ConspectusSelf-propelled chemical motors are chemically powered micro- or nanosized swimmers. The energy required for these motors' active motion derives from catalytic reactions and the transformation of a fuel dissolved in solution. While self-propulsion is now well established larger particles, it still unclear if enzymes, nature's nanometer-sized catalysts, potentially also self-powered nanomotors. Because its small size, any increase an enzyme's diffusion due to must be observed on top...

Plasmonic molecules are building blocks of metallic nanostructures that give rise to intriguing optical phenomena with similarities those seen in molecular systems. The ability design plasmonic hybrid structures and nanometric resolution would enable applications metamaterials sensing presently cannot be demonstrated, because a lack suitable fabrication methods allowing the structural control atoms on large scale. Here we demonstrate wafer-scale "lithography-free" parallel scheme realize...

Catalytically active colloids are model systems for chemical motors and matter. It is desirable to replace the inorganic catalysts toxic fuels that often used with biocompatible enzymatic reactions. However, compared catalysts, enzyme-coated tend exhibit less activity. Here, we show self-assembly of genetically engineered M13 bacteriophages bind enzymes magnetic beads ensures high localized These phage-decorated provide a proteinaceous environment directed enzyme immobilization. The...

Abstract Chiral plasmonic nanoparticles can exhibit strong chiroptical signals compared to the corresponding molecular response. Observations are, however, generally restricted measurements on stationary single particles with a fixed orientation, which complicates spectral analysis. Here, we report spectroscopic observation of freely diffusing chiral nanoparticle in solution. By acquiring time-resolved circular differential scattering show that interpretation is significantly simplified. We...

The diffusion of enzymes is fundamental importance for many biochemical processes. Enhanced or directed enzyme can alter the accessibility substrates and organization within cells. Several studies based on fluorescence correlation spectroscopy report enhanced upon interaction with their substrate inhibitor. In this context, major given to fructose-bisphosphate aldolase, which has been reported even though catalysed reaction endothermic. Additionally, tracer particles surrounding active...

Abstract Externally controlled microswimmers offer prospects for transport in biological research and medical applications. This requires biocompatibility of the swimmers possibility to tailor their propulsion mechanisms respective low Reynolds number environment. Here, we incorporate amounts biocompatible alloy iron platinum (FePt) its $$\hbox {L1}_{{0}}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mtext>L1</mml:mtext> <mml:mn>0</mml:mn> </mml:msub>...

The reported changes in self-diffusion of small molecules during reactions have been attributed to "boosted mobility". We demonstrate the critical role changing concentrations paramagnetic ions on nuclear magnetic resonance (NMR) signal intensities, which led erroneous measurements diffusion coefficients. present simple methods overcome this problem. use shuffled gradient amplitudes allows accurate NMR measurements, even with time-dependent relaxation rates caused by ions. addition a agent...

Enzyme-based biocatalysis exhibits multiple advantages over inorganic catalysts, including the biocompatibility and unchallenged specificity of enzymes towards their substrate. The recovery repeated use is essential for any realistic application in biotechnology, but not easily achieved with current strategies. For this purpose, are often immobilized on scaffolds, which could entail a reduction enzymes’ activity. Here, we show that immobilization to nano-scaled biological scaffold,...

The apparent “boosted mobility” observed by nuclear magnetic resonance (NMR) diffusion measurements is the result of a known artefact. When signal intensities are changing during an NMR measurement for reasons other than diffusion, use monotonically increasing gradient amplitudes produces erroneous coefficient values. We show that no boosted molecular mobility when shuffled applied.

The measured changes in self-diffusion of small molecules during reactions have been attributed “boosted mobility”. We demonstrate the critical role changing concentrations paramagnetic ions on nuclear magnetic resonance (NMR) signal intensities, which lead to erroneous measurements diffusion coefficients. present simple methods overcome this problem. use shuffled gradient amplitudes allows accurate NMR measurements, even with time-dependent relaxation rates caused by ions. addition a agent...

&lt;p&gt;A study reported in The Journal of Physical Chemistry Letters (12 (2021) 2370) “boosted mobility” measured by diffusion NMR experiments contains significant errors data analysis and interpretation. We carefully reanalyzed the same find no evidence boosted mobility, we identify several sources error.&lt;/p&gt;

The apparent “boosted mobility” observed by nuclear magnetic resonance (NMR) diffusion measurements is the result of a known artefact. When signal intensities are changing during an NMR measurement for reasons other than diffusion, use monotonically increasing gradient amplitudes produces erroneous coefficient values. We show that no boosted molecular mobility when shuffled applied.

We report on the diffusion mechanism of short, single-stranded DNA molecules with up to 100 nucleobases in agarose gels concentrations 2.0% aim characterize DNA-agarose interaction. The coefficients were measured directly, i.e., without any model assumptions, by pulsed field gradient nuclear magnetic resonance (PFG-NMR). find that coefficient decreases, as expected, an increase both strand length and gel concentration. In addition, we performed Monte Carlo simulations particle a network...

ADVERTISEMENT RETURN TO ISSUEPREVLetter to the EditorNEXTComment on "Molecules, Ultimate Nanomotor: Linking Chemical Reaction Intermediates their Molecular Diffusivity"Jan-Philipp Günther*Jan-Philipp GüntherMax Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569 Stuttgart, Germany*Email: [email protected]More by Jan-Philipp Güntherhttps://orcid.org/0000-0002-8083-0658, Lucy L. FillbrookLucy FillbrookSchool of Chemistry, UNSW Sydney, NSW 2052, AustraliaMore...

A study reported in The Journal of Physical Chemistry Letters (12 (2021) 2370) “boosted mobility” measured by diffusion NMR experiments contains significant errors data analysis and interpretation. We carefully reanalyzed the same find no evidence boosted mobility, we identify several sources error.

The measured changes in self-diffusion of small molecules during reactions have been attributed “boosted mobility”. We demonstrate the critical role changing concentrations paramagnetic ions on nuclear magnetic resonance (NMR) signal intensities, which lead to erroneous measurements diffusion coefficients. present simple methods overcome this problem. use shuffled gradient amplitudes allows accurate NMR measurements, even with time-dependent relaxation rates caused by ions. addition a agent...