A5030605501- Pain Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Pain Management and Treatment
- Adipose Tissue and Metabolism
- Biochemical effects in animals
- Stress Responses and Cortisol
- Muscle activation and electromyography studies
- Pediatric Pain Management Techniques
- Laser Applications in Dentistry and Medicine
- Neuropeptides and Animal Physiology
- Migraine and Headache Studies
- Adenosine and Purinergic Signaling
- Muscle metabolism and nutrition
- Neuroendocrine regulation and behavior
- Healthcare Regulation
- Exercise and Physiological Responses
- Indigenous Health and Education
- Nitric Oxide and Endothelin Effects
- Anesthesia and Neurotoxicity Research
- Acupuncture Treatment Research Studies
- Healthcare and Venom Research
- Muscle Physiology and Disorders
- Vagus Nerve Stimulation Research
- Science and Education Research
- Animal Genetics and Reproduction
University of Pittsburgh
2024
Universidade Federal do Rio Grande do Sul
2017-2023
Hospital de Clínicas de Porto Alegre
2017-2023
Universidade de Brasília
2010
Behavioral alterations, like mechanical and thermal hyperalgesia, modulation of biomarkers in the peripheral central nervous systems (CNS) are markers chronic pain. Transcranial direct current stimulation (tDCS) with exercise is a promising therapy for pain due to its neuromodulatory capacity.To assess individual effects tDCS, exercise, two combined on nociceptive response BDNF, IL-1β, IL-4 levels CNS structures rats model.For 8 consecutive days after establishment neuropathic by inducing...
The present study aimed at investigating both the early and long-term effects of maternal deprivation as well gender on neuromotor reflexes, anxiety behavior thermal nociceptive responses. A total 64 Wistar rats pups (32 males, 32 females) were utilized deprived their mother for 3 h/daily, from postnatal day 1 (P1) until P10. Successively, animals divided into 2 groups: control group (C) - no subjected to intervention; maternal-deprived (MD): deprivation. reflexes evaluated through righting...
Summary Key mechanisms underlying chronic pain occur within the neural circuitry of dorsal horn. Recent genome-wide association studies (GWAS) have identified genetic variants associated with predisposition to pain. However, most these lie in regulatory non-coding regions that so far not been linked spinal cord function. Here, we take a multi-species approach determine whether impact elements horn neurons. We first built more comprehensive single cell atlas; filling gaps by generating...
This scientific article seeks to analyze the applicability of Non-Prosecution Agreement (ANPP), which is a decriminalizing institute brought in by Anti-Crime Package created Law 13.964, December 24, 2019. In this article, we have chosen address applicable environmental crimes. The problem will be feasibility applying crimes, considering their nature damage environment. general objective understand challenges NPA specific objectives are investigate whether agreement crimes that do not involve...
Abstract Background This study assessed the effects of an acute stress model upon long‐term hyperalgesia induced by repeated morphine administration in neonatal rats. We also evaluated neurotrophins and cytokines levels; expressions adenosine acetylcholine receptors, acetylcholinesterase enzyme at spinal cord. Material methods Male Wistar rats were subjected to or saline from P8 P14. Thermal mechanical hyperesthesia using hot plate (HP) von Frey (vF) tests, respectively, postnatal day P30...
BACKGROUND AND OBJECTIVES:The expression of nerve growth factor (NGF) in the large-size neurons may represent a key role neuronal synaptic plasticity and re-organization function after injury.Transcranial direct current stimulation (tDCS) is non-invasive method cerebral represents promising tool to pain management since it promotes neuroplasticity central system, can be combined with other interventions.The aim was investigate effects tDCS NGF levels peripheral nervous system structures rats...
Our aim was to evaluate if a single session of physical activity until fatigue promotes analgesic effects in fibromyalgia model, and this effect is enhanced by low dose naltrexone. 40 male Wistar rats were used, between 55 65 days-old (≥ 250g). The model developed using the reserpine (1mg/kg, 3 consecutive days). divided into five groups: control (reserpine vehicle+naltrexone vehicle); 2nd group: (reserpine+naltrexone+physical exercise); 3rd (reserpine+naltrexone vehicle +physical 4th...
Several herbal compounds have been used in different cutaneous wounds aiming to decrease the time of cicatrization. The use bark from S. barbatiman tree represents a very common kind treatment animals and human Brazil. In this work, application extract was carried analyze cicatrization process 2cm, which were produced surgically on dorse 20 mice. first group, 15 treated using ointment formulation containing 10% ethanol extracts barbatiman. control 5 do not received treatment. measured each 7...
This study evaluated the effects of association between obesity and chronic stress on temporal pattern serum levels biochemical hormonal markers. Obesity model was achieved by hypercaloric diet exposure. Wistar rats were divided into four groups: standard chow (C), (HD), + (S), (SHD) analysed at three time points: ZT0, ZT12 ZT18. Chronic performed 1 h/per day, 5 days/per week, during 80 days. The presence in naïve animals’ insulin release accomplished. Hypercaloric induced obesity,...