A5050575326- Genetic and rare skin diseases.
- Cancer-related molecular mechanisms research
- Inflammasome and immune disorders
- Stroke Rehabilitation and Recovery
- Axon Guidance and Neuronal Signaling
- Autophagy in Disease and Therapy
- Neurological Disease Mechanisms and Treatments
- Dermatologic Treatments and Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Hedgehog Signaling Pathway Studies
- Body Image and Dysmorphia Studies
- Medicinal Plants and Bioactive Compounds
- Dementia and Cognitive Impairment Research
- Transcranial Magnetic Stimulation Studies
- Laser and Thermal Forming Techniques
- EEG and Brain-Computer Interfaces
- Cancer and Skin Lesions
- Herpesvirus Infections and Treatments
- Optical Imaging and Spectroscopy Techniques
- Frailty in Older Adults
- Restless Legs Syndrome Research
- Dysphagia Assessment and Management
- Dermatological and Skeletal Disorders
- Mast cells and histamine
- Pain Mechanisms and Treatments
China Rehabilitation Research Center
2021-2025
Capital Medical University
2016-2025
Advanced Interconnect Technologies (China)
2023
Capital University
2021
Xuan Wu Hospital of the Capital Medical University
2017
Cutaneous features of hyperandrogenism in polycystic ovary syndrome (PCOS) include acne, hirsutism, seborrhea, androgenic alopecia (AGA), and acanthosis nigricans (AN). However, the relationships have not been well known broadly terms clinical biochemical markers.The aim this study was to investigate metabolic parameters relation cutaneous characters women with without PCOS.This a cross-sectional retrospective including 186 PCOS 113 age-matched women. Acne grade, AGA, AN were recorded....
Aging-related cognitive impairment (ARCI) is rapidly becoming a healthcare priority. However, there currently no excellent cure for it. Cognitive-exercise dual-task intervention (CEDI) promising method to improve ARCI, while the underlying mechanisms remain unclear. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) are involved in onset, development, rehabilitation of ARCI. This study aimed investigate effects CEDI role regulation lncRNA NEAT1/miR-124-3p on caveolin-1-PI3K/Akt/GSK3β...
Evidence for the efficacy of cognitive-motor dual-task (CMDT) training in patients with post-stroke cognitive impairment (PSCI) and no dementia is still lacking. More importantly, although some studies on effect CMDT show an improvement performance, results are controversial, intervention mechanism function not clear. The main purpose this study was to analyze effects function, neuron electrophysiology, frontal lobe hemodynamics PSCI.Here we tested PSCI patients. Forty subjects who met...
Parkinson's disease remains one of the leading neurodegenerative diseases in developed countries. Despite well-defined symptomology and pathology, complexity prevents a full understanding its etiological mechanism. Mechanistically, α-synuclein misfolding aggregation appear to be central for progression, but mitochondrial dysfunction, dysfunctional protein clearance ubiquitin/proteasome systems, neuroinflammation have also been associated with disease. Particularly, neuroinflammation, which...
Repetitive transcranial magnetic stimulation (rTMS) has been shown to effectively improve impaired swallowing in Parkinson's disease (PD) patients with dysphagia. However, little is known about how rTMS affects the corresponding brain regions this patient group. In case-control study, we examined data from 38 PD dysphagia who received treatment at Beijing Rehabilitation Medicine Academy, Capital Medical University. The high-frequency of motor cortex once per day for 10 successive days....
Porokeratosis (PK), first described in 1983, is a chronic parakeratotic skin disorder. Clinical types include porokeratosis of Mibelli (PM), disseminated superficial PK, actinic (DSAP), facial and ptychotropica (PP). Dermoscopic images PK show an obvious annular margin with scales atrophied center.[1] Wood's lamp pictures present diamond necklace-like structure.[2] Gene mutations mevalonate pathway enzymes, such as kinase (MVK), phosphomevalonate (PMVK), decarboxylase (MVD), farnesyl...
Chronic cerebral ischemia (CCI) can lead to vascular cognitive impairment, but therapeutic options are limited. Cognitive-exercise dual-task (CEDT), as a potential rehabilitation intervention, attenuate impairment. However, the related mechanisms remain unclear. In this study, 2-vessel occlusion (2-VO) in male SD rats was performed establish CCI model. The were treated with cognitive, exercise, or CEDT intervention for 21 days. Morris water maze (MWM) test used assess ability. TUNEL staining...
The objective was to investigate the risk factors for poor pain control in patients with herpes zoster (HZ)-associated neuropathic treated drugs combined nerve block therapy. Neuropathic commonly follows HZ. Nerve therapy is most used clinical treatment such pain, combining anti-inflammation and analgesia prevent peripheral sensitization of nerve. Using practice data from a cohort study at our research center, we established multivariate logistic regression model potential zoster-associated...
The probe card is a key component to realizing the interconnection between wafer and ATE (Automatic Test Equipment) in process of test. characteristics high-end SOC chip, such as multi-pin, fine pin pitch, high performance, put forward higher requirements on stability performance card, board thickness tolerance, warping graph alignment, interlayer aspect ratio, impedance accuracy, even appearance quality, which are several times than ordinary requirements. At same time, flatness needles also...
OPINION article Front. Aging Neurosci., 18 October 2022Sec. Neurocognitive and Behavior Volume 14 - 2022 | https://doi.org/10.3389/fnagi.2022.1051056
Abstract Parkinson’s disease remains one of the leading neurodegenerative diseases in developed countries. Despite well-defined symptomology and pathology, complexity prevents a full understanding its’ etiological mechanism. Mechanistically, α-synuclein misfolding aggregation appears central for progression, but mitochondrial dysfunction, dysfunctional protein clearance ubiquitin/proteasome systems, neuroinflammation have also been associated with disease. Particularly neuroinflammation,...
Serum triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL-C), high (HDL-C), uric acid (UA) levels and fasting blood glucose (FBG) were measured in 67 patients with chronic spontaneous urticaria(CSU) 66 healthy subjects (controls). Results showed that the rates of increased serum TG FBG CSU higher than those controls (19% vs. 6%, χ2=5.309, P 0.05). The rate rising accompanied by angioedema(4/9)was without angioedema(7%, χ2=7.181, P<0.05). Key words: Urticaria,...
Abstract Background: Aging induces degenerative changes in the body and causes cognitive dysfunction, which has a significant negative impact on daily lives of older adults. At present, there are limited effective interventions to slow incidence Aging-related impairment or even dementia. Among them, exercise training worthy further research, especially research mechanisms. Studies have shown that LncRNA miRNA play an important role occurrence, development, rehabilitation aging-related...
The clinical data of 7 patients with porokeratosis (PK) were analyzed retrospectively. In PK patients, 4 cases disseminated superficial actinic (DSAP), 1 case was (DSP), giant (GP) and hypertrophic (HP). characteristic cutaneous manifestations annular well-circumscribed keratotic plaques slightly atrophic center elevated border. All shared a common histological hallmark, the cornoid lamella. Four DSAP had family medical history, consistent autosomal dominant inheritance. DSP, GP HP denied...