A5057183271- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and Medication Impact
- Pregnancy and preeclampsia studies
- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Global Maternal and Child Health
- Tumors and Oncological Cases
- Ectopic Pregnancy Diagnosis and Management
- Prenatal Substance Exposure Effects
- Ethics and Legal Issues in Pediatric Healthcare
- Spinal Dysraphism and Malformations
- Fetal and Pediatric Neurological Disorders
- Genetic Syndromes and Imprinting
- Tracheal and airway disorders
- Teratomas and Epidermoid Cysts
- Cancer Risks and Factors
- Chronic Lymphocytic Leukemia Research
- Patient Dignity and Privacy
- COVID-19 Impact on Reproduction
- Green IT and Sustainability
- Abdominal Trauma and Injuries
- Hepatitis C virus research
- Musculoskeletal Disorders and Rehabilitation
- Organ and Tissue Transplantation Research
University of Cape Town
2011-2024
Groote Schuur Hospital
2010-2022
University of Edinburgh
2010
Polyhydramnios is associated with both maternal and fetal adverse outcomes. Idiopathic polyhydramnios, regardless of its severity category, was considered not to be an increase in In contrast, when conditions such as congenital chromosomal abnormalities or diabetes mellitus are detected, neonatal outcomes can up five times higher. We thus aimed document the patients mild, moderate severe polyhydramnios according whether underlying cause found which management protocol followed. conducted a...
The prenatal screening programme for Down syndrome (DS) in the South African public health sector remains primarily based on advanced maternal age (AMA). We assessed changes over time and effectiveness of this within a Cape Town district.Retrospective analysis Groote Schuur Hospital Cytogenetic Laboratory Pregnancy Counselling Clinic databases audit delivery records at primary care facility.The number amniocenteses performed AMA consecutive 5-year periods reduced progressively from 786 1981...
Abstract Fetal goitrous hypothyroidism is a rare condition in euthyroid pregnant women. Complications such as tracheal and esophageal compression with resultant polyhydramnios, well the possibility of neurodevelopmental effects hypothyroidism, have prompted prenatal treatment intra‐amniotic L‐thyroxine. We report case this its utero management. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound,
Spinal neural tube defects (NTDs) result from failure of closure that normally occurs at 15 - 28 days after conception. Birth prevalence figures for spina bifida vary, but on average are around 0.1%. There no recent South Africa, previous studies have shown an incidence 0.77 6.1/1 000 live births, with higher incidences in rural areas. The true NTDs is thought to be higher, difficult calculate as this includes both spontaneous and therapeutic pregnancy losses.
The Western Cape Pregnancy Exposure Registry (PER) was established at two public sector healthcare sentinel sites in the province, South Africa, to provide ongoing surveillance of drug exposures pregnancy and associations with outcomes.
The Department of Radiology at Groote Schuur Hospital, Cape Town, South Africa, has been performing fetal magnetic resonance imaging (MRI) since 2007. Fetal MRI findings have not previously analysed to correlate them with antenatal and postnatal findings.To determine the most common indication for MRI, ultrasound (US), postmortem findings.This was a retrospective study carried out between January 2006 December 2011. Seventy cases complete medical records were included. Antenatal US compared,...
of their previous investigatioi and follow up.The control group comprised 530 normal children seen in hospital for reasons unrelated to the genitourinary tract (308 girls, 222 boys; age range 5-14, mean 8-8 years; 375 were aged 9 or under).Statistical analysis was with fourfold tables X2 test.Twenty three patients (34%) reflux but only 42 (8%) controls enuretic (x2=42-7, p<0-001) (table ).There no significant difference prevalence primary nocturnal enuresis between different grades bilateral...
Abstract Background Lack of data on the burden and scope congenital disorders (CDs) in South Africa undermines resource allocation limits ability to detect signals from potentially teratogenic pregnancy exposures. Methods We used routine electronic Western Cape Pregnancy Exposure Registry (PER) determine overall individual prevalence CD identified neonatal surface examination at birth Cape, Africa, 2016–2022. was confirmed by record review. The contribution late (≤24 months) antenatal...
There is limited literature on the known risk of HIV transmission during amniocentesis. Before introduction highly active antiretroviral therapy (HAART), amniocentesis was avoided owing to increased transmission. Recent suggests that it safe perform in women HAART with undetectable viral loads. In South Africa (SA), many access antenatal care late pregnancy and there often insufficient time attain loads within a pre-viability period. Guidelines recommendations for invasive testing...
Many studies, largely from high-income countries (HIC), have reported outcomes in babies with trisomy 18 (T18), a paucity of data Africa. Knowledge is important counselling women prenatally diagnosed T18. We aimed to review all cases T18 between January 2006 and December 2021.Demographic data, diagnosis, gestation outcome were obtained the Astraia® database patient files.We included 88 pregnant whom 46 terminated their pregnancies (30 beyond 24 weeks' gestation). Three underwent foeticides,...
The arguments in the paper by Dhai et al. may be summarised as follows: Since childbirth take place vaginal delivery or caesarean section, a choice must made and consent to is necessary for section. affirm patient's right choose, together with observation that safety of limited public sector. Rising section rates differences between private sector are noted. They argue sound ethical legal principles should used determining mode delivery. choose enshrined process informed consent, which...
Ultrasound in pregnancy has become standard of care, resulting an increased number antenatally diagnosed fetal anomalies. It isimportant to have a consistent approach the management these abnormalities. This may include offering termination pregnancy,standard care or non-aggressive/palliative care. A categorisation anomalies and options is proposed assist with thesedecisions, underpinned by ethical framework.
Born in Cape Town on 14 April 1928, Harold passed away peacefully with his wife June next to bed Connecticut, USA, 1 2013. In her loss, is supported by 2 children Micheline and Michael, who live relatively nearby their families.
He travelled to Cape Town for further education, first at Zonnebloem College, then Trafalgar High School.He graduated MB ChB UCT in 1951, the Swaziland-born medical graduate
The theme of this year's SASUOG Congress is 'The Magic Ultrasound'. It truly magical when the face fetus in utero can be seen three dimensions as clearly a photograph taken newborn. Even more dramatic real-time motion video gyrating, sucking its fingers and moving hands away from to reveal smile. When twins playing with each other's umbilical cords, small ventricular septal defects detected at 12 weeks' gestation, pre-eclampsia growth restriction predicted by ultrasound combined blood tests,...
Historically, pregnancy was regarded as a state of confinement. More recently, however, research has demonstrated many potential health benefits aerobic and strength-conditioning exercise in the postpartum period. It is now considered safe, even advisable, for otherwise healthy pregnant women to initiate or continue an active lifestyle during pregnancy. Many anatomical physiological changes take place while there no evidence suggest that associated with any maternal fetal adverse outcomes,...