Although there is scientific evidence of the presence immunometabolic alterations in major depression, not all patients present them. Recent studies point to association between an inflammatory phenotype and certain clinical symptoms with depression. The objective our study was classify depression disorder using supervised learning algorithms or machine learning, based on oxidative stress biomarkers lifestyle habits.
Few systematic evaluations have been performed of the efficacy electroconvulsive therapy (ECT) as a relapse prevention strategy in major depressive disorder (MDD). This is single-blind, multicenter, randomized controlled trial to compare and tolerability pharmacotherapy plus maintenance ECT (M-Pharm/ECT) versus alone (M-Pharm) MDD relapse. Subjects with who had remitted bilateral acute (n = 37) were randomly assigned receive M-Pharm/ECT 19, 14 treatments) or M-Pharm 18) for nine months. The...
In electroconvulsive therapy (ECT), ictal characteristics predict treatment response and can be modified by changes in seizure threshold the ECT technique. We aimed to study impact of procedure-related variables that interact during each session might influence results. Two hundred fifty sessions bilateral forty-seven subjects were included. Seizure results evaluated two different scales combined EEG parameters (seizure quality index (SQI) adequacy markers sum (SAMS) scores) postictal...
Alterations in cognitive performance have been described patients with major depressive disorder (MDD). However, the specific risk factors of these changes are not yet known. This study aimed to explore whether inmunometabolic parameters related MDD comparison healthy controls (HC) METHODS: Sample consisted 84 and 78 HC. Both groups were compared on results measured Cambridge Neuropsychological Test Automated Battery (CANTAB), presence metabolic syndrome (MetS) an inflammatory/oxidative...
ABSTRACT Electroconvulsive Therapy (ECT) has been demonstrated to be a safe and effective treatment for geriatric depression, although its application might challenging when medical comorbidities exist. The present case reports 78-year-old man diagnosed with recurrent unipolar major depressive disorder (MDD), who presented severe episode psychotic features (DSM IV). He successfully received course of bitemporal (BT) ECT hip-aztreonam-spacer due hip fracture that occurred during...
Background: Childhood maltreatment (CM) is associated with impaired hypothalamic-pituitary-adrenal (HPA) axis negative feedback and cognitive dysfunction, resembling those abnormalities linked to major depressive disorder (MDD). Objectives: We aimed assess the potential modulating effects of MDD diagnosis or HPA function in association between different types CM performance adulthood. Methods: Sixty-eight patients 87 healthy controls were recruited. was assessed Trauma Questionnaire....
Relationships among childhood maltreatment (CM), hypothalamic-pituitary-adrenal (HPA) axis disturbances, major depressive disorder (MDD), poor functionality, and lower quality of life (QoL) in adulthood have been described. We aimed to study the roles remission status depression HPA function relationships between CM functionality QoL. Ninety-seven patients with MDD 97 healthy controls were included. The cortisol awakening response, suppression ratio dexamethasone test, diurnal slope...
Purpose: Airway management is a key objective in adapted electroconvulsive therapy (ECT) protocols during the COVID-19 pandemic to prevent infection. The of this study was describe effectiveness modified ventilation procedure designed reduce aerosol-generating bag-mask (BMV) and isolate possible droplets while maintaining adequate respiratory gas values ECT sessions. Materials Methods: This prospective analyzed results protocol applied over month. Adaptations entailed preoxygenation...
de Arriba-Arnau, Aida MD; Dalmau Llitjos, Antònia PhD; Soria, Virginia Menchón, José Manuel Urretavizcaya, Mikel PhD Author Information
Introduction Psychotic depression has a higher rate of disability and relapse than non psychotic depression, however the optimal maintenance treatment after an acute response to either antidepressant/antipsychotic combination or ECT course is unclear (Rothschild, 2013). Although effective therapy in affective disorders M/C used achieve maintain patient's stability (Brown, 2014), very little known about its implications functionality quality life. Objectives To study relation between symptoms...