- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Adipose Tissue and Metabolism
- Intraperitoneal and Appendiceal Malignancies
- Thyroid Cancer Diagnosis and Treatment
- Amoebic Infections and Treatments
- Appendicitis Diagnosis and Management
- Diagnosis and treatment of tuberculosis
- Ultrasound and Hyperthermia Applications
- Hernia repair and management
- Salivary Gland Tumors Diagnosis and Treatment
- AI in cancer detection
- Glioma Diagnosis and Treatment
- Salivary Gland Disorders and Functions
- Cardiovascular Disease and Adiposity
- Advanced X-ray and CT Imaging
- Urologic and reproductive health conditions
- Uterine Myomas and Treatments
- Neuroendocrine Tumor Research Advances
- Photoacoustic and Ultrasonic Imaging
- Urinary Bladder and Prostate Research
- Adipokines, Inflammation, and Metabolic Diseases
Iuliu Hațieganu University of Medicine and Pharmacy
2020-2024
Vienna General Hospital
2021-2023
Medical University of Vienna
2021-2023
Clinical Emergency Hospital Bucharest
2020-2023
Morpho (United States)
2020
Due to their similar imaging features, high-grade gliomas (HGGs) and solitary brain metastases (BMs) can be easily misclassified. The peritumoral zone (PZ) of HGGs develops neoplastic cell infiltration, while in BMs the PZ contains pure vasogenic edema. As two PZs cannot differentiated macroscopically, this study investigated whether computed tomography (CT)-based texture analysis (TA) reflect histological difference between entities. Thirty-six patients with tumors (HGGs, n = 17; BMs, 19)...
The classic ultrasonographic differentiation between benign and malignant adnexal masses encounters several limitations. Ultrasonography-based texture analysis (USTA) offers a new perspective, but its role has been incompletely evaluated. This study aimed to further investigate USTA’s capacity in differentiating from tumors, as well comparing the workflow results with previously-published research. A total of 123 lesions (benign, 88; malignant, 35) were retrospectively included. USTA was...
High-grade gliomas (HGGs) and solitary brain metastases (BMs) have similar imaging appearances, which often leads to misclassification. In HGGs, the surrounding tissues show malignant invasion, while BMs tend displace adjacent area. The edema produced by two cannot be differentiated conventional magnetic resonance (MRI) examinations. Forty-two patients with pathology-proven tumors who underwent pretreatment MRIs were retrospectively included (HGGs, n = 16; BMs, 26). Texture analysis of...
The ultrasonographic (US) features of endometriomas and hemorrhagic ovarian cysts (HOCs) are often overlapping. With the emergence new computer-aided diagnosis techniques, this is first study to investigate whether texture analysis (TA) could improve discrimination between two lesions in comparison with classic US evaluation. Fifty-six (endometriomas, 30; HOCs, 26) were retrospectively included. Four (low-level internal echoes, perceptible walls, no solid components, less than five locules)...
Background and Objectives: To assess ovarian cysts with texture analysis (TA) in magnetic resonance (MRI) images for establishing a differentiation criterion endometriomas functional hemorrhagic (HCs) that could potentially outperform their classic MRI diagnostic features. Materials Methods: Forty-three patients known who underwent were retrospectively included (endometriomas, n = 29; HCs, 14). TA was performed using dedicated software based on T2-weighted images, by incorporating the whole...
This study aimed to assess the effectiveness of MRI-based texture features lacrimal glands (LG) in augmenting imaging differentiation between primary Sjögren’s Syndrome (pSS) affected LG and healthy LG, as well emphasize possible importance radiomics pSS early-imaging diagnosis. The MRI examinations 23 patients diagnosed with controls were retrospectively included. Texture both extracted from a coronal post-contrast T1-weighted sequence, using dedicated software. ability discriminate was...
The imaging diagnosis of malignant ovarian cysts relies on their morphological features, which are not always specific to malignancy. histological analysis these shows fluid characteristics, cannot be assessed by conventional techniques. This study investigates whether the texture-based radiomics (TA) magnetic resonance (MRI) images content within can function as a noninvasive tool in differentiating between benign and lesions. Twenty-eight patients with (n = 15) 13) who underwent MRI...
Background: The purpose of this study was to assess the effectiveness radiomic analysis contrast-enhanced spectral mammography (CESM) in discriminating between breast cancers and background parenchymal enhancement (BPE). Methods: This retrospective included 38 patients that underwent CESM examinations for clinical purposes January 2019–December 2020. A total 57 malignant lesions 23 with 31 regions BPE were assessed through using MaZda software. parameters demonstrated be independent...
The morphological changes advocating for peritoneal carcinomatosis are inconsistent and may be visible only in later stages of the disease. However, malignant ascites represents an early sign, this fluid exhibits specific histological characteristics. This study aimed to quantify properties on computed tomography (CT) images intraperitoneal effusions through texture analysis evaluate its utility differentiating benign collections. Fifty-two patients with histologically proven (n=29) (n=23)...
