- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Olfactory and Sensory Function Studies
- Magnesium in Health and Disease
- Sleep and Wakefulness Research
- Neuroscience of respiration and sleep
- Botulinum Toxin and Related Neurological Disorders
- Diet and metabolism studies
- Suicide and Self-Harm Studies
- Psychosomatic Disorders and Their Treatments
Luigi Sacco Hospital
2017-2025
To evaluate the 1-year effectiveness and tolerability of galcanezumab in real life prognostic indicators persistent response.High-frequency episodic migraine (HFEM) chronic (CM) patients treated with who completed a observation were enrolled. The primary outcomes assessed during 12 months (V1-V12) change monthly days (MMDs) from baseline response rates ≥50% MMDs (MMD RR). secondary changes pain intensity (numerical rating scale [NRS]) acute medication intake (MAMI).We enrolled 191 (77.5%...
Chronic migraine (CM) is a highly disabling condition, affecting about 2% of the global population. Non-pharmacological treatments can be optimal for their non-invasive nature. This prospective, randomized, double-blind, controlled trial aimed to test efficacy therapeutic neuroscience education (TNE) in CM. Early response biomarkers were also evaluated. A total 80 CM patients consecutively enrolled and randomly allocated TNE or general program. Treatment effectiveness was evaluated at...