Wei Zhu

ORCID: 0000-0002-7957-7843
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Tea Polyphenols and Effects
  • Antioxidant Activity and Oxidative Stress
  • Adipokines, Inflammation, and Metabolic Diseases
  • Adipose Tissue and Metabolism
  • Genomics, phytochemicals, and oxidative stress
  • Biochemical Analysis and Sensing Techniques
  • Bioactive Compounds and Antitumor Agents
  • Cholesterol and Lipid Metabolism
  • Carbon Nanotubes in Composites
  • Diamond and Carbon-based Materials Research
  • Lipid Membrane Structure and Behavior
  • Semiconductor materials and devices
  • Essential Oils and Antimicrobial Activity
  • Advanced Glycation End Products research
  • Physical Activity and Health
  • Quantum Dots Synthesis And Properties
  • Peroxisome Proliferator-Activated Receptors
  • Pharmacological Effects of Natural Compounds
  • Postharvest Quality and Shelf Life Management
  • Lipid metabolism and biosynthesis
  • Cardiovascular and exercise physiology
  • Proteins in Food Systems
  • Polysaccharides and Plant Cell Walls
  • SARS-CoV-2 and COVID-19 Research

University of California, Davis
2020-2024

Shanghai Pudong New Area Gongli Hospital
2024

Second Military Medical University
2018-2024

Zhejiang Provincial People's Hospital
2019-2024

Bristol-Myers Squibb (United States)
2024

Hangzhou Medical College
2019-2024

Zhengzhou University
2023-2024

Second Affiliated Hospital of Zhejiang University
2024

Tianjin University of Commerce
2023

Huazhong Agricultural University
2014-2022

Abstract Background Recent evidence suggests that higher calcium and/or vitamin D intake may be associated with lower body weight and better metabolic health. Due to contradictory findings from intervention trials, we investigated the effect of plus 3 (calcium+D) supplementation on anthropometric profiles during energy restriction in healthy, overweight obese adults very-low consumption. Methods Fifty-three subjects were randomly assigned an open-label, randomized controlled trial receive...

10.1186/1475-2891-12-8 article EN cc-by Nutrition Journal 2013-01-08

Coronavirus epidemic 2019 (COVID-19), instigated by SARS-CoV-2 virus, is recently raising worldwide and inspiring global health worries. The main 3-chymotrypsin-like cysteine protease (3CL

10.1111/jfbc.13432 article EN Journal of Food Biochemistry 2020-08-11

The filamentous fungi XLA and XLC isolated from Cd-contaminated soil were identified morphologically phylogenetically as Paecilomyces lilacinus Mucoromycote sp., respectively. minimum inhibitory concentrations (MICs) of Cd2+, Co2+, Cu2+, Zn2+, Cr3+ Cr6+ in mineral (MM) medium agar plates 29,786, 2945, 9425, 5080, 1785 204 mg·L−1 for 11,240, 884, 9100, 2540, 3060 51 XLC, Favorable biosorption conditions adsorption Cd2+ by the tested investigated. Efficient performances biosorbents described...

10.3390/ijms160715670 article EN International Journal of Molecular Sciences 2015-07-10

Microbial bioremediation is a promising technology to treat heavy metal-contaminated soils. However, the efficiency of filamentous fungi as agents remains unknown, and detoxification mechanism metals by unclear. Therefore, in this study, we investigated cell morphology antioxidant systems Penicillium chrysogenum XJ-1 response different Cd concentrations (0–10 mM) using physico-chemical biochemical methods. was mainly bound wall. The malondialdehyde (MDA) level cells increased 14.82–94.67...

10.3389/fmicb.2015.01422 article EN cc-by Frontiers in Microbiology 2015-12-21

Pancreatic lipase (PL) is a critical enzyme associated with hyperlipidemia and obesity. A previous study of ours suggested that persimmon tannin (PT) was the main component accounting for antihyperlipidemic effects fruits, but underlying mechanisms were unclear. In this present study, inhibitory effect PT on PL studied possible evaluated by fluorescence spectroscopy, circular dichroism (CD) spectra, isothermal titration calorimetry (ITC), molecular docking. had high affinity to inhibited...

10.1021/acs.jafc.8b00850 article EN Journal of Agricultural and Food Chemistry 2018-05-28

Diet is of major importance in modulating intestinal inflammation, as the gastrointestinal tract directly exposed to high concentrations dietary components. Procyanidins are flavan-3-ol oligomers abundant fruits and vegetables. Although with limited or no absorption, they can have GI health benefits which promote overall health. We previously observed that epicatechin gallate (ECG) epigallocatechin (EGCG) dimers inhibit vitro colorectal cancer cell proliferation invasiveness....

10.1016/j.redox.2024.103275 article EN cc-by-nc-nd Redox Biology 2024-07-20

Water-treated maize stems were subjected to delignification with peroxymonosulfuric acid at 20 °C for 144 h, peroxyformic 80 6 peracetic 50 and 2% hydrogen peroxide 45 12 h pH 1.5, 4.4, 9.5, 11.5, 12.0, 12.6, respectively, which solubilized 47.1, 91.3, 33.3, 16.6, 15.9, 17.4, 86.2, 87.7, 91.3% of the original lignin, respectively. Substantial lignins released during treatment ≥11.5, whereas an insignificant effect on was observed by using acid, under acidic, natural, weakly alkaline media...

10.1021/jf990646e article EN Journal of Agricultural and Food Chemistry 2000-03-04

It has been proposed that the gut microbiome may be related to obesity, and diet-induced obesity alter microbiota composition while persimmon tannin can improve it.

10.1039/c7fo00995j article EN Food & Function 2017-11-28

Abstract This study aimed to investigate the association between Serum Uric Acid (UA) Creatinine (Cr) Ratio (UA/Cr) and metabolic syndrome (MetS) in postmenopausal women. A total of 455 patients with MetS 457 age- gender- matched controls were included present retrospective study. levels cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL-C), low-density (LDL-C), fasting plasma glucose (FPG), Cr, UA measured. We employed logistic regression analysis serum UA/Cr significantly...

10.1097/md.0000000000019959 article EN cc-by-nc Medicine 2020-04-01

Colorectal cancer (CRC) is prevalent worldwide. Dietary consumption of procyanidins has been linked to a reduced risk developing CRC. The epidermal growth factor (EGF) receptor (EGFR) signaling pathway frequently dysregulated in Our earlier research showed that the procyanidin dimers epicatechin gallate (ECG) and epigallocatechin (EGCG), through their interaction with lipid rafts, inhibit EGFR decrease CRC cell growth. process invasion metastasis involves matrix metalloproteinases (MMPs),...

10.1016/j.redox.2023.102827 article EN cc-by Redox Biology 2023-07-25

Coronavirus disease 2019 (COVID-19) was recently raised and starting from China to all over the world. The viral main protease (3-chymotrypsin-like cysteine enzyme) controls COVID-19 duplication manages its life cycle, making it a drug discovery target. Therefore, herein, we analyzed theoretical approaches of 10 structurally different hydrolysable tannins as natural anti-COVID-19 through binding with 2019-nCoV using molecular docking modelling via Molecular Operating Environment (MOE v2009)...

10.20944/preprints202003.0277.v1 preprint EN 2020-03-17
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