- SARS-CoV-2 and COVID-19 Research
- Computational Drug Discovery Methods
- vaccines and immunoinformatics approaches
- Monoclonal and Polyclonal Antibodies Research
- Pharmacological Effects of Natural Compounds
- CRISPR and Genetic Engineering
- MicroRNA in disease regulation
- Herbal Medicine Research Studies
- Cloud Data Security Solutions
- Diverse Scientific Research Studies
- Insect and Pesticide Research
- Cancer therapeutics and mechanisms
- Blockchain Technology Applications and Security
- Poxvirus research and outbreaks
- Cancer-related Molecular Pathways
- Natural Antidiabetic Agents Studies
- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Food Science and Nutritional Studies
- Bioinformatics and Genomic Networks
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Ubiquitin and proteasome pathways
Vidyasagar University
2019-2025
Institute of Science and Technology
2022
Czech Academy of Sciences, Oriental Institute
2022
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Lumpy skin disease (LSD) is a transboundary virus that mostly affects cattle. It has recently been reported all over the world, which highlights need for efficient control methods. LSD poses serious economic dangers worldwide.
Purpose: Pandemic Novel Coronavirus (SARS-CoV-2) has emerger centered from wuhan, China. Structurally homologous spike protein of SARS-CoV-2 receptor is taxonomically with SARS-Cov and SARS associated bat coronavirus. Still now scientists are trying to find out proper vaccine treatments for this disease. Methods: Systematically we modeled compared the structure along Bat Cov, Cov Urbani. S1 S2 unit coronavirus attached ACE2 furin, here docked 5 Ca+ chelating drugs these two proteins....
Background: Due to the rapid rise of allergies, anti-allergy medications are commonly being utilised reduce inflammation; however, allergen-specific inhibitors may also be utilised. Objective: Our in silico study is aimed at finding out a promising anti-allergic compound that can act against wide range allergens. Methods: The inhibitory efficacies potential compounds were investigated by ADMET studies and followed high throughput molecular docking. Binding energy was calculated AUTODOCK,...
Abstract Background Recently, in Nov 2021, South Africa, the SARS CoV-2 variant Omicron was found to be highly infectious and transmissible but with least fatality. It occupies nasopharynx-oropharynx easily spreads. The epidemiological data/reports suggest that several vaccines failed neutralize Omicron. has a large number of spike mutations RNA/protein were developed from its predecessors may justify escape most neutralization reactions. It’s lower...
Pandemic coronavirus causes respiratory, enteric and sometimes neurological diseases. Proteome data of individual strains were already reported. Here we investigated SARS-CoV-2 ssRNA protein spike, envelope membrane to determine stress adaptation profile. Thermodynamic properties, Physicochemical behaviour and, amino acid composition along with their RMSD value was analysed. index SARS-CoV2 is unstable in higher temperature. Presence proportion polar positive negative charged residues into...