A5102018264- Fungal Plant Pathogen Control
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Synthesis of Organic Compounds
- Higher Education and Teaching Methods
- Polyoxometalates: Synthesis and Applications
- Carbohydrate Chemistry and Synthesis
- Insect-Plant Interactions and Control
- Plant-Microbe Interactions and Immunity
- Phytochemical compounds biological activities
- Advanced biosensing and bioanalysis techniques
- Plant-derived Lignans Synthesis and Bioactivity
- Magnetism in coordination complexes
- Cancer therapeutics and mechanisms
- DNA and Nucleic Acid Chemistry
- Metal-Organic Frameworks: Synthesis and Applications
- Traditional and Medicinal Uses of Annonaceae
Cell Technology (China)
2025
Liaocheng University
2020-2025
State Key Laboratory of Virology
2018
Wuhan University
2018
Guangzhou Railway Polytechnic
2012
Uppsala University
2009
Eastern Liaoning University
2006
Succinate dehydrogenase (SDH) has been identified as one of the most significant targets for fungicide discovery. To date, 23 commercial SDH inhibitor (SDHI) fungicides have approved plant protection since first launch carboxin in 1966, and extensively applied to combat destructive fungi.In this project, 20 novel pyridine sulfide derivatives containing SDH-based heterocyclic amide were designed, synthesized, characterized by proton nuclear magnetic resonance (1 H-NMR), carbon-13 (13 C)-NMR...
The development of new green fungicides based on the structural optimization natural products can effectively solve problems low safety and high pathogen resistance traditional fungicides. In this paper, pyrazole amide compound h-I-9 with excellent fungicidal activity discovered in previous work, a series l-serine-derived waltherione alkaloid-derived ester derivatives were synthesized. structures successively identified by 1H NMR, 13C high-resolution mass spectrometry, X-ray single-crystal...
A series of novel isatin‐coumarin derivatives tethered through ethylene were designed, synthesized, and evaluated for their in vitro antimycobacterial activities against Mycobacterium tuberculosis (MTB) H37Rv multidrug‐resistant (MDR‐TB). All hybrids exhibited potential MTB MDR‐TB with minimum inhibitory concentration (MIC) ranging from 32 to 256 μg/mL. In particular, the hybrid 4h (MIC: 50 μg/mL) was most active H 37 Rv strains, which 2 >4 folds more potent than first‐line antitubercular...
A new member of hexopyranosyl nucleoside family, methylene-bridged (BHNA), has been synthesized through generation carbon radical at C6' in (6'S-Me, 7'S-Me)-carba-LNA T nucleoside, followed by rearrangement to C4' which was quenched hydrogen atom give BHNA. The stereoelectronic requirement for this unusual elucidated chemical model building and ab intio calculations show that the coplanarity single electron occupied p-orbital with σ*O4'-C4' plays an important role reaction take place....
Structural optimization based on natural products is an important and effective way to discover new green pesticides. Here, two series of amide derivatives sinapic acid mycophenolic were designed in combination with the fungicidal product piperlongumine synthesized by preparing carboxylic into acyl chloride then reacting corresponding aromatic amines, respectively. The resulting structures successively characterized 1H NMR, 13 C HRMS. crystal molecules I-4 II-5 analyzed for structure...
Abstract Structural optimization based on natural products has become an effective way to develop new green fungicides, which provide important guiding significance for practicing the development concept and promoting of pesticides. In this project, combined with fungicidal amide lead compound X-I-4 discovered in our previous work piperazine derivatives reported literatures, target compounds containing 4-quinolone substructures waltherione F were designed, synthesized screened their...