A5035123688- Maternal and Perinatal Health Interventions
- Glioma Diagnosis and Treatment
- Maternal and fetal healthcare
- Cancer, Hypoxia, and Metabolism
- Brain Metastases and Treatment
- Neuroendocrine regulation and behavior
- Shoulder Injury and Treatment
- Nerve Injury and Rehabilitation
- Reproductive Health and Contraception
- Shoulder and Clavicle Injuries
- Amino Acid Enzymes and Metabolism
- Electrolyte and hormonal disorders
- Neuroblastoma Research and Treatments
- melanin and skin pigmentation
- Muscle and Compartmental Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Bioactive natural compounds
- Breastfeeding Practices and Influences
- Microtubule and mitosis dynamics
- Dye analysis and toxicity
- Cancer Diagnosis and Treatment
- Pregnancy-related medical research
- Pituitary Gland Disorders and Treatments
- Tumors and Oncological Cases
- Enzyme function and inhibition
Medisch Centrum Haaglanden
2017-2018
University of British Columbia
1999
McMaster University Medical Centre
1992
Ferring Pharmaceuticals (Switzerland)
1992
Carbetocin, a long-acting oxytocin analog, was administered by intravenous and intramuscular injection to 40 women 24 48 hours postpartum. Intravenous of 8 30 μg produced tetanic uterine contraction within 2 minutes, lasting about 6 followed rhythmic contractions for further 60 ± 18 minutes. Intramuscular 10 70 also in less than 11 an additional 119 69 The prolonged duration activity after compared with the carbetocin significant (p = 0.020). Carbetocin mild lower abdominal cramping most...
Abstract. A 23 year old woman with diabetes insipidus who had previously been treated pitressin, pituitary snuff and chlorpropamide, was DDAVP during pregnancy. concentrations immunoassayed as vasopressin were determined in maternal serum breast milk. Oxytocin antibodies also serum.
The retention and distribution of tritiated methotrexate (MTX-3H) after direct intracerebral or intraneoplastic injection were studied in mice bearing subcutaneous ependymoblastomas. After MTX-3H nontumor-bearing animals, a large amount the drug was retained head, much more than could have been systemic administration, there rpaid spreading through ipsilateral hemisphere. Intraneoplastic tumors produced rapid tumors. Intially, mainly intersititial fluid followed by earlier cellular uptake...
✓ The authors describe a brain tumor model for chemotherapy studies. is an intracerebral ependymoblastoma that kills the host in short time (median survival, 27.5 days) and yields consistent, uniform survival curves. A suspension of cells injected into right frontal lobe mouse by means stereotaxic frame, produces highly invasive, almost entirely intracranial tumor. use mice permits extensive chemotherapeutic trials tumors at low cost. It felt this will prove to be very useful studies chemotherapy.
✓ An intracranial mouse glioma model was used to study the effectiveness of chemotherapy with methotrexate (MTX) or radiotherapy. Maximum tolerable doses MTX were established by toxicity studies in nontumor-bearing mice for intraperitoneal and intracerebral routes drug administration without leucovorin as an antidote. These maximum then given either route directly into tumor bearing tumors. The proved be extremely useful assessing modalities studied, including repeated intraneoplastic...
Currently available diagnostic tracers for brain tumors are not specific. Tumor-specific would improve the detection of by gamma encephalography. Glucose is an important substrate tumor metabolism and known to be taken up in large amounts. The authors have studied five labeled carbohydrates attempt find a tumor-specific tracer: three were tritiated (L-galactose-1-3H, L-fucose-3H, 4,6-dideoxy-xylo-hexose-3H) two radioiodinated (methyl-6-125I-6-deoxy-D-glucoside 6-125I-6-deoxy-D-glucose)....