A5031746496- Sexual Differentiation and Disorders
- Diabetes Management and Research
- Diabetes and associated disorders
- Adrenal Hormones and Disorders
- Hormonal and reproductive studies
- Vector-borne infectious diseases
- Pancreatic function and diabetes
- Growth Hormone and Insulin-like Growth Factors
- Viral Infections and Vectors
- Metabolism and Genetic Disorders
- Thermography and Photoacoustic Techniques
- Hormonal Regulation and Hypertension
- Congenital Diaphragmatic Hernia Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Semiconductor Lasers and Optical Devices
- Calibration and Measurement Techniques
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Birth, Development, and Health
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Spectroscopy and Laser Applications
- Mycotoxins in Agriculture and Food
- Diabetes Treatment and Management
- Diet, Metabolism, and Disease
- Photoacoustic and Ultrasonic Imaging
Tel Aviv University
2014-2024
Tel Aviv Sourasky Medical Center
2014-2024
University of Debrecen
2024
Schneider Children's Medical Center
2019-2020
Sheba Medical Center
2019
Universidade Federal de Uberlândia
2014
Hebrew University of Jerusalem
1996-2013
Bnai Zion Medical Center
2013
Aflatoxins are carcinogenic metabolites produced by several members of the Aspergillus flavus group in grains and floods. Three genes, ver-1, omt-1, apa-2, coding for key enzymes a regulatory factor aflatoxin biosynthesis, respectively, have been identified, their DNA sequences published. In present study, three primer pairs, each complementing portion one were generated. extracted from mycelia five species, four Penicillium two Fusarium species was used as PCR template pairs. peanut, corn,...
Summary Objective Nonclassic congenital adrenal hyperplasia ( NCAH ) is common among Ashkenazi Jews (1:400). It associated with various degrees of postnatal virilization, irregular menses and infertility. Therapy symptomatic subjects consists physiologic doses glucocorticoids. The objective this study was to evaluate the effect glucocorticoid treatment on fertility pregnancy outcome in women . Design, Setting Patients This retrospective included 75 diagnosed who were followed our clinic...
Congenital adrenal hyperplasia (CAH) was among the first genetic disorders included in newborn screening (NBS) programs worldwide, based on 17α-hydroxyprogesterone (17-OHP) levels dried blood spots. However, success of NBS for CAH is hampered by high false positive (FP) rates, especially preterm and low-birthweight infants. To establish a set cutoff values adjusting both gestational age (GA) birthweight (BW), with aim reducing FP rates. This cross-sectional, population-based study summarizes...
Women with type 1 diabetes (T1D) are more susceptible than men to cardiovascular disease (CVD). Signs of increased risk may already appear among adolescent girls.
To determine whether nonclassical 21-hydroxylase deficiency (NC21OHD) compromises adult height (AH), and to establish the clinical parameters affecting AH in subjects with NC21OHD.This is a multicenter, retrospective review of medical records for biochemical parameters. The corrected (CH) standard deviation score (SDS), defined as SDS minus mean parental (MPH) SDS, was calculated each patient, where MPH average father's mother's SDS.The study group consisted 122 NC21OHD whose median age at...
It is clear that infrared transmitting fibers of high quality, with many uses in IR optical systems, can be fabricated from silver halide crystals. The process requires ultrapure starting material and control extrusion parameters such as temperature pressure. Under laboratory conditions, have been produced are usefully transparent 2-25 /spl mu/m a loss coefficient less than O.2 dB/m at 10.6 mu/m. These flexible, repeatedly bent into small radii circles without transmission. nontoxic,...
To assess the efficacy of rifampicin in achieving clinical and haematological recovery clearing infection dogs with experimentally induced acute monocytic ehrlichiosis.Five Ehrlichia canis-infected Beagle were treated (10 mg/kg/24 h orally for 3 weeks), nine E. received no treatment (infected untreated dogs) two served as uninfected controls. Clinical score, platelet counts, immunofluorescent antibody titres PCR detection canis-specific DNA blood, bone marrow spleen aspirates evaluated on...
