A5089346982- Global Maternal and Child Health
- Cervical Cancer and HPV Research
- Adolescent Sexual and Reproductive Health
- Reproductive Health and Contraception
- Global Cancer Incidence and Screening
- Intimate Partner and Family Violence
- Health disparities and outcomes
- Epilepsy research and treatment
- Parasitic Diseases Research and Treatment
- Gestational Diabetes Research and Management
- Vaccine Coverage and Hesitancy
- Poverty, Education, and Child Welfare
- Migration, Health and Trauma
- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- COVID-19 Impact on Reproduction
- HIV/AIDS Research and Interventions
- Hospital Admissions and Outcomes
- HIV, Drug Use, Sexual Risk
- Healthcare Operations and Scheduling Optimization
- Sex work and related issues
- Resilience and Mental Health
- Public Health Policies and Education
- Ethics in Clinical Research
Medical College of Wisconsin
2018-2025
Makerere University
2015-2024
International Institute of Tropical Agriculture
2019-2024
Maseno University
2022-2024
National Institutes of Health
2022
University of Oxford
2022
University of California, Los Angeles
2022
Kyambogo University
2022
Elcotherm (Switzerland)
2017
Jimma University
2016
Uganda has one of the highest total fertility rates globally and in Sub-Saharan Africa. Her high is mainly attributed to unmet need for family planning. Use Long-acting reversible contraceptives (LARC) low (13%) yet they are most cost-effective contraceptives. This study aimed assess reproductive aged women's knowledge, attitudes, factors associated with use LARC.A cross-sectional was conducted involving 565 women (15-49 years) attending private public health facilities Lubaga division,...
BackgroundNodding syndrome is a poorly understood neurological disorder that predominantly occurs in Africa. We hypothesised nodding neuroinflammatory disorder, induced by antibodies to Onchocerca volvulus or its Wolbachia symbiont, cross-reacting with host neuronal proteins (HNPs), and doxycycline can be used as treatment.MethodsIn this randomised, double-blind, placebo-controlled, phase 2 trial, we recruited participants from districts affected northern Uganda. included children...
Abstract Introduction Cervical cancer continues to pose a major public health challenge in low-income countries. screening programs enable early detection and effectively reduce the incidence of cervical as well late-stage diagnosis mortality. However, uptake remains suboptimal Uganda. This study assessed correlates intention screen for among women Kyotera district Central Methods We analyzed cross-sectional data collected determine effectiveness community audio towers (CATs) modality...
Timely emergency medical services (EMS) are particularly important among trauma patients, as inefficient EMS systems can result in potentially avoidable death before reaching a hospital. The Dhulikhel Hospital Dispatch Center coordinates and monitors growing network of ambulances, including seven Type B ambulances staffed with trained prehospital care provider equipment. This study evaluates the outcomes patients transported by to Hospital's Emergency Department, monitored Center. Data were...
During adolescence, a critical developmental phase, cognitive, psychological, and social states interact with the environment to influence behaviors like decision-making interactions. Depressive symptoms are more prevalent in adolescents than other age groups which may affect socio-emotional behavioral development including academic achievement. Here, we determined association between depression symptom severity impairment among enrolled secondary schools of Eastern Central Uganda. This...
This cross-sectional study evaluates whether the use of a speech recognition tool is associated with documentation efficiency among clinicians at rural US health care system.
Uganda like many developing countries still experiences high levels of maternal and perinatal deaths despite a decade death review (MPDR) program. Oyam district has been implementing MPDR since 2008 with varying successes among the health facilities. This paper presents factors that influence conduct reviews in District, Uganda.This was cross-sectional study where both qualitative quantitative data were collected. Semi-structured interviews administered to 66 workers ten key informants (KIs)...
This study aimed to describe the intentions of and barriers use long-acting reversible contraceptives (LARCs) in post-abortion period among women seeking abortion mainland China.A cross-sectional was conducted from July 2015 December using a waiting room questionnaire. A total 381 abortions were recruited at public hospital clinic. The outcome variable an 'intention-to-use' LARCs immediate period. Chi-square tests used assess associations between categorical variables. Statistically...
The use of implants and Intra-uterine devices (IUD) during the post-partum period is very low in Uganda especially rural settings. Long-acting reversible contraceptives (LARC) are known to be most cost-effective for prevention unintended pregnancy unsafe abortions. This study aimed at determining factors associated with long-acting contraceptive among women extended postpartum Uganda.We conducted a household-based, cross-sectional 400 two communities Mityana district, central Uganda....
