Thiago Henrique Lemes

ORCID: 0000-0002-7906-1337
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Nail Diseases and Treatments
  • Antifungal resistance and susceptibility
  • Fungal Infections and Studies
  • Plant Pathogens and Fungal Diseases
  • Fungal Biology and Applications
  • Essential Oils and Antimicrobial Activity
  • Mycotoxins in Agriculture and Food
  • Chemical synthesis and alkaloids
  • Tea Polyphenols and Effects
  • Graphene and Nanomaterials Applications
  • Synthesis and biological activity
  • Mosquito-borne diseases and control
  • Bone Tissue Engineering Materials
  • Pineapple and bromelain studies
  • Science and Education Research
  • biodegradable polymer synthesis and properties
  • Dental Implant Techniques and Outcomes
  • Natural product bioactivities and synthesis
  • Microbial Metabolism and Applications
  • Microbial infections and disease research
  • Phytochemical compounds biological activities
  • Curcumin's Biomedical Applications
  • Enzyme Production and Characterization
  • Nematode management and characterization studies
  • Entomopathogenic Microorganisms in Pest Control

Universidade Estadual Paulista (Unesp)
2019-2024

Faculdade de Medicina de São José do Rio Preto
2020

The impact of fungal diseases and the development antimicrobial agents against pathogenic fungi have emerged as a main global healthcare challenge. In this study, antifungal activity silver-loaded hydroxyapatite (Ag/HAP) nanocomposites (NCs) with different Ag content synthesized by one-pot microwave-assisted solvothermal method was evaluated sensitive resistant Candida species. NCs' composition morphology were characterized X-ray diffraction, field emission scanning electron microscopy,...

10.1021/acsanm.9b00091 article EN ACS Applied Nano Materials 2019-03-13

Abstract Dermatomycosis is an infection with global impacts caused especially by dermatophytes and Candida species. Current antifungal therapies involve drugs that face fungal resistance barriers. This clinical context emphasizes the need to discover new agents. Herein, potential of 10 curcumin analogs was evaluated against four dermatophyte The most active compound, 3,3’-dimethoxycurcumin, exhibited minimum inhibitory concentration values ranging from 1.9‒62.5 15.6‒62.5 µg ml−1 species,...

10.1093/lambio/ovae019 article EN Letters in Applied Microbiology 2024-03-01

Dermatomycoses are typical hair, skin, or nail infections caused mainly by dermatophytes and nondermatophytes: Trichophyton, Microsporum, Epidermophyton, Candida. In addition to the esthetical impact, pain, deformity, these mycoses can be a source of severe disease. The high cost treatment, toxicity, emergence resistant infectious agents justifies research into new drugs. This work evaluates fungicidal activity nanocomposites (NCs) based on reduced graphene oxide (rGO) loaded with silver...

10.1021/acsbiomaterials.3c00390 article EN ACS Biomaterials Science & Engineering 2023-11-09

Sporotrichosis is a subcutaneous mycosis that affects animals and humans. Varying in severity, occurrences range from local lesions to systemic involvement. It caused by thermodimorphic saprobic fungi the Sporothrix pathogenic clade. This study aimed identify species sexual idiomorph distribution patterns responsible for diagnosed cases of sporotrichosis São José do Rio Preto, Brazil. We included 188 isolates sp. feline 27 human origin, which underwent molecular identification genotyping...

10.1093/mmy/myac096 article EN Medical Mycology 2022-12-19

Onychomycoses are nail infections that require prolonged therapy and have high recurrence rates. Dermatophytes the main etiological agents of these infections, followed by yeasts non-dermatophyte filamentous fungi. The limited antifungal arsenal used to treat onychomycosis change in susceptibility profile contribute chronicity recalcitrant infections. present study aimed determine activity extracts obtained from pure mixed cultures Candida parapsilosis, Trichophyton mentagrophytes, rubrum....

10.3390/microbiolres15020057 article EN cc-by Microbiology Research 2024-05-22

Kombucha is obtained by fermentation of tea and sugar bacteria yeast. This beverage has several beneficial effects, including antimicrobial activity. The objective this study was to evaluate the antifungal activity extracts against dermatomycosis-causing fungi. Different types (black, white, green tea) times (10, 20, 30 days) were evaluated. Kombuchas filtered, liquid-liquid extraction with ethyl acetate. Minimum inhibitory concentrations (MIC) determined clinical isolates dermatophytes...

10.55251/jmbfs.5899 article EN Journal of Microbiology Biotechnology and Food Sciences 2024-06-10

Onychomycoses are nail infections caused primarily by dermatophytes fungi, yeasts, and other filamentous characterized persistent infections, prolonged therapy, high recurrence rates. In clinical practice, some of these occurrences present two or more microorganisms, the interactions among them can change chemical environment mediated small diffusible molecules, producing a competitive niche. The aim this study was to evaluate antifungal activity individual extracts pure cultures Candida...

10.52600/2763-583x.bjcr.2021.1.4.135-152 article EN cc-by Brazilian Journal of Case Reports 2021-11-15

Fungal infections caused by Candida species has increased significantly in recent years. Additionally, resistance to conventional therapy is an aggravating factor causing high morbidity and mortality, especially immunocompromised patients or those undergoing treatment with another antimicrobials. During the infection process, produces metabolites which can self-regulate population density, addition controlling several virulence factors exerting action on other microorganisms. In view of this...

10.52600/2763-583x.bjcr.2023.3.1.24-29 article EN cc-by Brazilian Journal of Case Reports 2022-11-29

 The physical chemical interactions present in mixed microbiota niches induce changes the physiology of microorganisms, thereby affecting cellular viability; mechanism these should be explored, and vitro screening new antifungal molecules is essential for success therapeutic approaches.

10.26226/morressier.5ac39994d462b8028d899ea2 article EN 2018-04-16

Las onicomicosis, también conocidas popularmente como micosis ungueales, son infecciones fúngicas que afectan el lecho ungueal y tejidos adyacentes con hiperqueratosis, decoloración onicólisis, causadas por hongos dermatofitos, levaduras filamentosos no dermatofitos.Entre los destacan agente etiológico de esta micosis, del género Microsporum, Epidermophyton Trichophyton la levadura Candida albicans.La interacción entre diferentes ha sido objeto varios estudios, en ya se demostrado...

10.31692/iicointerpdvs.0071 article ES SOCIEDADE 5.0:EDUCAÇÃO,CIÊNCIA,TECNOLOGIA E AMOR 2020-01-01

Onicomicoses, também conhecidas popularmente como micoses em unhas, são infecções fúngicas que afetam o leito ungueal e tecidos adjacentes com hiperqueratose, descoloração onicólise, causadas por fungos dermatófitos, leveduras filamentosos não dermatófitos. Dentre esses se destacam agente etiológico desta micose, os do gênero Microsporum, Epidermophyton Trichophyton a levedura Candida albicans. A interação entre diferentes tem sido objeto de diversos estudos, na qual já foi demonstrado...

10.31692/2764-3433.v1i1.63 article PT International Journal of Health Science 2021-12-15
Coming Soon ...