A5013286863- Advanced Chemical Physics Studies
- Celiac Disease Research and Management
- Microscopic Colitis
- Cold Atom Physics and Bose-Einstein Condensates
- Spectroscopy and Quantum Chemical Studies
- Photochemistry and Electron Transfer Studies
- Eosinophilic Esophagitis
- Quantum, superfluid, helium dynamics
- Laser-Matter Interactions and Applications
- Quantum Chromodynamics and Particle Interactions
- Ion-surface interactions and analysis
- Catalytic Processes in Materials Science
- High-Energy Particle Collisions Research
- Quantum and electron transport phenomena
- Quantum optics and atomic interactions
- Particle physics theoretical and experimental studies
- Quantum Mechanics and Applications
- Quantum many-body systems
- Mass Spectrometry Techniques and Applications
- Physics of Superconductivity and Magnetism
- Autoimmune Bullous Skin Diseases
- Food Allergy and Anaphylaxis Research
- Environmental Toxicology and Ecotoxicology
- Topological Materials and Phenomena
- Inflammatory Bowel Disease
Stockholm University
2015-2025
AlbaNova
2009-2024
Uppsala University
2006-2018
KTH Royal Institute of Technology
1996-2018
Uppsala University Hospital
1999-2016
Science for Life Laboratory
2013
Karolinska University Hospital
1997-2008
Karolinska Institutet
1999-2008
Lund University
1999-2005
1928 Diagnostics (Sweden)
2005
Wheat, rye, and barley proteins induce celiac disease, an autoimmune type of gastrointestinal disorder, in genetically susceptible persons. Because the disease may be underdiagnosed, we estimated prevalence tested hypothesis that assays for serum autoantibodies can used to detect untreated positive findings correlate with specific HLA haplotypes.
The fractional quantum Hall effect, being one of the most studied phenomena in condensed matter physics during past thirty years, has generated many groundbreaking new ideas and concepts. Very early on it was realized that zoo emerging states would need to be understood a systematic manner. first attempts do this, by Haldane Halperin, set an agenda for further work which continued this day. Since time idea hierarchies quasiparticles condensing form been pillar our understanding physics. In...
The earliest contact between antigen and the innate immune system is thought to direct subsequent antigen-specific T cell response. We hypothesized that cells of system, such as natural killer (NK) cells, NK1.1+ (NKT cells), γ/δ may regulate development allergic airway disease. demonstrate here depletion (NK NKT cells) before immunization inhibits pulmonary eosinophil CD3+ infiltration well increased levels interleukin (IL)-4, IL-5, IL-12 in bronchoalveolar lavage fluid a murine model...
We analysed whether the quantification of autoantibodies against tissue transglutaminase could be used to predict mucosal destruction and disease severity in patients with gluten sensitivity.One hundred seventy coeliac (CD), comprising 52 children severe malabsorption (group I), 59 mild symptoms II), adults III), 134 dermatitis herpetiformis (DH), 131 controls, were studied. Serial serum samples groups I II on a gluten-free diet also included. Serum levels antibodies recombinant determined...
Progress in cancer biomarker discovery is dependent on access to high-quality biological materials and high-resolution clinical data from the same cases. To overcome current limitations, a systematic prospective longitudinal sampling of multidisciplinary data, blood tissue patients was therefore initiated 2010 by Uppsala Umeå Universities involving their corresponding University Hospitals, which are referral centers for one third Swedish population.Patients with selected types who treated at...
We present a consistent and unified study of the spectrum low-lying mesons, baryons, glueballs using MIT bag model, incorporating several improvements in model. correct for center-of-mass motion, use running coupling ${\ensuremath{\alpha}}_{s}(R)$, include self-energy terms quarks gluons confined cavity, get constant from model QCD vacuum. Our fit to meson baryon spectrum, including pion, is good predictions glueball are given.
The aim was to investigate age-dependent serum levels and occurrence of elevated celiac disease (CD)-related antibodies in young children, define the optimal serological procedure when selecting for small intestinal biopsy.Included were 428 children with biopsy verified CD (median age 16 months; range 7.5 months-14 years) 216 controls 2.7 years; 8.5 months-14.6 years). Immunoglobulin (Ig) A against gliadin (AGA-IgA), tissue transglutaminase (tTG-IgA), endomysium (EMA-IgA) analysed.Increased...
Objective. A prominent feature of inflammatory bowel disease (IBD) is the presence cells in gut mucosa, and which contribute to ongoing process. The aim study was evaluate fecal neutrophil, eosinophil, mast cell macrophage markers assessment activity patients with ulcerative colitis (UC). Methods. Twenty‐eight active UC; 4 proctitis, 16 left‐side 8 total colitis, were included study. Patient history, endoscopy histopathology examined serum samples evaluated at inclusion after weeks...
ABSTRACT The role of immunoglobulin A (IgA) anti-tissue transglutaminase antibodies (IgA-tTG) as predictors untreated celiac disease (CoD) is well documented, and the presence levels these are most accurately monitored with native or recombinant human antigens. However, IgA-deficient CoD patients not identified by IgA serology, conflicting results concerning diagnostic validity IgG against gliadin (IgG-AGA), endomysium (IgG-EmA), tTG (IgG-tTG) have been reported. aim present study was to...
