A5076988688- Health disparities and outcomes
- COVID-19 and Mental Health
- Mental Health Treatment and Access
- Mental Health and Patient Involvement
- Aging and Gerontology Research
- Dementia and Cognitive Impairment Research
- Mental Health Research Topics
- Health, psychology, and well-being
- Psychological Well-being and Life Satisfaction
- Face Recognition and Perception
- Intergenerational Family Dynamics and Caregiving
- Mindfulness and Compassion Interventions
- Health Policy Implementation Science
- Functional Brain Connectivity Studies
- Geriatric Care and Nursing Homes
- Musculoskeletal pain and rehabilitation
- Anesthesia and Neurotoxicity Research
- Technology Use by Older Adults
- Media Influence and Health
- Digital Mental Health Interventions
- Stroke Rehabilitation and Recovery
- Advanced MRI Techniques and Applications
- Multisensory perception and integration
- Health and Well-being Studies
- Health, Environment, Cognitive Aging
Hong Kong Polytechnic University
2023-2025
University of Hong Kong
2015-2024
Chinese University of Hong Kong
2019-2023
First Affiliated Hospital of Nanchang University
2016-2023
Nanchang University
2016-2023
Hong Kong Jockey Club
2022
Hubei Polytechnic University
2020-2021
Huazhong University of Science and Technology
2010
Background COVID-19-related information on social media is overabundant and sometimes questionable, resulting in an “infodemic” during the pandemic. While previous studies suggest usage increases risk of developing anxiety symptoms, how induced affects attitudes behaviors less discussed, let alone a global Little known about relationship between older adults using pandemic their anxiety, toward trust information, to avoid contracting COVID-19. Objective The goal this study was investigate...
Loneliness is a significant and independent risk factor for depression in later life. Particularly Asian culture, older people may find it less stigmatising to express loneliness than depression. This study aimed adapt simple screen use Chinese, ascertain its relevance detecting depressive symptoms as community screening tool.This cross-sectional was conducted among 1653 adults aged 60 years or above living the Hong Kong. convenient sample recruited from four local non-governmental...
Emerging evidence has shown that mindfulness-based cognitive therapy (MBCT) is effective in improving depressive symptoms the older population. However, accessibility to MBCT limited by shortage of psychotherapists or mindfulness teachers. One potential solution involve social workers, who have knowledge and skills promote individual community well-being various settings, delivering modified enhance its sustainability. This study examined effectiveness an eight-week age-modified led...
Abstract Personal stigma towards late-life depression, a barrier to help-seeking for older adults, may be reduced by improved depression literacy. This study adopted pre-and-post-test design investigate the relationships between types of literacy and reduction. We recruited 976 adults aged greater than or equal fifty mental wellness education programme. The results paired t-tests showed that programme participants’ personal stigma. Their knowledge about symptoms (t = 9.10, P < .01)...
Objectives: This study investigated the association between healthy lifestyle comprised of multiple domains, gender, and cognitive function in older Chinese people Hong Kong.Methods: We conducted a cross-sectional analysis with data from 1,831 community-dwellers aged 65 years above. Participants' basic demographics, comorbidity, six factors: diet; smoking; alcohol drinking; physical, mental, social activities were surveyed. Cognitive was assessed using Cantonese Montreal Assessment...
Abstract Network analysis provides an innovative approach to examining symptom-to-symptom interactions in mental health, and adverse external conditions may change the network structures. This study compared networks of common risk factors health problems (loneliness, depressive symptoms, anxiety symptoms) community-dwelling older people before during COVID-19. Older adults (aged ≥ 60) at for depression were recruited through non-governmental organizations. Loneliness, symptoms measured...
Expertise in Chinese character recognition is marked by reduced holistic processing (HP), which depends mainly on writing rather than reading experience. Here we show that, while simplified and traditional readers demonstrated a similar level of HP when characters shared between the scripts, were less perceiving characters; this effect depended their performance. However, two groups did not differ characters, regardless difference performances. Our image analysis showed high visual...
Abstract The brain‐derived neurotrophic factor ( BDNF )‐tyrosine kinase B (TrkB) ‐TrkB) signalling pathway plays a crucial role in regulating learning and memory. Synaptophysin provides the structural basis for synaptic plasticity depends on processing subsequent TrkB signalling. Our previous studies demonstrated that maternal exposure to propofol during late stages of pregnancy impaired memory rat offspring. purpose this study is investigate whether ‐TrkB involved propofol‐induced...
