Mihaela-Cristina Bunea

ORCID: 0000-0002-8014-528X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Silk-based biomaterials and applications
  • Conducting polymers and applications
  • Electrochemical sensors and biosensors
  • Advanced biosensing and bioanalysis techniques
  • Advanced Cellulose Research Studies
  • Advanced Materials and Mechanics
  • Molecular Sensors and Ion Detection
  • Biochemical and Molecular Research
  • Plasmonic and Surface Plasmon Research
  • Advanced materials and composites
  • Collagen: Extraction and Characterization
  • Acute Lymphoblastic Leukemia research
  • Optical Coatings and Gratings
  • Wound Healing and Treatments
  • Antimicrobial Peptides and Activities
  • Electrohydrodynamics and Fluid Dynamics
  • Powder Metallurgy Techniques and Materials
  • Arsenic contamination and mitigation
  • Protein Degradation and Inhibitors
  • Injection Molding Process and Properties
  • Bone Tissue Engineering Materials
  • Dielectric materials and actuators
  • Biochemical effects in animals
  • TiO2 Photocatalysis and Solar Cells

National Institute of Materials Physics
2021-2024

Institut de Recherche Dupuy de Lôme
2022

Universitatea Națională de Știință și Tehnologie Politehnica București
2015-2021

The quality of life patients with chronic wounds can be extremely poor and, therefore, over the past decades, great efforts have been made to develop efficient strategies improve healing process and social impact associated these conditions. Cell based therapy, as a modern tissue engineering strategy, involves design 3D cell-scaffold bioconstructs obtained by preseeding drug loaded scaffolds undifferentiated cells in order achieve situ functional de novo tissue. This paper reports on...

10.1155/2015/195096 article EN cc-by Stem Cells International 2015-01-01

This study presents the design and manufacture of metasurface lenses optimized for focusing light with 1.55 µm wavelength. The are fabricated on silicon substrates using electron beam lithography, ultraviolet-nanoimprint lithography cryogenic deep reactive-ion etching techniques. designed makes use geometrical phase principle consists rectangular pillars target dimensions height h = 1200 nm, width w 230 length l 354 nm periodicity p 835 nm. simulated efficiency lens is 60%, while master...

10.3390/nano11092329 article EN cc-by Nanomaterials 2021-09-07

Due to the great significance of amino acids, a substantial number research studies has been directed toward development effective and reliable platforms for their evaluation, detection, identification. In order support these studies, new electrochemical platform based on PANI/ZnO nanowires' modified carbon inks screen-printed electrodes was developed qualitative analysis electroactive with emphasis tyrosine (Tyr) tryptophan (Trp). A comparative investigation ink before after modification...

10.3390/ijms24021129 article EN International Journal of Molecular Sciences 2023-01-06

The paper is focused on designing a novel silk fibroin-magnetite biomaterial scaffold for wounds healing in terms of: synthesis, physico-chemical and morphological characterization vitro biological behaviour assessment. Magnetic scaffolds were prepared from fibroin solutions magnetic nanoparticles with various concentrations by solvent casting technique. Specimens investigated FTIR-ATR spectroscopy XRD measurements. Morphological investigation including internal structure was employed AFM...

10.37358/mp.17.1.4791 article EN Materiale Plastice 2017-03-30

The electrochemical behavior and the interaction of immunosuppressive drug azathioprine (AZA) with deoxyribonucleic acid (DNA) were investigated using voltammetric techniques, mass spectrometry (MS), scanning electron microscopy (SEM). redox mechanism AZA on glassy carbon (GC) was cyclic differential pulse (DP) voltammetry. It proven that electroactive center is nitro group its reduction a diffusion-controlled process, which occurs in consecutive steps formation products involves transfer...

10.3390/ijms22136805 article EN International Journal of Molecular Sciences 2021-06-24

Bortezomib is an inhibitor of proteasomes and anti-cancer drug. Although bortezomib considered a safe drug, as confirmed by cytotoxicity assays, recent reports highlighted the possibility interaction between cellular components, with detrimental long-term effects. The evaluation dsDNA was investigated in bulk solution using electrochemical biosensor. binding to involved its electroactive centers led small morphological modifications double helix, which were electrochemically identified...

10.3390/molecules28073277 article EN cc-by Molecules 2023-04-06

The present work reports a new configuration of soft artificial muscle based on web metal covered nylon 6/6 micrometric fibers attached to thin polydimethylsiloxane (PDMS) film. preparation process is simple and implies the attachment metalized fiber networks PDMS sheet substrate while heating applying compression. resulting composite versatile can be cut in different shapes as function application sought. When an electric current passes through metallic web, heat produced, leading local...

10.1038/s41598-022-16872-2 article EN cc-by Scientific Reports 2022-07-29

Abstract A novel scaffold for in situ electrochemical detection of cell biomarkers was developed using electrospun nanofibers and commercial adhesive polymeric membranes. The sensing requires the cultivation cells on/near (bio)sensor surface a manner to preserve an appropriate electroactive available avoid passivation sensor damage. This can be achieved by employing biocompatible nanofiber meshes that allow have normal behavior do not alter detection. For better mechanical stability ease...

10.1007/s00604-024-06523-w article EN cc-by Microchimica Acta 2024-06-29

Azathioprine (AZA) is a pharmacologic immunosuppressive agent administrated in various conditions such as autoimmune disease or to prevent the rejection of organ transplantation. The mechanism action based on its biologically active metabolite 6-mercaptopurine (6-MP), which converted, among others, into thioguanine nucleotides capable incorporating replicating DNA, may act strong UV chromophore and trigger DNA oxidation. interaction between azathioprine before after exposure solar simulator...

10.3390/ijms232214438 article EN International Journal of Molecular Sciences 2022-11-20
Coming Soon ...