A5030886603- Advanced battery technologies research
- Advanced Battery Materials and Technologies
- Immune Response and Inflammation
- Asthma and respiratory diseases
- Advancements in Battery Materials
- T-cell and B-cell Immunology
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Supercapacitor Materials and Fabrication
- Immune Cell Function and Interaction
- Electrocatalysts for Energy Conversion
- RNA and protein synthesis mechanisms
- Advanced biosensing and bioanalysis techniques
- Bacterial biofilms and quorum sensing
- Enzyme Structure and Function
- Neonatal Respiratory Health Research
- RNA Research and Splicing
- Wastewater Treatment and Nitrogen Removal
- DNA Repair Mechanisms
- Immunotherapy and Immune Responses
- Water Treatment and Disinfection
- Advanced Battery Technologies Research
- Microbial Fuel Cells and Bioremediation
- HIV/AIDS drug development and treatment
- Inhalation and Respiratory Drug Delivery
University College London
2022-2025
Twelfth Guangzhou City People's Hospital
2024
Imperial College London
2024
London Centre for Nanotechnology
2024
ECSI Fibrotools (United States)
2022
University of Nottingham Ningbo China
2021
Guangzhou First People's Hospital
2020
Guangzhou Medical University
2020
South China University of Technology
2020
Indiana University School of Medicine
2009-2019
Aqueous zinc-ion batteries (AZIBs) have experienced a rapid surge in popularity, as evident from the extensive research with over 30 000 articles published past 5 years. Previous studies on AZIBs showcased impressive long-cycle stability at high current densities, achieving thousands or tens of cycles. However, practical low densities (<1C) is restricted to merely 50-100 cycles due intensified cathode dissolution. This genuine limitation poses considerable challenge their transition...
The electrochemical effect of isotope (EEI) water is introduced in the Zn-ion batteries (ZIBs) electrolyte to deal with challenge severe side reactions and massive gas production. Due low diffusion strong coordination ions D
For zinc-ion batteries (ZIBs), the non-uniform Zn plating/stripping results in a high polarization and low Coulombic efficiency (CE), hindering large-scale application of ZIBs. Here, inspired by biomass seaweed plants, an anionic polyelectrolyte alginate acid (SA) was used to initiate situ formation high-performance solid electrolyte interphase (SEI) layer on anode. Attribute groups -COO
Aqueous zinc ions batteries (AZIBs) using non-organic electrolytes have garnered sustained interest as a future energy storage technology, primarily due to their low cost, environmental friendliness, and intrinsic safety. However, ion suffer from series of serious challenges, including hydrogen evolution reaction (HER) at the anode, surface passivation, dendrite formation, well limited operating voltage comparatively density. These factors are all influenced by concentration H+ in...
Zinc‐ion batteries (ZIBs), which are inexpensive and environmentally friendly, have a lot of potential for use in grid‐scale energy storage systems, but their is constrained by the availability suitable cathode materials. MnO 2 ‐based cathodes emerging as promising contenders, due to great safety, well device's stable output voltage platform (1.5 V). Improving slow kinetics caused low electrical conductivity mass diffusion rate challenge future next‐generation rapid charging devices. Herein,...
Abstract For zinc‐ion batteries (ZIBs), the non‐uniform Zn plating/stripping results in a high polarization and low Coulombic efficiency (CE), hindering large‐scale application of ZIBs. Here, inspired by biomass seaweed plants, an anionic polyelectrolyte alginate acid (SA) was used to initiate situ formation high‐performance solid electrolyte interphase (SEI) layer on anode. Attribute groups −COO − , affinity 2+ ions induces well‐aligned accelerating channel for uniform plating. This SEI...
Toll-like receptors (TLRs) recognize highly conserved microbial molecular patterns, such as found in endotoxin. This study tested whether TLR4 and TLR2 stimulation vivo would modulate subsequent adaptive (allergic) immune responses. We analyzed the effects of pulmonary administration a agonist, lipid A (LpA), two agonists, peptidoglycan (Ppg) PamCys, murine model allergic inflammation. The TLR agonists were administered during allergen sensitization or challenge. Both decreased...