We describe a method of analysis which allows for reconstructing the nonlinear disturbance high Q harmonic oscillator. When oscillator is driven with two or more frequencies, nonlinearity causes intermodulation drives, resulting in complicated spectral response. Analysis this spectrum one to approximate nonlinearity. The method, generally applicable measurements based on resonant detection, increases information content measurement without requiring large detection bandwidth, and optimally...
Previous studies have indicated that peripheral circulating markers of inflammation are elevated in women with polycystic ovary syndrome (PCOS), but thus far no concerning adipose tissue been published. The aim the study was to investigate whether patients PCOS display increased expression inflammatory tissue. Twenty overweight PCOS, 10 lean and 20 controls had subcutaneous fat biopsies blood samples taken. Adipose levels mRNA were determined by use real-time PCR. Overweight higher relative...
We have reinvestigated the excited state dynamics of cyclohexa-1,3-diene (CHD) with time-resolved photoelectron spectroscopy and fewest switches surface hopping molecular based on linear response time-dependent density functional theory after excitation to lowest lying ππ* (1B) state. The combination both experiment revealed several new results: First, progress one single surface. After an incubation time 35 ± 10 fs state, proceed ground in additional 60 fs, either via a conrotatory...
We exploit the analogy with quantum Hall (QH) system to study weakly interacting bosons in a harmonic trap. For $\ensuremath{\delta}$-function interaction potential ``yrast'' states $L>~N(N\ensuremath{-}1)$ are degenerate, and we show how this can be understood terms of Haldane exclusion statistics. present spectra for four eight particles obtained by numerical algebraic methods, demonstrate more general hard-core lifts degeneracies on yrast line. The exact wave functions $N=4$ compared...
Background: Highly discriminatory markers for celiac disease are needed to identify children with early mucosal lesions. The purposes of this study were evaluate the clinical potential circulating anti-tissue transglutaminase (tTG) immunoglobulin (Ig)A antibodies in diagnosis childhood and investigate extent autoreactivity these antibodies. Methods: Included retrospective samples from 22 biopsy-verified disease, 23 control subjects healthy without any known gastrointestinal or inflammatory...
Irritable bowel syndrome (IBS) and collagenous colitis (CC) share chronically recurring symptoms of altered habits associated with abdominal pain or discomfort. The aims the present study were to investigate whether inflammatory markers could be detected in faeces from patients IBS CC, elucidate such analyses used as non-invasive tools distinguish between these disorders.Stool samples obtained 18 46 20 healthy controls (HC). Eosinophil protein X (EPX), myeloperoxidase (MPO), tryptase,...
Tar is an undesirable byproduct of biomass gasification, which can be removed through catalytic reforming to syngas components. Iron a promising, abundant alternative highly active but toxic nickel catalysts. The results observed so far in studies with iron have been mixed. In this paper, the decomposition naphthalene, representative model compound tar, was studied on Fe(110) surface using temperature-programmed desorption (TPD), sum frequency generation spectroscopy (SFG), and X-ray...
In this work, we introduce a modified dip-and-pull ECXPS approach that offers new mechanistic insight into the alkaline CORR over Cu(111) single crystal surface. We tackle two major unresolved questions in mechanism persist literature. Firstly, address for methane formation on and show likely proceeds via atomic carbon, which subsequently couples, leading to accumulation of amorphous carbon Secondly, provide whether acetate occurs entirely surface or partially within solution phase, showing...
While Au electrooxidation in acidic aqueous media on a phenomenological level proceeds directly from Au(0) to Au(III), it has previously been suggested that Au(I) states are intermediate species of the oxidation mechanism. Here we add evidence for transient by probing operando pH=3 HClO4 electrolyte high energy resolution fluorescence detected X-ray absorption near-edge structure (HERFD-XANES) at potentials up 1.8 V vs reversible hydrogen electrode. The perchlorate ions used as sacrificial...
A recently developed method for predicting binding affinities in ligand–receptor complexes, based on interaction energy averaging and conformational sampling by molecular dynamics simulation, is presented. Polar nonpolar contributions to the free are approximated a linear scaling of corresponding terms average intermolecular bound states ligand. While originally assumed validity electrostatic response, we show that incorporation systematic deviations from response derived perturbation...
The resonance-enhanced surface second-harmonic generation (SHG) from a suspension of polystyrene microspheres was investigated as function particle size in range the order fundamental wavelength for two different second-harmonic-enhancing dyes---malachite green and pyridine 1. dyes gave same strongly modulated pattern forward scattering efficiency. Direct comparison to nonlinear Rayleigh-Gans-Debye (NLRGD) Wentzel-Kramers-Brillouin (NLWKB) model predictions showed that NLWKB reproduces...
Abstract. Objective. Analysis of antibodies against tissue transglutaminase (tTG) has been shown valuable in the diagnosis coeliac disease (CD) but how quickly serum titres decrease after introduction a gluten‐free diet (GFD) is not known adults. CD well‐recognized disorder amongst general population and many persons try GFD for fairly vague symptoms before they seek medical advice. Therefore, it important to determine time that serologic tests remain predictive GFD. Methods. Sera were taken...