- Hernia repair and management
- Inflammatory Biomarkers in Disease Prognosis
- Intestinal and Peritoneal Adhesions
- Abdominal Trauma and Injuries
- Appendicitis Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Vascular Procedures and Complications
- Abdominal Surgery and Complications
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Esophageal and GI Pathology
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Gastric Cancer Management and Outcomes
- Trauma Management and Diagnosis
- Congenital Diaphragmatic Hernia Studies
- Metastasis and carcinoma case studies
- Pelvic and Acetabular Injuries
- Tracheal and airway disorders
- Foreign Body Medical Cases
- Pleural and Pulmonary Diseases
- Parasitic infections in humans and animals
- Pain Management and Placebo Effect
- Traumatic Ocular and Foreign Body Injuries
- Pneumothorax, Barotrauma, Emphysema
County Hospital
2024-2025
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2015-2024
Clinical Emergency Hospital Bucharest
2024
Morpho (United States)
2023
Spitalul Clinic Judetean de Urgenta Târgu Mureş
2021
Spitalul Clinic Judetean Mures
2017
Background: Numerous tools, including nutritional and inflammatory markers, have been evaluated as the predictors of poor outcomes in COVID-19 patients. This study aims to verify predictive role prognostic index (PNI), CONUT Score, markers (monocyte lymphocyte ratio (MLR), neutrophil (NLR), platelet (PLR), systemic (SII), Systemic Inflammation Response Index (SIRI), Aggregate (AISI)) cases deep vein thrombosis (DVT) acute pulmonary embolism (APE) risk, well mortality, Methods: The present...
Background: Numerous tools, including inflammatory biomarkers and lung injury severity scores, have been evaluated as predictors of disease progression the requirement for intensive therapy in COVID-19 patients. This study aims to verify predictive role [monocyte lymphocyte ratio (MLR), neutrophil (NLR), systemic index (SII), Systemic Inflammation Response Index (SIRI), Aggregate (AISI), interleukin-6 (IL-6)] total system score (TSS) need invasive mechanical ventilation (IMV) mortality...
Background: An arteriovenous fistula (AVF) is the first-line vascular access pathway for patients diagnosed with end-stage renal disease (ESRD). In planning access, it necessary to check diameters of venous and arterial components satisfactory long-term results. Furthermore, mechanism underlying maturation failure short-term patency in cases AVFs not fully known. This study aims verify predictive role inflammatory biomarkers (the neutrophil lymphocyte ratio (NLR), platelet (PLR), systemic...
Background: Numerous tools, including inflammatory biomarkers and lung injury severity scores, have been evaluated as predictors of thromboembolic events the requirement for intensive therapy in COVID-19 patients. This study aims to verify predictive role [monocyte lymphocyte ratio (MLR), neutrophil (NLR), platelet (PLR), systemic index (SII), Systemic Inflammation Response Index (SIRI), Aggregate (AISI)] CT Severity Score acute limb ischemia (ALI) risk, unit care (ICU) admission, mortality...
Background: In sudden cardiac deaths (SCD), visceral adipose tissue has begun to manifest interest as a standalone cardiovascular risk factor. Studies have shown that epicardial can be seen viable marker of coronary atherosclerosis. This study aimed evaluate, from forensic perspective, the correlation between body mass index (BMI), heart weight, and valvular atherosclerosis, left ventricular morphology, thickness (EAT) in deaths, establishing an increased EAT novel Methods: is retrospective...
Due to their similar imaging features, high-grade gliomas (HGGs) and solitary brain metastases (BMs) can be easily misclassified. The peritumoral zone (PZ) of HGGs develops neoplastic cell infiltration, while in BMs the PZ contains pure vasogenic edema. As two PZs cannot differentiated macroscopically, this study investigated whether computed tomography (CT)-based texture analysis (TA) reflect histological difference between entities. Thirty-six patients with tumors (HGGs, n = 17; BMs, 19)...
Colecistita acută (AC) reprezintă o problemă de sănătate publică, crescând costurile spitalizare, determinate, în special, tratamentul chirurgical al acestor pacienţi.Colecistectomia laparoscopică (LC) a devenit gold-standardul terapeutic, însă momentul intervenţiei: precoce (ELC) versus întârziată (DLC), rămâne încă dezbătut.Obiectivul studiului vizează evaluarea rezultatelor postoperatorii între ELC şi DLC.Subsidiar, au fost evaluate rezultatele din perioada prepandemică, comparativ cu...
Background: Angiopoietin-2 (ANGPT2) and cell migration-inducing protein (CEMIP) are key regulators of angiogenesis, extracellular matrix remodeling, metastatic progression in various cancers, including lung cancer (LC). The presence these biomarkers vesicles (EVs) may offer valuable insights into the molecular mechanisms underlying LC metastasis. Extracellular play a critical role by enhancing intercellular communication supporting processes such as immune evasion, metastasis, transferring...
