A5026295604- Burn Injury Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Nosocomial Infections in ICU
- Wound Healing and Treatments
- Thyroid and Parathyroid Surgery
- Esophageal and GI Pathology
- Injury Epidemiology and Prevention
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- Cancer Risks and Factors
- Gut microbiota and health
- Estrogen and related hormone effects
- Eosinophilic Esophagitis
- Airway Management and Intubation Techniques
- Cancer, Lipids, and Metabolism
- Disaster Response and Management
- Voice and Speech Disorders
- Inflammatory mediators and NSAID effects
- Cholangiocarcinoma and Gallbladder Cancer Studies
- HIV Research and Treatment
- Menopause: Health Impacts and Treatments
- Pancreatic and Hepatic Oncology Research
Karolinska Institutet
2016-2025
University of Antwerp
2021-2025
Ghent University
2010-2025
Ghent University Hospital
2011-2024
Science for Life Laboratory
2016-2023
Karolinska University Hospital
2016-2023
Svenska Örtmedicinska Institute
2019
WinnMed
2019
RELX Group (United States)
2017
Philadelphia University
2017
Rationale: The clinical relevance of Aspergillus-positive endotracheal aspirates in critically ill patients is difficult to assess.Objectives: We externally validate a algorithm discriminate Aspergillus colonization from putative invasive pulmonary aspergillosis this patient group.Methods: performed multicenter (n = 30) observational study including with one or more aspirate cultures 524). diagnostic accuracy was evaluated using 115 histopathologic data, considered the gold standard....
Mainly due to its extremely vulnerable population of critically ill patients, and the high use (invasive) procedures, intensive care unit (ICU) is epicenter infections. These infections are associated with an important rise in morbidity, mortality, healthcare costs. The additional problem multidrug-resistant pathogens boosts adverse impact ICUs. Several factors influence rapid spread ICU, e.g., new mutations, selection resistant strains, suboptimal infection control. Among gram-positive...
Summary Background: Comorbidities may have an important impact on survival, and comorbidity scores are often implemented in studies assessing prognosis. The Charlson Comorbidity index is most widely used, yet several adaptations been published, all using slightly different conversions of the International Classification Diseases (ICD) coding. Objective: To evaluate which coding should be used to assess quantify for Index registry-based research, particular if older ICD versions will used....
Proton pump inhibitors (PPIs) are among the most commonly prescribed drugs. Concerns have been raised about a potentially increased risk of gastric cancer following long-term use. Our aim is to assess associated with PPI use, taking into account underlying indications.This population-based cohort study. Standardised incidence ratios (SIRs) and 95% CIs were calculated compare users corresponding background population, while confounding by indication account.Population-based study in Sweden...
Objective Gastric infection with Helicobacter pylori is a strong risk factor for non-cardia gastric adenocarcinoma. The aim of this study was to assess whether the adenocarcinoma and decreases after eradication treatment H. in Western population. Design This nationwide, population-based cohort Sweden 2005–2012. Data from Swedish Prescribed Drug Registry provided information on treatment, whereas concerning newly developed retrieved Cancer Registry. individuals who had received compared...
Objectives To assess the recent prognostic trends in oesophageal adenocarcinoma and squamous cell carcinoma undergoing resectional surgery no such surgery. Additionally, risk factors for death were assessed each of these patient groups. Design Cohort study. Setting A population-based, nationwide study Sweden. Participants All patients diagnosed with Sweden from 1 January 1990 to 31 December 2013, follow-up until 14 May 2017. Outcome measures Observed relative (to background population)...
Abstract Sweden was well equipped to prevent the pandemic of COVID-19 from becoming serious. Over 280 years collaboration between political bodies, authorities, and scientific community had yielded many successes in preventive medicine. Sweden’s population is literate has a high level trust authorities those power. During 2020, however, ten times higher death rates compared with neighbouring Norway. In this report, we try understand why, using narrative approach evaluate Swedish policy role...
Abstract A high-fat diet can lead to gut microbiota dysbiosis, chronic intestinal inflammation, and metabolic syndrome. Notably, resulting phenotypes, such as glucose insulin levels, colonic crypt cell proliferation, macrophage infiltration, exhibit sex differences, females are less affected. This is, in part, attributed hormones. To investigate if there differences the estrogenic ligands attenuate diet-induced we used whole-genome shotgun sequencing characterize impact of diet, sex, on...
Antibiotics represent the most common type of medication used during pregnancy and infancy. have been proposed as a possible factor in changes microbiota composition, which may play role aetiology autism attention deficit/hyperactivity disorder (ADHD). Our aim was to investigate association between maternal early-life antibiotic use ADHD childhood. This Swedish nation-wide population-based cohort study included all first live singleton births (N = 483,459) January 2006 December 2016. The...
The transgenerational maternal effects of polycystic ovary syndrome (PCOS) in female progeny are being revealed. As there is evidence that a male equivalent PCOS may exists, we ask whether sons born to mothers with (PCOS-sons) transmit reproductive and metabolic phenotypes their progeny. Here, register-based cohort clinical case-control study, find PCOS-sons more often obese dyslipidemic. Our prenatal androgenized PCOS-like mouse model or without diet-induced obesity confirmed dysfunctions...