Background: Normative data have been established for stimulated serum total cortisol in children but not free cortisol. Methods: Children who were referred ACTH testing to rule out adrenal insufficiency enrolled. Only with normal response and androgen levels included. Total was determined by a chemiluminescence method, measured the same method following equilibrium dialysis. Results: The study group consisted of 85 subjects (28 male; 57 female) median age 8.5 years (range 0.6-17.7). mean...
Abstract Background This study summarizes the results of prenatal diagnosis due to a history de novo mutation in previous pregnancy, tertiary center Israel, over 10‐year period. Methods We sorted all cases mutations from pool 2,260 pregnancies for which molecular was applied, between years 2008 and 2017. identified 122 performed mutations, 90 women. Results While total number yearly diagnoses stayed stable, linear increase detected procedure done mutation: 3 24 The most common diseases were...
Abstract Background Advances in treatment could mitigate the expected adverse changes body composition of children and adolescents with type 1 diabetes (T1D). Objectives To examine evolution weight status their association glycaemic control partial clinical remission youth T1D. Methods Ninety‐nine participants T1D (median age 9.5 years [interquartile range 7.3, 12.9], 59.6% boys) were longitudinally followed for 3 since diagnosis. Data at seven pre‐determined time points extracted from...
An otherwise healthy 17-year-old boy presented to the paediatric emergency department with acute severe epigastric pain. admission abdominal radiograph demonstrated gastric dilation, associated an elevated left hemidiaphragm. Subsequent barium contrast imaging confirmed diagnosis of organoaxial volvulus (AGV). Emergent exploratory laparoscopy revealed AGV migration stomach, spleen, pancreatic tail, splenic flexure, kidney and adrenal through a left-sided Bochdalek diaphragmatic hernia....
Background Treated or untreated non-classic congenital adrenal hyperplasia (NCCAH) diagnosed in childhood could pose an increased risk of obesity and metabolic derangements adolescence early adulthood. We aimed to explore the interaction between muscle-to-fat ratio (MFR) components syndrome pediatric subjects with NCCAH. Methods This retrospective observational study was conducted Tel Aviv Medical Center from January 2018 2022. The group comprised 75 (26 males) NCCAH (61...
Polyclonal antibodies (PAb) were raised against an aflatoxigenic strain of Aspergillus parasiticus by using two different sources for antibody elicitation: (i) filtrate a culture on which the fungus had been grown (ii) and chimeric proteins, expressed in Escherichia coli as separate products, genes ver-1 apa-2, are involved aflatoxin biosynthesis. The gene products amplified PCR, each was cloned into E. expression vector pGEX2T. Upon induction, bacteria overexpressed 38- 33-kDa proteins...
Abstract Background. A correlation between prenatal and postnatal penile clitoral sizes has not been reported. These data would substantiate the ability of ultrasound (US) scan to predict measurements. The aims were correlate measurements ascertain possible advantage using width rather than length Methods. This was a longitudinal study. Fetal penis clitoris measured by high‐resolution US gestational weeks 14 29. Postnatal external genitalia performed during first week. All twice...
Background: Severe hypoglycemic events are a major consequence of tight diabetes control. Continuous glucose monitoring systems (CGMSs) were recently introduced in order to minimize the risk hypoglycemia. However, present CGMSs invasive and costly have been demonstrated be intolerant for most children adolescents. Hence there is need simple, noninvasive, convenient, inexpensive device detect events. The Gili Medical Hypoglycemia Non Invasive Monitoring System (GMHNIMS) (Gili Ltd., Migdal...
Abstract Background Younger age at diagnosis of type 1 diabetes (T1D) may affect the clinical course and outcome. We examined whether was associated with glycemic control metabolic outcome in young adulthood. Methods This observational study included 105 adults T1D (current mean age: 21.2 ± 3.0 years, 12.0 4.0 years) followed during 2012 to 2019. Data on HbA1c, glucose variability, continuous monitoring (CGM) metrics, body mass index (BMI), blood pressure (BP), composition were collected...