Background: Arteriovenous fistula dysfunction is a widely disputed subject in the scientific literature on end-stage kidney disease (ESKD). The main cause of mortality and morbidity these patients non-maturation or arteriovenous fistula. Despite many complications, native remains gold standard treatment requiring renal replacement. This study aims to discuss predictive role some systemic inflammatory biomarkers (NLR, PLR, SII, IL-6), intimal hyperplasia, neoangiogenesis (characterized by...
Background and Objectives: Defined by chronic pain, rheumatic diseases are often co-occurring with anxiety depression. Among the available psychological interventions, cognitive-behavioral therapies have an already-proven efficiency in these cases. However, need to adjust their structure became ubiquitous during post-pandemic period. Hence, objective of this study was investigate impact a single-session, process-based intervention for patients conditions within in-patient setting. Materials...
Chronic pain is associated with increased disability and vulnerability to emotional disorders. Personality psychological flexibility (PF) describe interindividual differences that shape the adjustment chronic pain. Specifically, PF was found be pain, fatigue, anxiety, depression intensity. Although previous studies established strong correlations between personality outcomes, evidence on nature of this relationship scarce. Therefore, objective study explore mediating effect distress. This...
Sudden cardiac death (SCD) is a significant global public health issue and the leading cause of worldwide. Its etiopathogenesis complex multilayered, involving dynamic factors interacting with preexistent cardiovascular pathology, frequently unknown, resulting in rhythm disorders arrest; Methods: This study conducted retrospective descriptive analysis over one-year period, identifying 321 autopsy cases sudden deaths from Institute Legal Medicine Mures County, Romania, 2019. From cases, 189...
Autologous native arteriovenous fistula (AVF) created in the non-dominant arm is gold standard vascular access for dialysis end-stage renal disease, but post-surgical dysfunction causes a reduction patient's quality of life. Creating functional upper extremity permanent limited by limb's resources, so good management complicated may improve patient outcomes. This article highlights importance new surgical options treating AVFs.We present case with 17-year-old complex radio-cephalic...
Background: Abdominal trauma is defined as a variety of injuries to the abdominal wall, solid or hollow intra-abdominal organs, and various vessels. Recently, there has been significant amount interest in establishment reliable biomarker that can predict outcome patients with an injury. The purpose this study confirm predictive role inflammatory biomarkers underlying risk factors acute kidney insufficiency (AKI) developing mortality patients; Materials methods: current was intended...
In this paper, we present the successful therapeutic approach of unresectable liver metastases in a patient with rectal cancer. A 63-year-old male underwent endoscopic polypectomy followed by rectosigmoid resection for an adenocarcinoma rectum diagnosed pT2N0 stage. The angio-computed tomography (CT) revealed four metastatic hepatic nodules ranging from 12 to 130 mm diameter. After one cure trans-arterial chemoembolization (TACE) lipiodol and 5-fluorouracil, combined FOLFOX4 + capecitabine...
(1) Background: Trauma is one of the leading causes death worldwide, with chest being third most frequent body part injured after abdominal and head trauma. Identifying predicting injuries related to trauma mechanism initial step in managing significant thoracic The purpose this study assess predictive capabilities blood count-derived inflammatory markers at admission. (2) Materials Methods: current was designed as an observational, analytical, retrospective cohort study. It included all...
Inflammation plays an important role in peripheral artery disease (PAD), contributing to the onset and progression of atherosclerosis, as well rupture atherosclerotic plaques. Studies have revealed that due their inflammatory nature, leucocytes play development atherosclerosis. A retrospective study was conducted involving 203 patients with PAD admitted Targu Mures Emergency County Hospital for revascularization surgery between January 2017 June 2019 (of which 47 were treated by endovascular...
Introduction Lung cancer is the leading cause of oncological deaths worldwide. Various combined inflammatory indexes, such as systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte (LMR), and platelet-to-lymphocyte (PLR) have shown associations with pretreatment survival prognosis in patients suffering lung or without brain metastases. This study aimed to compare average values NLR, PLR, LMR, SII healthy patients, any other metastases,...
The classical method of teaching human anatomy to students is based on the dissection cadavers. Nowadays, there are many ethical controversy regarding use cadavers during courses. In our study we tried get undergraduate students� opinion about some different techniques anatomy, including utility plastic models. We introduced in this 163 first year their at Faculty General Medicine from University and Pharmacy, Tirgu Mures. respondents were asked fill a 12-item anonymous questionnaire. Based...