Pathological analysis of ovarian cysts shows specific fluid characteristics that cannot be standardly evaluated on computer tomography (CT) examinations. This study aimed to assess the cysts’ attenuation values native (Np), arterial (Ap), and venous (Vp) contrast phases seventy patients with who underwent CT examinations were retrospectively included in this study. Patients divided according their final diagnosis into benign group (n = 32) malignant 38; which 27 primary 11 secondary...
The purpose of this study was to evaluate the diagnostic performance radiomic features extracted from standardized hybrid contrast-enhanced ultrasound (CEUS) data for assessment hormone receptor status, human epidermal growth factor 2 (HER2) tumor grade and Ki-67 in patients with primary breast cancer. This prospective included 72 biopsy-proven cancer who underwent CEUS examinations between October 2020 September 2021. A analysis found WavEnHH_s_4 parameter as an independent predictor...
The purpose of this study was to assess whether total tumor diameter (TTD) and multifocality are predictors for metastatic disease in papillary thyroid microcarcinomas (PTMC). Eighty-two patients with histologically proven PTMC were retrospectively included. Patients divided according the presence (n = 41) non-metastatic demographic-matched group. morphological features PTMCs (primary diameter, multifocality, TTD, number foci, site) compared between groups using univariate, multivariate,...
The commonly used magnetic resonance (MRI) criteria can be insufficient for discriminating mucinous from non-mucinous pancreatic cystic lesions (PCLs). histological differences between PCLs’ fluid composition may reflected in MRI images, but cannot assessed by visual evaluation alone. We investigate whether additional quantitative parameters such as signal intensity measurements (SIMs) and radiomics texture analysis (TA) aid the differentiation PCLs. Fifty-nine PCLs (mucinous, n = 24;...
The magnetic resonance (MRI) diagnosis of chronic prostatitis (CP) is insufficiently evaluated.To evaluate the MRI appearance CP in young patients by comparing it to individuals with non-prostatic related pathology.The study included 47 prostatitis-like symptoms evaluated urologists and referred pelvic examination (mean age=40.23±7 years; age range=23-49 years) 93 age-matched pathology age=37.5±7 range=21-49 years). All examinations were performed on a 1.5-T machine using prostate-specific...
The ability of texture analysis (TA) features to discriminate between different types infected fluid collections, as seen on computed tomography (CT) images, has never been investigated. study comprised forty patients who had pathological post-operative collections following gastric cancer surgery and underwent CT scans. Patients were separated into six groups based advanced microbiological the fluid: mono bacterial (n = 16)/multiple-bacterial 24)/fungal 14)/non-fungal 26) infection drug...
The conventional magnetic resonance imaging (MRI) evaluation and staging of cervical cancer encounters several pitfalls, partially due to subjective evaluations medical images. Fifty-six patients with histologically proven malignancies (squamous cell carcinomas,
Non-Hodgkin Lymphoma (NHL) represents a severe complication and the main cause of morbidity in patients with primary Sjögren's syndrome (pSS). This study aimed to assess role textural analysis (TA) revealing lymphoma-associated imaging parameters parotid gland (PG) parenchyma pSS. retrospective included total 36 (54.93 ± 13.34 years old; 91.6% females) diagnosed pSS according American College Rheumatology European League Against Rheumatism criteria (24 subjects no lymphomatous proliferation;...
Background and aims. The conventional computed tomography (CT) appearance of ovarian cystic masses is often insufficient to adequately differentiate between benign malignant entities. This study aims investigate whether texture analysis the fluid component can augment CT diagnosis tumors. Methods. Eighty-four patients with adnexal lesions who underwent examinations were retrospectively included. All had a final that was established by histological in forty four cases. features content...
Background and Objective: The imaging differentiation of benign from malignant intraperitoneal collections (IPCs) relies on the tumoral morphological modifications peritoneum, which are not always advocating for malignancy. We aimed to assess ascitic fluid with apparent diffusion coefficient (ADC) determine non-invasive, stand-alone, criteria effusions. Materials Methods: Sixty-one patients known IPCs who underwent magnetic resonance examinations reasons such as tumor staging, undetermined...
Intraperitoneal fluid accumulations are a common matter in current clinical practice, being encountered by most medical and surgical fields.To assess ascites with attenuation values the form of Hounsfield units (HU) order to determine non-invasive differentiation criterion for diagnosis intraperitoneal collections.Sixty patients known intra-peritoneal collections who underwent computed tomography (CT) reasons such as tumor staging, post-surgical follow-up or other indications, were...
Endometriomas and functional hemorrhagic cysts (FHCs) are a common gynecological encounter.This study aimed to assess the diagnostic efficiency of magnetic resonance imaging (MRI) using signal intensity measurements in differentiating endometriomas from FHCs.Forty-six patients who underwent pelvic MRI examinations (endometriomas, n=28; FHCs, n=18) were retrospectively included. The "T2 shading" sign was evaluated subjectively quantitatively by measuring T1-T2 difference calculating...
Several computed tomographic (CT) imaging features have been proposed to describe the infection of postoperative abdominal fluid collections; however, these are vague, and there is a significant overlap between infected non-infected collections. We assessed role textural parameters as additional diagnostic tools for distinguishing peritoneal collections in patients operated gastric cancer.From 527 cancer, we retrospectively selected 82 cases with intraperitoneal who underwent CT exams. The...