A5013556009- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Nausea and vomiting management
- Anesthesia and Neurotoxicity Research
- Airway Management and Intubation Techniques
- Pain Management and Opioid Use
- Pain Mechanisms and Treatments
- Pediatric Pain Management Techniques
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Intraoperative Neuromonitoring and Anesthetic Effects
- Veterinary Pharmacology and Anesthesia
- Pain Management and Placebo Effect
- Meta-analysis and systematic reviews
- scientometrics and bibliometrics research
- Acupuncture Treatment Research Studies
- Musculoskeletal pain and rehabilitation
- Epilepsy research and treatment
- Optical Imaging and Spectroscopy Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Pituitary Gland Disorders and Treatments
- Neuroscience and Neuropharmacology Research
- Circadian rhythm and melatonin
Aretaeio Hospital
2011-2023
National and Kapodistrian University of Athens
2012-2023
National Hellenic Research Foundation
2020
St Savas Hospital
1994-2015
European Society of Anaesthesiology
2007
Medical College of Wisconsin
2005-2006
Ljubljana University Medical Centre
2006
Evangelismos Hospital
2000
Northwick Park Hospital
1997
Anaesthetic Research Society
1997
We investigated the analgesic efficacy of mexiletine and gabapentin on acute chronic pain associated with cancer breast surgery in 75 patients. They were randomized to receive, a double-blinded manner, 600 mg/d, 1200 or placebo for 10 days. Anesthesia was standardized, all patients had access routine postoperative analgesics demand. The visual analog scale score assessed at rest after movement. Three months later, interviewed identify intensity requirements. Mexiletine reduced codeine...
We evaluated the effect of multimodal analgesia on acute and chronic pain after breast surgery for cancer. Fifty patients scheduled cancer were blindly randomized to receive gabapentin, eutectic mixture local anesthetics cream, ropivacaine in wound or three placebos. Pain (visual analog scale) analgesics recorded postanesthesia care unit (PACU) 3, 6, 9 h 8 days surgery. Three 6 mo later, assessed pain. The treatment group consumed less paracetamol PACU (469 versus 991 mg; P < 0.002) Lonalgal...
We investigated the analgesic efficacy of mexiletine and gabapentin on acute chronic pain associated with cancer breast surgery in 75 patients. They were randomized to receive, a double-blinded manner, 600 mg/d, 1200 or placebo for 10 days. Anesthesia was standardized, all patients had access routine postoperative analgesics demand. The visual analog scale score assessed at rest after movement. Three months later, interviewed identify intensity requirements. Mexiletine reduced codeine...
Guidelines and practice standards for sedation in endoscopy have been developed by various national professional societies. No attempt has made to assess consensus among internationally recognized experts this field.To identify areas of dissent international on a broad range issues pertaining the digestive endoscopy.Thirty-two position statements were reviewed during 1 (1/2)-day meeting. Thirty-two individuals from 12 countries four continents, representing fields gastroenterology,...
<h3>Background and Objectives</h3> A significant percentage of women undergoing breast surgery for cancer may develop neuropathic pain in the chest, and/or ipsilateral axilla upper medial arm, with impairment performing daily occupational activities. We designed this study to determine if perioperative application EMLA (eutectic mixture local anesthetics; AstraZeneca) cream area reduces analgesic requirements, as well acute chronic after surgery. <h3>Methods</h3> Forty-six female patients...
Gabapentin has been suggested to decrease acute postoperative pain. We evaluated the effect of gabapentin on pain after abdominal hysterectomy.Sixty patients scheduled for hysterectomy were randomized receive orally 400 mg 6 hourly or placebo. Treatment started 18 h preoperatively and continued 5 days. Pain (visual analogue score) consumption morphine 48 oral paracetamol/codeine recorded 2, 4, 8, 24 days 3-5 postoperatively. After 1 month, interviewed by phone pain, analgesic intake hospital...
General anesthetics may have nociceptive actions that affect postoperative pain. In studies evaluating pain, the effect of general on analgesic requirements has not been considered except for one recent study suggesting propofol anesthesia provides better analgesia after surgery than isoflurane.In this prospective, blind, randomized trial we recorded (mg morphine) and pain scores (visual analog scale in mm) 2, 4, 8, 24 h postoperatively patients undergoing abdominal hysterectomy or...
The impact factor (IF), a qualitative parameter used to evaluate scientific journals, has several flaws. aim of the study was two its important constraints, journal self-citation and field, investigate potential for improvement.We studied five or six highest journals from each seven medical fields: anesthesiology, dermatology, genetics heredity, immunology, general internal medicine, ophthalmology surgery. To correct self-citation, we divided number 1998 citations papers published in 1996...