T cell activation and cytokine secretion are important mediators of inflammation in allergic asthma. The costimulatory pathway CD28/CD80/CD86 has been shown to play an role cellactivation asthma, but less is known about the effect other molecules allergy. molecule OX40 ligand (OX40L), a member tumor necrosis factorsuperfamily, be priming production. We investigated OX40L murine model using OX40L–/– mice. In this model, following OVA sensitization challenge, mice develop features including...
Apurinic/apyrimidinic endonuclease (APE1) is an unusual nuclear redox factor in which the redox-active cysteines identified to date, C65 and C93, are surface inaccessible residues whose activities may be influenced by partial unfolding of APE1. To assess role five remaining APE1's activity, double-cysteine mutants were analyzed, excluding C65A, redox-inactive as a single mutant. C93A/C99A APE1 was found redox-inactive, whereas other retained same activity that observed for C93A determine...
Apurinic/apyrimidinic endonuclease I (APE1) is an essential base excision repair enzyme that catalyzes a Mg2+-dependent reaction in which the phosphodiester backbone cleaved 5′ of abasic site duplex DNA. This has been proposed to involve either one or two metal ions bound active site. In present study, we report crystal structures Mg2+, Mn2+, and apo-APE1 determined at 1.4, 2.2, 1.65 Å, respectively, representing highest resolution yet reported for APE1. our structures, single well-ordered...
Abstract Aqueous zinc-ion batteries offer a sustainable alternative to lithium-ion due their abundance, safety, and eco-friendliness. However, challenges like hydrogen evolution uncontrolled diffusion of H⁺, Zn²⁺, SO₄²⁻ in the electrolyte lead dendrite formation, side reactions, reduced Coulombic efficiency for Zn nucleation. Here, simultaneously regulate cations anions electrolyte, an ion-separation accelerating channel is constructed by introducing layer-by-layer self-assembly flocculant...
Background. Both animal models and clinical outcomes studies of transplantation suggest that antigen-independent mechanisms can alter graft survival function. It has been suggested processes interact with alloantigen-specific responses to augment the rejection reaction. A major link between antigen-specific adaptive immunity pro-inflammatory stimuli is innate immunity. During transplantation, may be stimulated by multiple factors, including ischemia, reperfusion, sterile injury, systemic...
Abstract Background Maternal atopic background and stimulation of the adaptive immune system with allergen interact in development allergic disease. Stimulation innate through microbial exposure, such as activation Toll-like-receptor 2 (TLR2), may reduce allergy childhood. However, little is known about immunological effects on early responses association maternal atopy. Methods We analyzed cord blood mononuclear cells (CBMC) from 50 healthy neonates (31 non-atopic 19 mothers). Cells were...
Abstract The electrochemical effect of isotope (EEI) water is introduced in the Zn‐ion batteries (ZIBs) electrolyte to deal with challenge severe side reactions and massive gas production. Due low diffusion strong coordination ions D 2 O, possibility decreased, resulting a broader electrochemically stable potential window, less pH change, zinc hydroxide sulfate (ZHS) generation during cycling. Moreover, we demonstrate that O eliminates different ZHS phases generated by change bound cycling...
Due to their potential for high energy density, low cost, and environmental sustainability, zinc-ion batteries (ZIBs) have emerged as a promising storage technology. The performance, safety, overall efficiency of ZIBs are significantly impacted by the properties electrolyte, such ionic conductivity, electrochemical stability window, viscosity, compatibility with other battery components. use liquids (ILs) in has gained extensive attention recent years due desirable properties, thermal...
A wealth of genetic information and some biochemical analysis have made the GAL regulon yeast Saccharomyces cerevisiae a classic model system for studying transcriptional activation in eukaryotes. Galactose induces this switch, which is regulated by three proteins: activator Gal4p, bound to DNA; repressor Gal80p; transducer Gal3p. We showed previously that NADP appears act as trigger kick off activator. Sustained involves complex Gal3p Gal80p mediated galactose ATP. solved crystal structure...
This research introduces a chemistry-agnostic approach to achieve rapid and degradation-free battery charging via ultrasonic agitation. An device operating in the megahertz range was used stimulate electrolyte flow from outside cell. The acoustic streaming effect accelerates ion transport bulk electrode surface suppresses formation of an depletion zone. experimental setup optically observe dendrites when current imposed across two zinc electrodes exceeded limiting beyond which diffusion...