A5022826941- COVID-19 Clinical Research Studies
- Muscle and Compartmental Disorders
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Disaster Response and Management
- Pancreatitis Pathology and Treatment
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Clinical Nutrition and Gastroenterology
- Dialysis and Renal Disease Management
- Nursing Diagnosis and Documentation
- SARS-CoV-2 and COVID-19 Research
- Nutrition and Health in Aging
- Nosocomial Infections in ICU
- Climate Change and Health Impacts
- Traumatic Ocular and Foreign Body Injuries
- Liver Disease Diagnosis and Treatment
- Cholinesterase and Neurodegenerative Diseases
- Chronic Kidney Disease and Diabetes
- Electrolyte and hormonal disorders
- Pharmacological Receptor Mechanisms and Effects
- Pneumocystis jirovecii pneumonia detection and treatment
- Enhanced Recovery After Surgery
- PARP inhibition in cancer therapy
- Vagus Nerve Stimulation Research
Sağlık Bilimleri Üniversitesi
2022-2025
Kayseri Eğitim ve Araştırma Hastanesi
2022-2025
Ministry of Health
2010-2025
Ministry of Health of the Russian Federation
2024
Erciyes University
2021-2024
Gaziantep University
2024
Kayser (Italy)
2023
State Hospital
2023
University of Health Science
2023
Zübeyde Hanim Maternity Hospital
2010
Various scoring systems and cytokines have been cited as predicting disease severity in COVID-19 infection. This study analyzed the link between mortality rate, levels of cytokines, such Glasgow Coma Scale (GCS), Acute Physiologic Assessment Chronic Health Evaluation II (APACHE II), Sequential Organ Failure (SOFA), Charlson Comorbidity Index patients infected with COVID-19. Adult were followed up intensive care unit (ICU) prospectively. We measured serum cytokine (Interleukin-10 (IL-10),...
Background and Objectives: The use of additional biomarkers to predict clinical course in diabetic ketoacidosis (DKA) is becoming increasingly important. aim this study was investigate the relationship between interleukin-6 (IL-6) levels length stay intensive care unit (ICU) patients with DKA without signs infection neutrophil–lymphocyte ratio (NLR) C-reactive protein (CRP) albumin (CAR). Materials Methods: This retrospective, single-center included 78 who were treated Medical ICU July 2022...
Background: On February 6, 2023, an earthquake occurred in Kahramanmaras, Turkey, resulting loss of life, injuries, and the displacement thousands people. The aim this study is to determine factors affecting amputation fasciotomy decisions patients with crush syndrome, along clinical laboratory parameters. Materials methods: included over 18 years age who presented injuries exhibited systemic symptoms. Inclusion criteria comprised creatine kinase (CK) levels exceeding 1,000 IU/L, oliguria...
Abstract Background On February 6, 2023 a devastating earthquake hit the south-eastern region of Türkiye and thousands people were either injured or died. The aim was to determine characteristics, treatment clinical outcomes critically ill patients with crush injuries in ICU. Subjects/methods This study performed retrospective design Patients included as follows; effected 6 earthquake, need ICU being syndrome. Results A total 62 included. mean age 41 ± 19 years 47% male. median APACHE II...
Background and Purpose: Candidemia remained important in the intensive care units (ICU) during COVID-19 pandemic. This study aimed to investigate clinical laboratory data on candidemia patients. Materials Methods: The baseline characteristics, as well findings of non-candidemia patients, were compared. was defined isolation Candida spp. from blood cultures. isolates identified by VITEK® 2 (bioMérieux, France) commercial method. Antifungal susceptibility assessed using E-test Univariate...
Gastrointestinal (GI) dysfunction is common in the intensive care unit (ICU), although there no consensus on biomarkers of GI dysfunction. We aimed to evaluate ultrasound-based gastric antrum measurements and serum intestinal fatty acid-binding protein (IFABP) citrulline levels relation critically ill patients.Adult patients receiving enteral nutrition stayed for ICU ≥48 h was included. described using Dysfunction Score (GIDS). Gastric measurements, including craniocaudal (CC) diameter,...
Patients with severe acute respiratory distress syndrome (ARDS) have high mortality rates; therefore, new biomarkers are necessary to predict the prognosis in early stages. Serum lactate dehydrogenase (LDH) level is a specific marker of lung damage, but it not sensitive because affected by several factors. This study aimed determine whether LDH/albumin ratio could be used as prognostic biomarker patients ARDS due COVID 19.Tertiary intensive care unit (ICU) and confirmed COVID-19 diagnosis...
Objective One of the most common causes mortality and morbidity in elderly patients is sepsis. Malnutrition widespread patients, affecting morbidity. The present study aimed to evaluate clinical features hospitalized tertiary intensive care unit with diagnosis sepsis, as well effects Sequential Organ Failure Assessment (SOFA) score, prealbumin, albumin, other laboratory parameters on hospital mortality. Methods were divided into two groups according their survival. demographic...
