A5072918507- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Drug Transport and Resistance Mechanisms
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Helminth infection and control
- Ginger and Zingiberaceae research
- Child Nutrition and Water Access
- Vector-borne infectious diseases
- Vector-Borne Animal Diseases
- Drug-Induced Hepatotoxicity and Protection
- Phytochemicals and Medicinal Plants
- Dermatological diseases and infestations
- Parasitic infections in humans and animals
- Natural Compound Pharmacology Studies
- Gallbladder and Bile Duct Disorders
- Natural Compounds in Disease Treatment
- Dengue and Mosquito Control Research
- Sperm and Testicular Function
- Peptidase Inhibition and Analysis
- Galectins and Cancer Biology
- Cancer, Lipids, and Metabolism
- Moringa oleifera research and applications
- Synthesis of Organic Compounds
- Pineapple and bromelain studies
- Food Industry and Aquatic Biology
Khon Kaen University
2012-2024
Rajamangala University of Technology Isan
2015-2024
Sakon Nakhon Rajabhat University
2015-2023
Despite the existence of effective anthelmintics, parasitic infections remain a major public health problem in Southeast Asia, including Thailand. In rural communities, continuing infection is often reinforced by dietary habits that have strong cultural basis and poor personal hygiene sanitation. This study presents survey prevalence intestinal among people The community-based cross-sectional was conducted villages Khon Kaen Province, northeastern Thailand, from March to August 2013. A total...
Intestinal parasitic infections are still a crucial problem among communities in Northeast Thailand. Misuse of antiparasitic drugs and unhealthy food behaviors known. This study aimed to explore the prevalence, behavioral health factors, motivation for self-treatment anti-parasitic this area. A community-based cross-sectional was conducted Phra Lap sub-district, Mu Khon Kaen district, province, Thailand, 2016. total 419 participants were recruited complete self-administered questionnaire...
This research aims to study the efficacy of Cinnamomum verum (Cv) extracts for ovicidal, larvicidal, and repellent activities against Culex quinquefasciatus mosquito vectors. The active components C. or cinnamon oil by Gas Chromatography (GC) analysis showed highest cinnamaldehyde at 83.53%. For ovicidal assay, essential concentrations 12.5, 25 50 ppm 72 h had 100% egg hatch inhibition a significant difference when compared control group (p<0.05). Larvicidal activity that were highly...
We investigated the anti-cholangiocarcinoma effect of α-mangostin from Garcinia mangostana pericarp extract (GM) in a human cholangiocarcinoma (CCA) cell line and hamster CCA allograft model. In vitro, cells were treated with GM at various concentrations for different time periods; then cell-cycle arrest apoptosis evaluated using flow cytometry, metastatic potential wound healing assays. vivo, allografts GM, gemcitabine (positive control) placebo (negative 1 month; tumor weight volume...
The present study was performed to observe histopathological changes in tissues of Bithynia siamensis goniomphalos (Gastropoda, Bithyniidae) incubated crude extract solutions camellia (Camellia oleifera) seed and mangosteen (Garcinia mangostana) pericarp, furthermore estimate the molluscicidal effects 2 plant substances. Substantial numbers bithyniid snails were various concentrations solution for 24 hr. As positive control, niclosamide, a chemical molluscicide, used. findings observed...
Aspirin and other non-steroidal anti-inflammatory drugs reduce the risk of cancer due to their anti-proliferative apoptotic effects, which are important mechanisms for anti-tumor activity. Here, effect aspirin on human cholangiocarcinoma cells (KKU-214) underlying its action were explored. Cell proliferation was measured by sulforhodamine B (SRB) assay, while cell cycle distribution apoptosis determined flow cytometry. Western blotting used explore protein expression molecular anti-cancer...
Echinostomes are intestinal trematodes that infect a wide range of vertebrate hosts, including humans, in their adult stage and also parasitize numerous invertebrate cold-blooded hosts larval stages. The purpose this study was to compare Echinostoma malayanum parasite growth, worm recovery, body size worms, eggs per worm, gram feces, pathological changes the small intestine experimental animals. In study, 6-8-week-old male hamsters, rats, mice, gerbils were infected with echinostome...
Twenty provinces in northeastern Thailand were investigated for fluke metacercariae contamination pickled fish, or pla-som, during January –June 2016. A total of 129 fish shops randomly chosen. Samples digested with acid-pepsin and those found to be infected fed hamsters test infectivity. The results demonstrated that only 20.2% the pla-som samples (mc), at various levels (1 268 mc/kg). All recovered inactive, degenerated could not develop adults animal model. In conclusion, mc infection...
Haplorchis taichui is a trematode that can mature in the small intestine of mammals and birds, including humans. Larval stages occur various invertebrate cold-blooded vertebrate hosts. The purpose this study was to investigate parasite growth, worm recovery rate, body size adult worms, eggs per gram feces pathological changes experimental hamsters. In study, 6- 8-weekold male Syrian hamsters (Mesocricetus auratus) were each infected with 200 H.taichui metacercariae then sacrificed at weeks...
Cholangiocarcinoma (CCA) is a rare but highly fatal cancer for which the molecular mechanisms and diagnostic markers are obscure.We therefore investigated kinetic expression of isocitrate dehydrogenase-1 (IDH1), dehydrogenase-2 (IDH2) homogentisate 1,2-dioxygenase (HGD) during tumorigenesis O. viverrini infection-associated CCA in an animal model, confirmed down-regulation human cases opisthorchiasis-associated through real time PCR.Kinetic HGD, IDH1 IDH2 model infection-induced was...
The present study was designed to investigate cholangiocarcinoma (CCA) antibodies in hamster serum. Hamster CCA cell lines were processed using sodium dodecyl sulfate-polyacrylamide gel electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. A candidate biomarker confirmed by immunoprecipitation western blot, further analyzed ELISA sera from normal control hamsters, hamsters with opisthorchiasis various stages of CCA, as well patients healthy...
The current study was performed to determine the antioxidant, anti-inflammatory, and anti-cholangiocarcinoma (CCA) properties of