- Medical Imaging and Pathology Studies
- MRI in cancer diagnosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Congenital Anomalies and Fetal Surgery
- Liver Disease Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Soft tissue tumors and treatment
- Heterotopic Ossification and Related Conditions
- Muscle and Compartmental Disorders
- Youth, Drugs, and Violence
- Gallbladder and Bile Duct Disorders
- Prostate Cancer Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Child and Adolescent Psychosocial and Emotional Development
- Lung Cancer Treatments and Mutations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Maternal and Neonatal Healthcare
- Autism Spectrum Disorder Research
- Bone Tumor Diagnosis and Treatments
- Cerebral Venous Sinus Thrombosis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cancer and Skin Lesions
- Vasculitis and related conditions
- Lung Cancer Diagnosis and Treatment
- Genetic and Kidney Cyst Diseases
Hospital de Dona Estefânia
2022-2024
Hospitais da Universidade de Coimbra
1995-2023
Hospital Garcia de Orta
2016-2023
Hospital de Santa Maria
2013-2023
Centro Hospitalar do Porto
2017-2022
Medicina
2022
Centro Hospitalar Póvoa de Varzim Vila do Conde EPE
2020
University of Coimbra
1995-2020
Nanium (Portugal)
2020
Pitié-Salpêtrière Hospital
2017
Introduction: Crohn's Disease (CD) is a chronic inflammatory disorder with heterogeneous presentation. While diarrhea, abdominal pain, and weight loss are hallmarks, atypical manifestations can obscure the diagnosis. This report highlights an unusual presentation of CD to emphasize need for comprehensive diagnostic strategies. Case Report: A 25-year-old male presented peripheral edema, anorexia, distension but lacked classic gastrointestinal (GI) symptoms. Laboratory findings included...
A Síndrome HELLP é uma complicação potencialmente fatal da pré-eclâmpsia, caracterizada por hemólise, elevação das enzimas hepáticas e plaquetopenia. Essa condição surge devido a um conjunto de processos complexos interligados, incluindo desenvolvimento placentário inadequado, disfunção endotelial, estresse oxidativo ativação anormal do sistema imunológico cascata coagulação. Esses fatores levam danos endoteliais difusos, alterações na microcirculação comprometimento função múltiplos órgãos....
A pré-eclâmpsia é uma condição gestacional caracterizada por hipertensão e proteinúria após a 20ª semana de gestação, Sua fisiopatologia envolve interação complexa fatores vasculares, genéticos imunológicos, com placenta desempenhando papel central. doença pode levar complicações graves, como insuficiência renal, acidente vascular cerebral restrição do crescimento fetal. prevalência da varia globalmente, sendo maior em regiões menor acesso cuidados médicos, no Brasil, onde representa das...
To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age‐ and sex‐matched typically developing children. This analytical case–control study compared patients ASDs between the ages 2 6 years who had a language delay not associated any other pathology. Amplitudes ABR waves V; absolute latencies (ALs) I, III, interpeak (IPLs) I–III, III–IV, I–V at 90 dB were ASD normally The...
Schwannoma is a benign tumour that arises from Schwann cells of the peripheral nerve sheath, and common head neck. However, intraoral location very uncommon (only 1% all neck schwannomas). We report rare case lingual schwannoma in 20-year-old male patient who presented with small, slow-growing mass over right lateral border tongue 1 year evolution became recently ulcerated. The underwent MRI examination complete surgical excision. Histopathological immunohistochemical confirmed diagnosis.
A depressão materna merece um lugar especial entre as situações em que a qualidade do investimentomaterno se encontra comprometida, não só pela sua frequência, mas também pelo papel ultimamente lhe tem sido atribuído enquanto factor de risco psicopatológico para o desenvolvimento perturbaçõesemocionais na criança. Neste trabalho são analisadas forma mais detalhada representações mentais mães com sintomatologia depressiva e seu impacto nas interacções mãe-criança, partir estudo realizado...
Abstract Objective: To report a case of successful bone-anchored hearing aid implantation in an adult patient with type III osteogenesis imperfecta, which is commonly regarded as contraindication to this procedure. Case report: A 45-year-old man imperfecta presented mixed loss. There was mild sensorineural component both ears, air–bone gap between 45 and 50 dB HL. He implanted aid. The audiological outcome good, no complications good implant stability (as measured by resonance frequency...
Extramedullary disease is an aggressive presentation at diagnosis and relapse for multiple myeloma (MM) patients. Central nervous system (CNS) a very rare manifestation of the extramedullary disease, accounting less than 1% MM on relapse. Neurological symptoms are unspecific usually attributed to other causes. We present two patients with CNS-MM after autologous stem cell transplant highlighting importance clinical suspicion interdisciplinarity diagnostic workup as well need intensive...