Abstract Background Acute respiratory distress syndrome(ARDS) due to COVID-19 is accompanied by severe hypoxemia and hyperinflammation. Hypoxia-inducible factor(HIF) pathway plays a fundamental role in detecting hypoxia developing appropriate responses. The epidemiological report claimed lower rate of disease the population living at high altitudes hypothesized that adaptation might be advantageous for SARS-CoV-2 infection. This study was designed examine frequency polymorphisms HIF-1α...
Introduction Familial Mediterranean fever (FMF) is a recessively inherited disease characterized by recurrent attacks of and sterile polyserositis. Recently, some proteins originating from adipose tissue have been demonstrated to play critical role in the inflammatory process. Asprosin new adipokine secreted tissue, proinflammatory cytokines determined increase with decrease circulating asprosin. This study was designed evaluate level asprosin acute attack attack-free period FMF patients....
The WHO emphasized the importance of knowing risk factors for severity disease in COVID-19 pandemic. Our aim this study was to determine relationship between serum Butyrylcholinesterase (BChE) level, which is rapidly affected by inflammation, and pneumonia mortality.Patients diagnosed with March May 2021 were included study. patients divided into two groups as severe mild moderate according WHO's guidelines. Serum BChE levels studied ELISA method from blood samples taken on day...
<title>Abstract</title> Background On February 6, 2023 a devastating earthquake hit the south-eastern region of Turkey. It is caused thousands people injury and dead. The aim was to determine characteristics, treatment clinical outcomes critically ill patients with crush injuries in ICU. Subjects/methods: This study performed retrospective design Patients were included as follows; effected 6 earthquake, need ICU being syndrome. Results A total 62 included. mean age 41 ± 19 years 47% male....
Abstract Background Peritoneal fibrosis (PF) is a major, persistent complication of prolonged peritoneal dialysis that eventually leads to ultrafiltration failure and termination dialysis. Prolonged exposure high glucose concentrations, degradation products, uremic toxins, episodes peritonitis can cause some changes in the membrane, resulting intraperitoneal inflammation PF, leading CA‐125 be used as biomarker mesothelial cell count dialysate for monitoring PD patients. Hypoxia‐inducible...
Carbon monoxide (CO) poisoning is a common occurrence, typically resulting from exposure to CO emissions in enclosed spaces. colorless, odorless, and tasteless gas. In this case report, we present 52-year-old male patient who developed crush syndrome acute kidney injury following carbon intoxication. The was found at home with loss of consciousness seizures brought the emergency department. A diagnosis made, treated hyperbaric oxygen therapy supportive care. clinical course, treatment...
Background This study aimed to investigate the effects of serum high mobility group box-1 (HMGB1), interleukin (IL)-6, IL-8, IL-1β, IL-10, and tumor necrosis factor alpha (TNF-α) levels on disease severity mortality in Crimean-Congo hemorrhagic fever (CCHF) patients. Materials methods was performed prospectively intensive care unit (ICU) infection ward a tertiary hospital Republic Türkiye. Patients aged 18 years older diagnosed with CCHF were included. Results Our included 30 patients, whom...
Asprosin, a new adipokine, is secreted by subcutaneous white adipose tissue and causes rapid glucose release. The skeletal muscle mass gradually diminishes with aging. combination of decreased critical illness may cause poor clinical outcomes in critically ill older adults. To determine the relationship between serum asprosin level, fat-free mass, nutritional status adult patients, patients over age 65 receiving enteral nutrition via feeding tube were included study. patients’...
Background and Aim:The new type of Severe Acute Respiratory Syndrome Coronavirus 2 (Coronavirus 2019-COVID-19) infection is the largest pandemic in last decade.Acute respiratory distress syndrome complication with highest mortality rate this there no adequate treatment proven efficacy to reduce mortality.This multi-center, retrospective study aimed determine effect high-dose vitamin C on survival other endpoints invasively ventilated ARDS patients.Methods: This observational cohort was...
Background Peritoneal dialysis patients are malnourished due to loss of protein in the dialysate and inadequate dialysis, although they take additional calories every day during treatment. Many parameters used assess nutritional status, with normalized catabolic rate (nPCR) being one most common. Asprosin, a novel adipokine secreted by adipose tissue, peaks fasting induces hepatic glucose release through activation G-protein-cAMP-PKA pathway, which has been indicated have curative effect on...
"Caesarean delivery rates in Turkish adolescents." Journal of Obstetrics and Gynaecology, 30(6), pp. 594–596
Purpose: The aim of this study; to evaluate the effects diaphragm thickness on weaning with ultrasonography (USG).
 Materials and Methods: In prospective demographic characteristics patients, indications for hospitalization in intensive care unit mechanical ventilation, comorbidity, thickness, Sequential Organ Failure Assessment (SOFA) score Simplified Acute Physiology Score (SAPS) II, mortality rate, peripheral oxygen saturation (SpO2), invasive ventilator (IMV) duration, minute...
Abstract Background Organ transplantation reduces mortality and morbidity in patients with end-stage organ failure. The number of living donations is not enough to meet the current need; therefore, there an urgent need for donation from cadavers. We aimed determine rates reveal obstacles against donation. Methods This study designed as a retrospective multicenter consisting eight university hospitals, three training research 26 state 74 private hospitals nine provinces Turkey. A total 1,998...