A5090838936- Neurobiology and Insect Physiology Research
- Insect and Arachnid Ecology and Behavior
- Insect Utilization and Effects
- Insect-Plant Interactions and Control
- Insect behavior and control techniques
- Insect and Pesticide Research
- Plant and animal studies
- Liver Disease Diagnosis and Treatment
- Trypanosoma species research and implications
- Animal Behavior and Reproduction
- Biochemical Analysis and Sensing Techniques
- Metabolomics and Mass Spectrometry Studies
- Circadian rhythm and melatonin
- Insect Pest Control Strategies
Yale University
2019-2025
Tanta University
2022
Max Planck Institute for Chemical Ecology
2015-2018
Max Planck Society
2013-2015
Evolutionary Genomics (United States)
2015
Intraspecific olfactory signals known as pheromones play important roles in insect mating systems. In the model Drosophila melanogaster, a key part of pheromone-detecting system has remained enigmatic through many years research terms both its behavioral significance and activating ligands. Here we show that Or47b-and Or88a-expressing sensory neurons (OSNs) detect fly-produced odorants methyl laurate (ML), myristate, palmitate. Fruitless (fru(M))-positive Or47b-expressing OSNs ML...
Detecting danger is one of the foremost tasks for a neural system. Larval parasitoids constitute clear to Drosophila, as up 80% fly larvae become parasitized in nature. We show that Drosophila melanogaster and adults avoid sites smelling main parasitoid enemies, Leptopilina wasps. This avoidance mediated via highly specific olfactory sensory neuron (OSN) type. While larval OSN expresses receptor Or49a tuned odor iridomyrmecin, adult both Or85f addition detects wasp odors actinidine...
Tsetse flies transmit trypanosomes-parasites that cause devastating diseases in humans and livestock-across much of sub-Saharan Africa. Chemical communication through volatile pheromones is common among insects; however, it remains unknown if how such chemical occurs tsetse flies. We identified methyl palmitoleate (MPO), oleate, palmitate as compounds are produced by the fly
Despite the comprehensive knowledge on odor coding, our understanding of relationship between sensory input and behavioral output in Drosophila remains weak. Here, we measure responses generated by larval adult flies response to 34 fruit odors find that preference for differs from flies. Next, provide a functional analysis full repertoire peripheral olfactory system using same stimulus spectrum. We 90% 53% receptors tested here, respectively, are involved evaluating these odors. Finally,...
The vinegar fly Drosophila melanogaster is equipped with two peripheral olfactory organs, antenna and maxillary palp. involved in finding food, oviposition sites mates. However, the functional significance of palp remained unknown. Here, we screened sensory neurons (MP-OSNs) using a large number natural odor extracts to identify novel ligands for each MP-OSN type. We found that type sole or primary detector specific compound, detects these compounds high sensitivity. next dissected...
Dipteran or "true" flies occupy nearly every terrestrial habitat, and have evolved to feed upon a wide variety of sources including fruit, pollen, decomposing animal matter, even vertebrate blood. Here we analyze the molecular, genetic cellular basis odor response in tsetse fly Glossina morsitans, which feeds on blood humans their livestock, is vector deadly trypanosomes. The G. morsitans antenna contains specialized subtypes sensilla, some line sensory pit not found fruit Drosophila. We...
Abstract Parasitoid wasps inflict widespread death upon the insect world. Hundreds of thousands parasitoid wasp species kill a vast range species. Insects have evolved defensive responses to threat wasps, some cellular and behavioral. Here we find an unexpected response adult Drosophila presence certain wasps: accelerated mating behavior. Flies exposed begin more quickly. The effect is mediated via changes in behavior female fly depends on visual perception. sight induces dramatic...
Hepatocellular carcinoma (HCC) is the most common cause of cancer-related death.Although there are several therapeutic options, including surgery, chemotherapy, and radiation that helpful in early stages HCC, sorafenib an effective systemic therapy advanced not all HCC cases susceptible to sorafenib.This a significant issue treatment hepatocellular faces globally.Recently, new methods for prevention have been developed using phytochemicals.One phytochemical substance many researchers...
Abstract Parasitoid wasps inflict widespread death upon the insect world. Hundreds of thousands parasitoid wasp species kill a vast range species, and many such are used globally to control pests. Insects have evolved defensive responses threat wasps, some cellular behavioral. However, nature these mechanisms that underlie them await further exploration. Here we find an unexpected response adult Drosophila presence certain wasps: accelerated mating behavior. Flies exposed begin more quickly....