- Nanocluster Synthesis and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
Yonsei University
2018-2024
DNA secondary structures, such as dimers and hairpins, are important for the synthesis of template-embedded silver nanoclusters (DNA/AgNCs). However, arrangement AgNCs within a given template how AgNC influences structure still unclear. Here, we introduce noncanonical head-to-head hairpin nanostructure that is driven by orange-emissive AgNCs. Through detailed in-gel analysis, sugar backbone switching, inductively coupled plasma mass spectrometry, small-angle X-ray scattering, small angle...
Greater understanding of the mutual influence between DNA and associated nanomaterial on properties each other can provide alternative strategies for designing developing nanomachines. secondary structures are essential encapsulating highly emissive silver nanoclusters (DNA/AgNCs). Likewise, AgNCs stabilize structures, such as hairpin DNA, duplex parallel-motif triplex. In this study, we found that fluorescence encapsulated within a Hoogsteen triplex structure be turned off in response to pH...
Abstract MicroRNAs (miRNAs) are small RNA molecules, typically 21‒22 nucleotides in size, which play a crucial role regulating gene expression most eukaryotes. Their significance various biological processes and disease pathogenesis has led to considerable interest their potential as biomarkers for diagnosis therapeutic applications. In this study, novel method sensing target miRNAs using Tailed‐Hoogsteen triplex DNA‐encapsulated Silver Nanoclusters (DNA/AgNCs) is introduced. Upon...
The redox regulation, maintaining a balance between oxidation and reduction in living cells, is vital for cellular homeostasis, intricate signaling networks, appropriate responses to physiological environmental cues. Here, novel sensor, based on DNA-encapsulated silver nanoclusters (DNA/AgNCs) well-defined chemical fluorophores, effectively illustrating states live cells introduced. Among various i-motif DNAs, the photophysical property of poly-cytosines (C
The structural shift of a DNA hairpin-dimer is as important the sequence in determining fluorescent properties DNA-stabilized silver nanoclusters (DNA/AgNCs).
DNA-encapsulated Silver Nanoclusters (DNA/AgNCs) based sensors have gained increasing attention in past years due to their diverse applications bioimaging, biosensing, and enzymatic assays. Given the potential of DNA/AgNCs for practical applications, systematic studies fluorescent stability over an extended period is necessary. However, correlation between nucleic acid properties long-term less known. With locking-to-unlocking sensors, which secondary structure DNA template standardized, we...