A5001862236- Wound Healing and Treatments
- Diet and metabolism studies
- Periodontal Regeneration and Treatments
- Gut microbiota and health
- Plant Parasitism and Resistance
- Tissue Engineering and Regenerative Medicine
- Pressure Ulcer Prevention and Management
- Essential Oils and Antimicrobial Activity
- Probiotics and Fermented Foods
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Consumer Attitudes and Food Labeling
- Immune Cell Function and Interaction
- Seaweed-derived Bioactive Compounds
- Curcumin's Biomedical Applications
- Metabolism, Diabetes, and Cancer
- Selenium in Biological Systems
- Diet, Metabolism, and Disease
- Neonatal and Maternal Infections
- Biochemical Acid Research Studies
- Electrospun Nanofibers in Biomedical Applications
- Medicinal Plant Research
- Nuclear Receptors and Signaling
- Bacterial biofilms and quorum sensing
- Dietary Effects on Health
Indiana University – Purdue University Indianapolis
2019-2024
Indiana University School of Medicine
2019-2024
McGowan Institute for Regenerative Medicine
2023-2024
University of Pittsburgh
2023-2024
Indiana University Health
2019-2024
Cook Biotech (United States)
2024
California Institute for Regenerative Medicine
2024
Centurion University of Technology and Management
2021-2024
The Ohio State University
2019
Comprehensive Clinical Research
2019
Objective: The objective of this work was to causatively link biofilm properties bacterial infection specific pathogenic mechanisms in wound healing. Background: Staphylococcus aureus is one the four most prevalent species identified chronic wounds. Causatively linking pathology challenging. Thus, isogenic mutant stains S. with varying degree formation ability studied an established preclinical porcine model infection. Methods: Isogenic strains ( ΔrexB > USA300 ΔsarA ) biofilm-forming...
Collagen containing wound-care dressings are extensively used. However, the mechanism of action these remain unclear. Earlier studies utilizing a modified collagen gel (MCG) dressing demonstrated improved vascularization ischemic wounds and better healing outcomes. Wound macrophages pivotal in facilitating wound angiogenesis timely healing. The current study was designed to investigate effect MCG on macrophage phenotype function. augmented recruitment at wound-site, attenuated...
The study explores the dynamic interconnections between selected macroeconomic factors and GDP growth in India using monthly time series data from 2012 to 2022. has employed regression, unit root test, cointegration, error correction method cumulative sum test after performing pre-tests like, tests for autocorrelation, serial correlation, multicollinearity, heteroscedasticity normality. found a significantly negative correlation all (except interest rate) with growth. regression could...
Macrophages assume diverse phenotypes and functions in response to cues from the microenvironment. Earlier we reported an anti-inflammatory effect of Collagenase Santyl® Ointment (CSO) active constituent CSO (CS-API) on wound macrophages resolving inflammation indicating roles beyond debridement healing. Building upon our prior finding, this study aimed understand subsets following treatment with CS-API. scRNA-sequencing was performed human blood monocyte-derived (MDM) CS-API for 24 h....
Hydrolyzed collagen-based matrices are widely used as wound care dressings. Information on the mechanism of action such dressings is scanty. The objective this study was to test effect a specific hydrolyzed collagen powder (HCP), which extensively for management in United States.
Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenemia, a quite common heterogenous endocrine/hormonal disorder, and accompanied elevated androgen level, menstrual irregularity, hirsutism. The consequences include infertility or miscarriage. It challenging problem to the physicians. In one-arm, non-randomized preliminary investigation in fifty premenopausal women, we demonstrated efficacy of Furocyst®, patented, standardized Trigonella foenum-graecum extract, ameliorating...
Abstract Uncontrolled fibrosis via excess deposition of extracellular matrix (ECM), is a hallmark hypertrophic scars and keloids. A decellularized ECM biomaterial from porcine small intestinal submucosa (SIS; Biodesign® or BioD, Cook Biotech, Inc.), widely used in clinical applications for tissue repair. The current study tested the effects BioD scaffolds, as compared with collagen constructs, on normal human skin (nFB) keloid fibroblasts (kFB). Real-time qPCR, ELISA, knockdown studies were...
Abstract Lemongrass ( Cymbopogon flexuosus ) essential oil (LGEO) contains α-citral, β-citral and other phytochemicals extracted using various methods. This research oils steam distillation (SD) microwave-assisted hydro (MAHD) to maximize quantity purity. LGEO was tested for antibacterial properties. SD compared MAHD output based on production chemical composition. We performed GCMS characterize LGEO. Fourier transform infrared spectroscopy (FTIR) used quantum analysis. Spectroscopic...