A5054773406- Acute Kidney Injury Research
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Parathyroid Disorders and Treatments
- Blood Pressure and Hypertension Studies
- Diagnosis and Treatment of Venous Diseases
- Diabetes Treatment and Management
- Erythropoietin and Anemia Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Renal and Vascular Pathologies
- Protease and Inhibitor Mechanisms
- Central Venous Catheters and Hemodialysis
- Muscle and Compartmental Disorders
- Peripheral Artery Disease Management
- Hormonal Regulation and Hypertension
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Renal Diseases and Glomerulopathies
- Iron Metabolism and Disorders
- Ion Transport and Channel Regulation
- Aortic aneurysm repair treatments
- Cardiovascular Health and Disease Prevention
- Liver Disease Diagnosis and Treatment
- Heart Failure Treatment and Management
Magna Graecia University
2016-2025
Dulbecco Telethon Institute
2024
University of Ioannina
2024
Multidisciplinary Digital Publishing Institute (Switzerland)
2020
Department of Medical Sciences
2016-2017
Azienda Ospedaliero Universitario Mater Domini
2016
University of Palermo
2015
National Research Council
2015
Jeonbuk National University
2013
Universitätsklinikum Würzburg
2013
Significance Statement In this randomized crossover clinical trial in patients with CKD and without type 2 diabetes, we assessed the albuminuria-lowering effect of sodium glucose co-transporter (SGLT2) inhibitor dapagliflozin mineralocorticoid receptor antagonist (MRA) eplerenone individually combination. We demonstrated that effects alone are additive when they used combination, resulting a clinically relevant albuminuria reduction 53% after 4 weeks dapagliflozin-eplerenone treatment. The...
β-Catenin is a transcriptional activator that regulates embryonic development as part of the Wnt pathway and also plays role in tumorigenesis. The mechanisms leading to Wnt-induced stabilization β-catenin, which results its translocation nucleus activation transcription, have been an area intense interest. However, it not clear whether stimuli other than Wnts can lead important β-catenin and, if so, what factors mediate biologic processes might be regulated. Herein we report stabilized...
Iron deficiency is a common cause of anaemia in non-dialysis chronic kidney disease (ND-CKD). Controversies exist about the optimal route administration for iron therapy. Liposomal iron, new generation oral with high gastrointestinal absorption and bioavailability low incidence side effects, seems to be promising strategy replacement. Therefore, we conducted study determine whether liposomal compared intravenous (IV) improves ND-CKD patients. In this randomized, open-label trial, 99 patients...
We tested for the presence of coronary calcifications in patients with chronic renal disease not on dialysis and studied its progression 181 consecutive non-dialyzed who were followed a median 745 days. Coronary (calcium score) tallied Agatston units by computed tomography, stratified into two groups their baseline calcium score (100 U or less over 100 U). Survival was measured progression. Cardiac death myocardial infarction occurred 29 significantly more frequent those scores (hazard ratio...
Glycogen synthase kinase (GSK) 3beta is a negative regulator of stress-induced cardiomyocyte hypertrophy. It not clear, however, if GSK-3beta plays any role in regulating normal cardiac growth and function. Herein we report that transgenic mouse expressing wild type the heart has dramatic impairment post-natal as well markedly abnormal contractile The most striking phenotype, grossly impaired diastolic relaxation, which leads to increased filling pressures left ventricle massive atrial...
Rational: Our aim was to investigate the quality of life (QoL) in 103 patients undergoing chronic hemodialysis (HD) an integrated assessment clinical, personological, and adaptation parameters, also a non-urban context.Objectives: We collected data from all HD attending four units. Clinical status assessed by Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines Age-adjusted Charlson Comorbidity Index (ACCI). Patients completed following questionnaires: Life Short Form (KDQOL-SF),...