Group cognitive stimulation therapy (CST) is a 7-week activity-based non-pharmacological intervention for people with mild to moderate dementia. Despite consistent evidence of clinical efficacy, the and brain mechanisms CST remain unclear. Theoretically, group as person-centred approach may work through promoting social interaction personhood, executive function, language use, especially in higher brain/cognitive reserve. To explore these putative mechanisms, structural MRI resting-state...
Abstract Background Late-life depression is common, modifiable, yet under-treated. Service silos and human resources shortage contribute to insufficient prevention intervention. We describe an implementation research protocol of collaborative stepped care peer support model that integrates community mental health aged services address service fragmentation, using productive ageing recovery principles involve older people as supporters resource issue. Methods/design This a non-randomised...
Objectives: Intact cognition is a key determinant of quality life. Here, we investigated the relative contribution age and physical frailty to global everyday in older adults.Methods: Data came from 1396 community-dwelling, healthy Chinese adults aged 65 or above. We measured their using Cantonese Montreal Cognitive Assessment, with short Lawton Instrumental Activities Daily Living scale, Fatigue, Resistance, Ambulation, Illness, Loss Weight Scale grip strength. Multiple regression analysis...
Microglia are the major immune cells in central nervous system. Microglial activation can be beneficial or detrimental depending on stimuli and physiopathological environment. is involved a variety of neurodegenerative disorders. Different anesthetic agents have exhibited diverse effects microglial engulfment process. The anthocyanin callistephin has been demonstrated to antioxidant anti‑inflammatory properties, these were assessed present study, with focus its effect activation. Mouse C8‑4B...
Abstract Aims Late-life depression has substantial impacts on individuals, families and society. Knowledge gaps remain in estimating the economic associated with late-life by symptom severity, which implications for resource prioritisation research design (such as modelling). This study examined incremental health social care expenditure of depressive symptoms severity. Methods We analysed data collected from 2707 older adults aged 60 years over Hong Kong. The Patient Health Questionnaire-9...
Abstract Background Propofol is an intravenous anesthetic agent that commonly induces significant neuroapoptosis. MicroRNAs (miRNAs) have been reported to participate in the regulation of propofol exposure-mediated neurotoxicity. MiR-215, as one miRNAs, was found regulate nerve cell survival. However, mechanism through which miRNAs neurotoxicity still unclear. Methods Real-time PCR used detect miR-215 expression level. Cell viability measured using MTT assay. apoptosis examined via flow...
Internalized ageism and stigma of mental illness may disempower older people impede help-seeking among those at risk depression. Arts are deemed enjoyable, stigma-free, conducive to health, a participatory approach can engage empower potential service users. This study aimed co-design cultural art program test its feasibility in empowering Chinese Hong Kong preventing depression.Adopting guided by the Knowledge-to-Action framework, we co-designed 9-session group using calligraphy as channel...
Abstract Background and Objectives This study explores the impact of timebanking, where individuals earn time credits, nonmonetary currency, on promoting volunteerism among older adults. Research Design Methods employed a quasi-experimental design with 116 timebank group (TBG) participants 114 comparison (CG) from 2021 to 2022. TBG received credits exchange for rewards, while CG no (i.e., volunteering as usual). The intervention timebanking lasted 1 year. Volunteering behaviors were tracked...
The left-side bias (LSB) effect observed in face and expert Chinese character perception is suggested to be an expertise marker for visual object recognition. However, this limited characters printed a familiar font (font-sensitive LSB effect). Here we investigated whether the font-sensitive effects depend on participants’ familiarity with global structure or local component information of stimuli through examining their transfer across simplified traditional scripts: two scripts share...
Based on the analysis of self-similarity network traffic, a anomaly detection technology is proposed by combining with fuzzy logic so as to explore fractal characteristics traffic. The concepts traffic and security are introduced. Then, model based theory wavelet analysis. Finally, distributed denial service (DDoS) that attacks monitoring intensity judgment method put forward theory. results show autocorrelation function multifractal constructed local Hurst exponent (LHE) can reach mean...
Older adults were perceived as a vulnerable group during the COVID-19 pandemic due to health and mental challenges they faced. The was accompanied by an "infodemic" of overabundant questionable information that has affected older adults' health. As infodemic ageist narratives prevalent online, more anxiety symptoms have been induced among who used social media. Age-friendly communication, advocated World Health Organization's City (AFC) guide, could be antidote providing tailored via...