Department of Pharmacology and Division Anaesthesia, Medical School, University Athens, Greece
The antiepileptics gabapentin and pregabalin are used as adjuvants to control postoperative pain.The aim of the present study was investigate effect perioperative administration on acute chronic pain analgesic requirements.Department Anaesthesiology, Aretaieio University Hospital, Athens, Greece.Eighty patients scheduled for abdominal hysterectomy or myomectomy were randomly assigned group.The group received 150 mg 8-hourly, starting afternoon before surgery continued until fifth day....
We investigated the effect of pressure application on acupuncture point "extra 1" and a control bispectral index (BIS) values stress in 25 volunteers. In each volunteer, was applied extra 1 for 10 min 5 different days randomized manner. The BIS value recorded before applying point, during every 30 s min, after release. Regarding were instead because acupressure that associated with an unpleasant feeling. Each volunteer asked to score from 0 10. significantly reduced 2.5, 5, 7.5, (P < 0.001...
The doses of propofol that produce loss consciousness were investigated in 26 patients with chronic alcoholism and 20 a history small alcoholic intake undergoing ear, nose, throat surgery under general anesthesia. Last ethanol consumption by the alcoholics was 24 h preoperatively, as they had no access to alcohol when admitted hospital. Propofol infused at rate 1200 mL/h (200 mg/min). required (a) verbal contact (b) ability grasp 20-mL syringe filled water recorded. At this time 2-mL venous...
Sixteen critically ill patients whose tracheas were intubated through the nasal route examined for paranasal sinusitis between 2nd and 3rd day again on 8th after intubation. Between days, 6 of 16 developed either maxillary alone (3 them) or sphenoid (in other 3). By day, all had involving at least one sinus. The most commonly affected sinuses (87%) followed by ethmoid (50%) frontal (12.5%). On 8 intubation, nasotracheal tubes removed replaced orotracheal tubes, tracheostomies performed....
The possible postoperative antiemetic effect of transcutaneous electrical nerve stimulation (TENS) on the P6 point (on Pericardium Channel Hand-Jueyin) was evaluated in 103 women undergoing hysterectomy. TENS applied 30–45 min before induction anesthesia 51 patients and continued for 6 h postoperatively. control group, 52 patients, treated exactly same way but with stimulator turned off. Incidence vomiting assessed blindly 2 h, 4 8 incidence postoperatively significantly less TENS-treated...
Gabapentin and local anaesthetics may decrease postoperative pain analgesic needs. The aim of the study was to investigate effect combination these drugs on needs as well acute late after abdominal hysterectomy.Sixty patients undergoing hysterectomy were randomly assigned receive postoperatively oral gabapentin 400 mg 6 hourly for 7 days plus continuous wound infusion ropivacaine 0.75% 30 h or placebo capsules identical those normal saline h. Morphine consumption (PCA) 48 h, paracetamol 500...
We investigated differences in pain perception between men and women of reproductive age by using Laser-Evoked Potentials (LEPs).Forty-four right-handed healthy volunteers (19 males/25 females), aged 30–40 years were studied. A CO2 laser generated three series 10 thermal pulses (4.5 W) on the radial aspect dorsum left hand. recording montage for late LEPs was used, potentials each stimuli averaged to calculate mean latency amplitude subject. Volunteers scored verbally intensity (Numerical...
<h3>Background and Objectives</h3> Breast surgery for cancer is associated with chronic pain sensory abnormalities. The present study investigates the effect of regional block, oral mexiletine, combination both, on acute breast surgery. <h3>Methods</h3> One hundred patients scheduled received either block 18 mL 1% ropivacaine intraoperatively mexiletine first 6 postoperative days (R + M group), or placebo PL), normal saline instead (PL M), PL). Postoperative analgesic requirements were...
In Brief We studied the effect of sevoflurane and desflurane on regional cerebral oxygenation (rSO2). Twenty-two patients undergoing abdominal hysterectomy received for 15 min each 30 apart under steady-state conditions in a randomized, crossover manner to maintain bispectral index (BIS) 40–50. another 22 same anesthesia surgery BIS was maintained at 20–30. During 15-min administration anesthetic rSO2, BIS, inspired end-tidal concentrations, CO2, Spo2, systolic diastolic blood pressures,...
Acupuncture has anxiolytic effects. We investigated the effect of acupuncture on Bispectral Index (BIS) values and anxiety. Fifty patients were randomly assigned to group A receive for 15 minutes extra 1 point (yintang) or C, where they received same treatment a control located 2 cm lateral end right eyebrow. BIS recorded before acupuncture; during every 30 seconds 90 when was accomplished. Anxiety level assessed after by verbal score scale (VSS) (0=no anxiety, 10=worst anxiety)....