A5094013556- Virus-based gene therapy research
- Vector-Borne Animal Diseases
- RNA regulation and disease
- Plant Virus Research Studies
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Virology and Viral Diseases
- Parvovirus B19 Infection Studies
- Antimicrobial Peptides and Activities
- Lipid Membrane Structure and Behavior
- RNA Interference and Gene Delivery
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
Consejo Nacional de Investigaciones Científicas y Técnicas
2024-2025
Universidad Nacional de Cuyo
2024-2025
Instituto Interdisciplinario de Ciencias Básicas
2024-2025
National Research Council
2025
Birnaviruses are a group of double-stranded RNA (dsRNA) viruses infecting birds, fish and insects. Early endosomes (EE) constitute the platform for viral replication. Here, we study mechanism birnaviral targeting EE membranes. Using Infectious Bursal Disease Virus (IBDV) as model, validate that protein 3 (VP3) binds to phosphatidylinositol-3-phosphate (PI3P) present in We identify domain VP3 involved PI3P-binding, named P2 localized core VP3, establish critical role arginine at position 200...
Birnaviruses are a group of double-stranded RNA (dsRNA) viruses infecting birds, fish, and insects. Early endosomes (EE) constitute the platform for viral replication. Here, we study mechanism birnaviral targeting EE membranes. Using Infectious Bursal Disease Virus (IBDV) as model, validate that protein 3 (VP3) binds to phosphatidylinositol-3-phosphate (PI3P) present in We identify domain VP3 involved PI3P-binding, named P2 localized core VP3, establish critical role arginine at position 200...
Abstract Birnaviruses are a group of double-stranded RNA (dsRNA) viruses infecting birds, fish and insects. Early endosomes (EE) constitute the platform for viral replication. Here, we study mechanism birnaviral targeting EE membranes. Using Infectious Bursal Disease Virus (IBDV) as model, validate that protein 3 (VP3) binds to phosphatidylinositol-3-phosphate (PI3P) present in We identify domain VP3 involved PI3P-binding, named P2 localized core VP3, establish critical role arginine at...
Birnaviruses form a distinct class of double-stranded RNA (dsRNA) viruses characterized by the absence transcription-competent inner core particle. The early endosomes (EE) cells infected with infectious bursal disease virus (IBDV) - prototypical birnavirus and an important avian pathogen constitute platform for viral replication. Here, we study mechanism birnaviral hijacking EE membranes this process. We demonstrate that protein 3 (VP3) specifically binds to phosphatidylinositol-3-phosphate...
Birnaviruses are a group of double-stranded RNA (dsRNA) viruses infecting birds, fish, and insects. Early endosomes (EE) constitute the platform for viral replication. Here, we study mechanism birnaviral targeting EE membranes. Using Infectious Bursal Disease Virus (IBDV) as model, validate that protein 3 (VP3) binds to phosphatidylinositol-3-phosphate (PI3P) present in We identify domain VP3 involved PI3P-binding, named P2 localized core VP3, establish critical role arginine at position 200...