Matthew Sinclair

ORCID: 0000-0002-8003-9786
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About
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Research Areas
  • Antimicrobial Resistance in Staphylococcus
  • Dialysis and Renal Disease Management
  • Infective Endocarditis Diagnosis and Management
  • Transplantation: Methods and Outcomes
  • Renal Diseases and Glomerulopathies
  • Bacterial Identification and Susceptibility Testing
  • Homelessness and Social Issues
  • HIV/AIDS drug development and treatment
  • Urinary Tract Infections Management
  • Diversity and Career in Medicine
  • Ion Transport and Channel Regulation
  • COVID-19 and healthcare impacts
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Diabetes Treatment and Management
  • Clostridium difficile and Clostridium perfringens research
  • Renin-Angiotensin System Studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Medical Education and Admissions
  • Mechanical Circulatory Support Devices
  • Burkholderia infections and melioidosis
  • Healthcare professionals’ stress and burnout
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Automotive and Human Injury Biomechanics
  • Mycobacterium research and diagnosis

Duke University
2019-2024

Clinical Research Institute
2020-2024

Duke University Hospital
2020-2021

Duke Medical Center
2021

Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2019

The University of Western Australia
2016

Introduction: End stage kidney disease (ESKD) affects an estimated 5500 persons living in the United States without legal residency documentation. One likely, but underappreciated cause of ESKD Hispanic migrant population, is chronic unknown etiology (CKDu). CKDu interstitial nephritis that disproportionately young adult agricultural workers Central America who lack traditional risk factors for disease. In underserved populations, such as those at CKDu, substantial barriers to optimal care...

10.1101/2025.02.28.25323090 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2025-03-04

We undertook a prospective, matched cohort study of patients with Staphylococcus aureus bacteremia (SAB) and gram-negative (GNB) to compare the characteristics, outcomes, chemokine cytokine response in transplant recipients immunocompetent, nontransplant recipients. Fifty-five (GNB n = 29; SAB 26) 225 114; 111) were included for clinical analysis. Transplant GNB had significantly lower incidence septic shock than (10.3% vs 30.7%, p .03). Thirty-day mortality did not differ between 15.8%,...

10.1111/ajt.16388 article EN cc-by-nc-nd American Journal of Transplantation 2020-11-01

Introduction Coronavirus disease 2019 (COVID-19) has profoundly affected outpatient dialysis. In the United States, patients requiring maintenance dialysis share many risk factors associated with poor outcomes from COVID-19: lower socioeconomic status, older age, hypertension, and diabetes mellitus.1 Many dialysis-dependent have reduced immune responses, 85% of treating by in-center hemodialysis must congregate for care three times weekly.2 Existing social disparities among disproportionate...

10.2215/cjn.0000000000000091 article EN Clinical Journal of the American Society of Nephrology 2023-01-30

Applications to the Fellowship Match through National Resident Matching Program (NRMP) Specialties Service (SMS) are at an all-time high. Data regarding preparedness of medical residents who go interview process is limited.To assess whether implementation curriculum could improve resident for and performance during fellowship interviews.All third-year internal medicine (N = 18) Zucker School Medicine Hofstra/Northwell (Northwell) applying subspecialty participated in that comprised a...

10.1177/2382120519855939 article EN cc-by-nc Journal of Medical Education and Curricular Development 2019-01-01

BACKGROUND: Tenofovir alafenamide (TAF) is a new formulation of tenofovir disoproxil fumarate (TDF) that was approved in 2015. While clinical trial evidence suggests TAF has more favorable outcomes related to kidney injury and loss bone mineral density, also leads higher lipid levels compared with TDF. OBJECTIVES: To (a) determine prescribing rates TDF among recipients from 2014 2018 large academic health system (b) compare baseline patient characteristics those newly prescribed versus...

10.18553/jmcp.2020.26.12.1582 article EN Journal of Managed Care & Specialty Pharmacy 2020-11-30
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