A5088257778- Cardiomyopathy and Myosin Studies
- Tea Polyphenols and Effects
- GDF15 and Related Biomarkers
- Williams Syndrome Research
- Cardiac Fibrosis and Remodeling
- Congenital heart defects research
- Nutrition and Health in Aging
- Cardiovascular Effects of Exercise
China International Science and Technology Cooperation
2024
Chongqing Medical University
2019-2024
Children's Hospital of Chongqing Medical University
2019-2024
People's Hospital of Bishan District
2022-2024
Our previous studies have demonstrated that Ca2+ desensitizing catechin could correct diastolic dysfunction in experimental animals with restrictive cardiomyopathy. In this study, it is aimed to assess the effects of green tea extract on cardiac function and other clinical features pediatric patients cardiomyopathies. Twelve cardiomyopathy were enrolled for study. Echocardiography, ECG, laboratory tests performed before after administration 12 months. Comparison has been made these treatment...
To investigate the mechanisms of potential cardioprotective effects epigallocatechin-3-gallate (EGCG) in pressure overload-induced cardiac dysfunction.A chronic heart failure model was established using abdominal aortic constriction (AAC) surgery, rats were divided into sham, AAC, and AAC + EGCG groups. Echocardiography tissue section staining performed to evaluate function pathology, respectively. Gene expression level detected with quantitative real-time polymerase chain reactions....
Cardiomyopathy (CM) is a heterogeneous group of myocardial diseases in children. This study aimed to identify demographic features, clinical presentation and prognosis children with CM. Clinical characteristics prognostic factors associated mortality were evaluated by Cox proportional hazards regression analyses. Genetic testing was also conducted on portion patients. Among the 317 patients, 40.1%, 25.2%, 24.6% 10.1% diagnosed dilated cardiomyopathy (DCM), hypertrophic (HCM), left...
Aging is an independent risk factor for cardiovascular diseases. Cardiac diastolic dysfunction (CDD), ultimately leading to heart failure with preserved ejection fraction, prevalent among older individuals. Although therapeutics have made great progress, preventive strategies remain unmet medical needs. Green tea catechins been shown be effective in improving aging-related and cerebral disorders animal models patients. However, little attention has paid whether long-term administration of...
Abstract Background: Cardiomyopathy (CM) is a heterogeneous group of myocardial diseases in children. This study aimed to identify demographic features, clinical presentation and prognosis children with CM. Methods: Clinical characteristics prognostic factors associated mortality were evaluated by Cox proportional hazards regression analyses. Genetic testing was also conducted on portion patients. Results: Among the 317 patients, 40.1%, 25.2%, 24.6%, 10.1% diagnosed dilated cardiomyopathy...