A5101425946- Liver Disease Diagnosis and Treatment
- Bone Tissue Engineering Materials
- MicroRNA in disease regulation
- Fibroblast Growth Factor Research
- Structural Behavior of Reinforced Concrete
- ZnO doping and properties
- Pancreatitis Pathology and Treatment
- Nerve injury and regeneration
- Electrospun Nanofibers in Biomedical Applications
- Cancer-related Molecular Pathways
- Structural Engineering and Vibration Analysis
- Thermodynamic and Structural Properties of Metals and Alloys
- Bone Metabolism and Diseases
- Kruppel-like factors research
- Connective tissue disorders research
- Peroxisome Proliferator-Activated Receptors
- Cancer-related molecular mechanisms research
- Dental Implant Techniques and Outcomes
- Neuroscience of respiration and sleep
- Graphene and Nanomaterials Applications
- Electronic Packaging and Soldering Technologies
- Structural Load-Bearing Analysis
- Liver Diseases and Immunity
- DNA Repair Mechanisms
- Orthopaedic implants and arthroplasty
Wenzhou Medical University
2021-2024
Second Affiliated Hospital of Soochow University
2022-2024
Soochow University
2022-2024
First Affiliated Hospital of Jiangxi Medical College
2023
Jiangxi Provincial People's Hospital
2023
Yueqing People's Hospital
2022
China General Nuclear Power Corporation (China)
2021
Shanghai Jiao Tong University
2018
Taiyuan University of Technology
2017
Abstract Non‐alcoholic fatty liver disease (NAFLD) is a progressive that can further evolve towards fibrosis and hepatocellular carcinoma in the end stage. Costunolide (Cos) natural sesquiterpene lactone exhibits both anti‐inflammatory antioxidant properties. However, therapeutic effect of Cos on NAFLD not clear. In this study, we explored potential protective mechanism NAFLD. C57BL/6 mice were fed with high‐fat diet (HFD) to induce was administered by gavage observe We demonstrated oral...
Guided bone regeneration (GBR) technology has been widely used for the of periodontal defects. However, limited mechanical properties and potential currently available GBR membranes often limit their repair effectiveness. In this paper, serum-derived growth factor lysophosphatidic acid (LPA) nanoparticles dopamine-decorative nanohydroxyapatite (pDA/nHA) particles were double-loaded into polylactic-glycolic acid/polycaprolactone (PLGA/PCL) scaffolds as an organic/inorganic biphase delivery...
It remains a major challenge to simultaneously achieve bone regeneration and prevent infection in the complex microenvironment of repairing defects. Here, we developed novel ECM-mimicking scaffold by coaxial electrospinning be endowed with multibiological functions. Lysophosphatidic acid (LPA) zinc oxide (ZnO) nanoparticles were loaded into poly-lactic-co-glycolic acid/polycaprolactone (PLGA/PCL, PP) sheath layer nanofibers, deferoxamine (DFO) its core layer. The PP-LPA-ZnO/DFO maintained...
Ionic substitution can effectively activate the surface of hydroxyapatite (HA) for bone repair and regeneration processes. Therefore in this study, magnesium (Mg)-, zinc (Zn)-, Mg/Zn-codoped HA was prepared by a hydrothermal method. The results experimental first-principles calculations verify existence Mg Zn ions structure altering cell parameters, crystallinity, particle size. also showed that are actively accommodated at Ca(1) Ca(2) positions, which not only inhibit formation but promote...
Accumulating articles have reported the pivotal regulatory roles of circular RNAs (circRNAs) in non-small-cell lung cancer (NSCLC) tumorigenesis. Here, our purpose was to explore role circ_0002346 NSCLC progression and its associated mechanism.Cell proliferation ability assessed by a 5-ethynyl-2'-deoxyuridine (EDU) assay colony formation assay. Transwell assays were conducted analyze cell migration invasion abilities. Cell apoptosis analyzed flow cytometry using caspase3 activity kit. The...
Introduction: Mantle cell lymphoma (MCL) can be stratified into blastoid and classical subtypes based on morphological features, with the former subtype having a poorer prognosis. Despite recent advances in targeted approaches, including multiple bruton tyrosine kinase inhibitors which yield impressive clinical responses improve prognoses, MCL remains an incurable disease frequent relapses. Additional therapeutic interventions are therefore unmet medical needs for management of patients MCL....
Fibroblast growth factor 21 (FGF21) is an important metabolic regulator that has multiple beneficial effects on glucose homeostasis and lipid metabolism. Although circulating levels of FGF21 are mainly derived from liver, also found in other tissues fluids including the cerebrospinal fluid (CSF). The aim present study was to investigate relationships CSF and/or plasma with parameters a normal-weight Chinese population.Forty-five subjects (22 males 23 females) were recruited patient...