Metabolic myopathies are a diverse group of rare genetic disorders associated with recurrent episodes rhabdomyolysis, induced by triggers such as fever or exercise. In these disorders, the energetic metabolism is compromised resulting in damage muscle cells. The diagnosis can be challenging but essential for correct treatment. Carnitine palmitoytransferase II (CPT-II) deficiency most common long-chain fatty acid oxidation defect, adulthood form requiring additional external triggers. authors...
CONDUCT DISORDERS AND ATTENTION DEFICIT HYPERACTIVITY DISORDER: DIAGNOSIS INTERVENTION IN PRIMARY HEALTH CARE Conduct Disorders and Attention Deficit Hyperactivity Disorder are the most common forms of psychopathology in childhood adolescence.This article briefly addresses aspects its management primary health care, including diagnosis, pidemiology, risk protective factors, clinical evaluation, comorbidities, differential prognosis intervention strategies.
Introduction: Prostatic multiparametric magnetic resonance (mpMRI) allows for guided prostate biopsy (PB).Objective: To evaluate localization agreement between mpMRI lesions and histology obtained by cognitive PB radical prostatectomy (RP) surgical specimen (SS). Methods: Out of 115 consecutive biopsied patients, 37 with positive were studied. Sample was characterized regarding age, prostatic volume, PI-RADS, location lesion on mpMRI, dimension, total number fragments obtain PB, directed to...
rEsUMo objetivo: Avaliar o conhecimento acerca de cuidados bucais dos cuidadores primários das crianças atendidas na clínica Odontopediatria uma faculdade no sul do Brasil e sua relação com a prevalência severidade cárie condição periodontal (gengivite) dessas crianças.Métodos: Um questionário semiestruturado foi aplicado aos
Parents' emotion socialization practices are an important source of influence in the development children's emotional competencies This study examined parental reactions to child negative emotions a clinical sample using cluster analysis approach and explored associations between clusters parents' adjustment. The comprised 80 parents Portuguese children (aged 3-13 years) attending adolescent psychiatry unit. Measures assess emotions, psychopathological symptoms, dysregulation, adjustment...
Comorbidity between obsessive-compulsive disorder and bipolar has been a well-documented phenomenon in the adult population for several decades. However, scant evidence exists regarding this comorbidity juvenile population. The objective of review is to investigate impact on clinical course therapeutic approaches each individually, with particular focus children adolescents. A scientific was conducted careful analysis available electronic databases: MEDLINE, Embase Cochrane Library. In...
Diffuse pulmonary ossification (DPO) is a rarely diagnosed entity that may present with characteristic imaging features. It listed in the differential diagnosis of lung parenchymal calcifications and should be considered by radiologist if appropriate findings are identified. We report case DPO secondary to mitral stenosis patient whose severe cardiac pathology lead death few weeks after chest CT was done. To date, there no specific treatments proved benefit this pathology.
Racemose neurocysticercosis is an uncommon type of that represents a particularly aggressive infection. It characterized by the presence multiple confluent cysts within subarachnoid space and it carries unique diagnostic challenges. Clinical manifestations include headache, cerebrovascular events, life-threatening hydrocephalus. A 56-year-old female presented with sudden onset headache right-sided hemisensory loss. Brain MRI revealed cystic lesions in consistent racemose left thalamus acute...
A 57-year-old woman with Crohn's disease (ulcerative proctitis) treated mesalazine (5-ASA) developed worsening respiratory distress and cough. The lack of response to antibiotics the results bronchoalveolar lavage led diagnosis mesalazine-related hypersensitivity pneumonitis, an infrequent entity. Symptoms improved after discontinuation administration corticosteroid therapy. authors discuss management this rare condition.A pneumonitis should be considered when unexplained symptoms develop...
Nocardiosis is a rare infection in immunocompetent patients. Nocardia spp. an uncommon cause of prostate abscesses and responsible for only 1-2% brain abscess. Hematogenous dissemination can occur, presentation more than two locations required to determine disseminated nocardiosis. The microbiological diagnosis this agent still challenge due the complexity its identification regular laboratories. An early adequate treatment with effective antibiotics are critical treating entity. We report...
<b><i>Introduction:</i></b> Malignant peritoneal mesothelioma (MPM) is a rare malignancy of the mesothelial cells in peritoneum. The best-defined risk factor asbestos exposure, but germline mutations BAP1 also increase susceptibility to this tumor. diagnosis MPM challenging since clinical manifestations are often nonspecific. <b><i>Case Presentation:</i></b> We describe case 53-year-old former construction worker with prior exposure....