Uganda clinical guidelines recommend routine screening of pregnant women for intimate partner violence (IPV) during antenatal care (ANC). Healthcare providers play a critical role in identifying IPV pregnancy ANC clinics. This study explored facilitators and barriers (perinatal screening) by ANC-based healthcare workers Uganda.We conducted qualitative in-depth interviews among twenty-eight purposively selected one rural an urban-based health center Eastern Central respectively. Barriers to...
Introduction: high Tuberculosis treatment default rate (17%) and sub-optimal completion rates (45%) has burdened Kampala. Nevertheless, there are observable increase in the number of patients on TB DOT; from 6% to 29% two consecutive annual reports. The main objective was determine association patient attitudes towards community-based observers drug adherence directly observed for
Firearm fatalities are a major public health concern, claiming the lives of 40,000 Americans each year. While firearm have pervasive effects, it is unclear how social determinants (SDOH) such as residential racial segregation, income inequality, and community resilience impact fatalities. This study investigates relationships between these SDOH likelihood fatalities.County-level data from Agency for Health Care Research Quality 2019 were analyzed, covering 72 Wisconsin counties. The...
Sexual coercion is associated with sexually transmitted infections and unwanted pregnancies consequential unsafe abortions increased maternal morbidity mortality. Current literature focuses mainly on its risk factors but less resultant deleterious health effects. We conducted a study to determine the prevalence of sexual association among young pregnant women. In cross-sectional study, four hundred sixteen (416) consenting females aged 15–24 years attending antenatal clinics in Lubaga...
The global burden of cervical cancer is concentrated in low-and middle-income countries (LMICs), with the greatest Africa. Targeting limited resources to populations need maximize impact essential. objectives this study were geocode data from a population-based registry Kampala, Uganda, create high-resolution disease maps for prevention and control planning, share lessons learned optimize efforts other low-resource settings.Kampala Cancer Registry records diagnoses between 2008 2015 updated...
A large amount of preparation goes into setting up trials. Different challenges and lessons are experienced. Our trial, testing a treatment for nodding syndrome, an acquired neurological disorder unknown cause affecting thousands children in Eastern Africa, provides unique case study. As part study to determine the aetiology, understand pathogenesis develop specific treatment, we set clinical trial remote district hospital Uganda. This paper describes our experiences documents supportive...
Nodding syndrome is a poorly understood neurological disorder of unknown aetiology, affecting several thousand children in Africa. There has been consistent epidemiological association with infection by the filarial parasite, Onchocerca volvulus and antibodies to leiomodin DJ-1, cross-reacting O.volvulus proteins, have reported. We hypothesized that nodding neuro-inflammatory disorder, induced or its symbiont, Wolbachia, human neuron proteins doxycycline, which kills through effects on may...
Epidemiological studies suggest a link between onchocerciasis and various forms of epilepsy, including nodding syndrome (NS). The aetiopathology associated epilepsy remains unknown. This case-control study investigated potential risk factors that may lead to NS other non-nodding (OFE) in northern Uganda. We consecutively recruited 154 persons with (aged 8 20 years), age-frequency matched them OFE healthy community controls. Participants’ socio-demography, medical, family, migration histories...
Abstract Objective Nodding syndrome is a poorly understood epileptic encephalopathy characterized by unique seizure type—head nodding—and associated with Onchocerca volvulus infection. We hypothesized that altered immune activation in the cerebrospinal fluid (CSF) and plasma of children nodding may yield insights into pathophysiology progression this disorder. Method conducted case‐control study 154 (8 years or older) long‐standing healthy age‐matched community controls 3 districts northern...
Cases of coronavirus disease 2019 (COVID-19) detected, and COVID-19 associated mortality increased since the first case was confirmed in Uganda. While adherence to WHO-recommended measures disrupt transmission has been implemented, it reported be sub-optimal. An increase intimate partner violence (IPV) cases linked enforcement lockdowns other preventive especially informal settings Kampala. We determined association between among women dwelling Kampala, Between July October 2020, we...
Abstract Background Adolescence is a critical development transition period that increases vulnerability to poor mental health outcomes. Recent evidence suggests 9.6% and 11.5% of adolescents in Uganda experienced behavioral emotional disorders, respectively. We examined the factors associated with outcomes among school-going Uganda. Methods This cross-sectional study surveyed 1,953 students aged 10-24 enrolled Central Eastern secondary schools selected by stratified random sampling. Our...
Objective Plasmodium falciparum is epileptogenic and in malaria endemic areas, a leading cause of acute seizures. In these asymptomatic infections are common but considered benign so, not treated. The effects such on seizures patients with epilepsy unknown. This study examined the relationship between P. infection seizure control children unique type, nodding syndrome. Design cross-sectional was nested an ongoing trial ‘Doxycycline for treatment syndrome ( NCT02850913 )’. We hypothesised...