A5030694789- Dysphagia Assessment and Management
- Diabetes Treatment and Management
- Gastroesophageal reflux and treatments
- Pharmaceutical studies and practices
- thermodynamics and calorimetric analyses
- Esophageal and GI Pathology
- Chronic Disease Management Strategies
- Nanoparticle-Based Drug Delivery
- Pharmaceutical Practices and Patient Outcomes
- Field-Flow Fractionation Techniques
Roche (Switzerland)
2023-2024
Universität Greifswald
2023-2024
Older adults represent the major target population for oral medications, due to high prevalence of multimorbidity. To allow successful pharmacological treatments, patients need adhere their medication and, thus, patient-centric drug products with a level acceptability by end users are needed. However, knowledge on appropriate size and shape solid dosage forms, as most commonly used forms in older adults, is still scarce. A randomized intervention study was performed including 52 (65 94...
Swallowability, visual perception, and any handling to be conducted prior use are all influence factors on the acceptability of an oral dosage form by patient. Knowing preferences older adults, as major group medication end users, is needed for patient-centric drug development. This study aimed at evaluating ability adults handle tablets well assess anticipated swallowability tablets, capsules, mini based perception. The randomized intervention included 52 (65 94 years) younger (19 36...
Acceptable swallowability and complete esophageal transit are decisive for the safe effective administration of solid oral dosage forms. This applies in particular to main user group medicines, older adults, who often suffer from swallowing difficulties. It is well known that surface properties play an important role this respect. In past, has led development numerous coating formulations tablets with improved swallowability. However, vitro especially vivo data investigating a positive...